Primary information |
---|
ID | antitb_1547 |
Peptide Name | Lassomycin |
Sequence | GLRRLFADQLVGRRN |
N-terminal Modification | Free |
C-terminal Modification | Methylation |
Chemical Modification | Free NH- group of first Glycine form NHCO bond with CO group of eight Asparagine to form cyclic bond |
Linear/ Cyclic | Cyclic |
Length | 15 |
Chirality | D |
Nature | Cationic |
Source | Natural |
Origin | Derived from lentzea kentuckyensis |
Species | Mycobacterium tuberculosis |
Strain | Mycobacterium tuberculosis MDR |
Inhibition Concentartion | IC50= 0.8-3 mg/ml |
In vitro/In vivo | in vitro |
Cell Line | NA |
Inhibition Concentartion | NA |
Cytotoxicity | NA |
In vivo Model | NA |
Lethal Dose | NA |
Immune Response | NA |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | NA |
Other Activities | NA |
Pubmed ID | 25613372 |
Year of Publication | 2015 |
3-D Structure | NA |