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FWGALAKGALKLIPSLFSSFSKKD details |
Primary information | |
---|---|
ID | antitb_1185, |
Name | 25019413 |
N-Terminal modification | Pin2 |
C-Terminal Modification | FWGALAKGALKLIPSLFSSFSKKD |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | None |
Chirality | Linear |
Nature | 24 |
Source | L |
Origin | Cationic |
Species | Natural |
Strain | Venom of the African scorpion Pandinus imperator |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis H37Rv |
Cell Line | MIC = 57.7 ± 22.3 μg/ml or 22.1 ± 8.6 μM |
Inhibition Concentration | In vitro |
Sequence | 2014 |
Cytotoxicity | RBC |
In vivo Model | NA |
Lethal Dose | Hemolysis ( IC-50 = 3.3 [1.9–5.7]) |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | Cell wall disruption |
Other activities | Cell wall |
PMID | None |
Year of Publication | Anti-bacterial (E. coli, S. aureus) |
Tertiary Structure (Technique) | Not Predicted), |
Primary information | |
---|---|
ID | antitb_1186, |
Name | 25019413 |
N-Terminal modification | Pin2 |
C-Terminal Modification | FWGALAKGALKLIPSLFSSFSKKD |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | None |
Chirality | Linear |
Nature | 24 |
Source | L |
Origin | Cationic |
Species | Natural |
Strain | Venom of the African scorpion Pandinus imperator |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis muti-drug resistant strain (MDR) clinical isolate |
Cell Line | MIC = 86.5 μg/ml or 33.1 μM |
Inhibition Concentration | In vitro |
Sequence | 2014 |
Cytotoxicity | RBC |
In vivo Model | NA |
Lethal Dose | Hemolysis ( IC-50 = 3.3 [1.9–5.7]) |
Immune Responce | None |
Mechanism of Action | NA |
Target | NA |
Combination Therapy | Cell wall disruption |
Other activities | Cell wall |
PMID | None |
Year of Publication | Anti-bacterial (E. coli, S. aureus) |
Tertiary Structure (Technique) | Not Predicted), |