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Detailed description page of AntiTbPdb

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antitb_1185 details
Primary information
IDantitb_1185
Peptide NamePin2
SequenceFWGALAKGALKLIPSLFSSFSKKD
N-terminal ModificationFree
C-terminal ModificationFree
Chemical ModificationNone
Linear/ CyclicLinear
Length24
ChiralityL
NatureCationic
SourceNatural
OriginVenom of the African scorpion Pandinus imperator
SpeciesMycobacterium tuberculosis
StrainMycobacterium tuberculosis H37Rv
Inhibition ConcentartionMIC = 57.7 ± 22.3 μg/ml or 22.1 ± 8.6 μM
In vitro/In vivoIn vitro
Cell LineRBC
Inhibition ConcentartionNA
CytotoxicityHemolysis ( IC-50 = 3.3 [1.9–5.7])
In vivo ModelNone
Lethal DoseNA
Immune ResponseNA
Mechanism of ActionCell wall disruption
TargetCell wall
Combination TherapyNone
Other ActivitiesAnti-bacterial (E. coli, S. aureus)
Pubmed ID25019413
Year of Publication2014
3-D Structure View in Jmol or Download Structure