AHTpin

Antihypertensive Peptide Inhibitors

• Dipeptide
  • AHT Activity
• Tripeptide
  • AHT Activity
• Tetrapeptide
  • Design peptide
  • Batch submission
  • Protein scan
• Pentapeptide
  • Design peptide
  • Batch submission
  • Protein scan
• Hexapeptide
  • Design peptide
  • Batch submission
  • Protein scan
• 7-12 residues
  • Design peptide
  • Batch submission
  • Protein scan
• 13 residues and above
  • Design peptide
  • Batch submission
  • Protein scan
• AllinOne
  • Variable Length I/P
• Propensity Matrices
  • P. Matrices

User(s) can submit protein sequence (in single letter code) to generate all possible peptide fragments of length 13 or above residues (with predicted antihypertensive ability and physicochemical properties). Mutants of the generated peptide fragments may be generated to design best putative antihypertensive peptide. Graphical display of results is an interesting feature to estimate putative antihypertensive peptides present in whole protein.

(A) Paste Protein sequence (Please paste amino acid sequence in single letter code):

(B) Peptide fragment length: 13 14 15 16 17 18 19 20 25 30

(C) Select model: AMINO ACID COMPOSITION   ATOMIC COMPOSITION

(D) SVM threshold:    -1.0 -0.9 -0.8 -0.7 -0.6 -0.5 -0.4 -0.3 -0.2 -0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 -1.0 -0.9 -0.8 -0.7 -0.6 -0.5 -0.4 -0.3 -0.2 -0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0

(E) Physicochemical property: