Epitopes Across the strains that shows affinity towards more than one HLA-class in VLCvirus

The following table provides information on identifed promiscous epitopes against all nine major oncogenic lung cancer causing virus species. The count of all the predicted promiscous epitopes is given in the table i.e. MHC binder, T cell epitope, B cell epitope or adjuvant. These promiscous epitope have the capability to bind different class of MHC molecules as well as having strong vaccine inducing potential. This will make them as an attratctive vaccine candidate, as they can cover large human popopulation. We have identified promiscous epitopes against all the virus reference proteome used in VLCvirus study. Moreover, we have categorize the promiscous epitopes in different category as provided in the table. The advantage of this categorization can be seen in terms that - if user wants to identify promiscous epitopes that shows affinity with multiple HLA- class as well as should possess B-cell, T-cell and Vaccine adjuvant potential. Then by going through the table, all the user query can be obtained in just a single click.

id Virus_Name Protein_details Gene Protein Virus_Freq MHCI_type HLA_Freq_MHCI MHCII_type HLA_Freq_MHCII Seq
tbvmhc12_22 Human papillomavirus 179, Human papillomavirus KC5, Human papillomavirus 135, Human papillomavirus 157 Q1HVB3|LMP1_EBVA8 Latent membrane protein 1 LMP1 3 4 HLA-B62:, HLA-B*4403:, HLA-B*5401:, HLA-B*3501:, HLA-B*2702:, HLA-B*5301:, HLA-Cw*0702:, HLA-B*51: 8 DRB1_1120, DRB1_1323, DRB1_1302, DRB1_1114 4 WNLHGQALY
tbvmhc12_1 Measles virus (strain Ichinose-B95a), Measles virus (strain Edmonston-Zagreb vaccine), Measles virus (strain Edmonston-AIK-C vaccine) A0A059UAS5|A0A059UAS5_HPV72 Major capsid protein L1 L1 3 3 HLA-B*5401:, HLA-B*51: 2 DRB1_0426, DRB1_1323, DRB1_1114, DRB1_0401 4 FARHFFNRQ
tbvmhc12_3 Measles virus (strain Ichinose-B95a), Measles virus (strain Edmonston-Zagreb vaccine), Measles virus (strain Edmonston-AIK-C vaccine) Q69138|EBNA3_EBVA8 Epstein-Barr nuclear antigen 3 EBNA3 3 3 HLA-A20 Cattle: 1 DRB5_0101, DRB5_0105 2 IKRTRERWR
tbvmhc12_9 Human papillomavirus 202, Human papillomavirus 140, Human papillomavirus 169 E7BQ77|E7BQ77_9PAPI Minor capsid protein L2 L2 3 3 HLA-B*0702:, HLA-B*5201:, HLA-B*3501:, HLA-B8:, HLA-B*51:, HLA-B62: 6 DRB1_1304, DRB1_1321, DRB1_0806, DRB1_0309, DRB1_1128, DRB1_1327, DRB1_1101, DRB1_1328, DRB1_1501, DRB1_1311, DRB1_0301, DRB1_1107, DRB1_1106, DRB1_1307, DRB1_1120, DRB1_1102, DRB1_0305, DRB1_1104, DRB1_1322, DRB1_1506, DRB1_0102, DRB1_1302, DRB1_1121, DRB1_0804, DRB1_1305, DRB1_1301 26 IVKLRRPIF
tbvmhc12_18 Human papillomavirus type 91, Human papillomavirus type 90, Human papillomavirus type 71 U6BRB0|U6BRB0_9PAPI Replication protein E1 E1 3 3 HLA-B14:, MHC-Db:, HLA-B*5301:, HLA-B*2702:, HLA-B*51:, HLA-B*2705: 6 DRB1_1506, DRB1_1307, DRB1_1114, DRB1_1107, DRB1_1302, DRB1_0306, DRB1_0806, DRB1_0307, DRB1_0813, DRB1_1328, DRB1_0308, DRB1_0305, DRB1_1121, DRB1_0301, DRB1_1304, DRB1_0804, DRB1_1301, DRB1_1501, DRB1_0309, DRB1_1128, DRB1_1311, DRB1_0802, DRB1_1322, DRB1_1305, DRB1_1102, DRB1_0817, DRB1_0311, DRB1_1502, DRB1_1327, DRB1_1323, DRB1_1120, DRB1_1106, DRB1_1104, DRB1_0801 34 VRLYFRQEM
tbvmhc12_24 Human papillomavirus type 21, Human papillomavirus type 5, Human papillomavirus type 115 K4MYX6|K4MYX6_9PAPI Regulatory protein E2 E2 3 3 HLA-Cw*0301:, HLA-B14:, HLA-B*2702:, HLA-B*2705:, HLA-B*5401:, HLA-B*5301:, HLA-B*51:, MHC-Kb:, HLA-A2: 9 DRB1_0804, DRB1_1114, DRB1_0801, DRB1_0802, DRB1_0402, DRB1_1323, DRB1_0817, DRB1_0813 8 WRYRKFQNA
tbvmhc12_2 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) P06918|VL2_HPV05 Minor capsid protein L2 L2 3 2 HLA-B*51:, MHC-Db:, MHC-Ld:, HLA-B*5401:, HLA-B14:, HLA-B*5301:, HLA-B*5102:, HLA-B*5103:, HLA-B*5801:, MHC-Db revised:, HLA-B61:, HLA-A2.1: 12 DRB1_1302, DRB1_1120 2 FSLTNRRLV
tbvmhc12_4 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) E7BQ96|E7BQ96_9PAPI Regulatory protein E2 E2 3 2 HLA-B*2702:, HLA-A*3101:, HLA-A3:, HLA-B*2705:, HLA-A*1101: 5 DRB1_1323, DRB1_1102, DRB1_1322, DRB1_0402, DRB1_1121, DRB1_1114 6 IQYWSAVRK
tbvmhc12_5 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) A0A166FKA1|A0A166FKA1_9PAPI Regulatory protein E2 E2 3 2 HLA-B14:, HLA-B*2702:, HLA-B*2705: 3 DRB1_0813, DRB1_0402, DRB1_0804, DRB1_1328, DRB1_1114, DRB1_1121, DRB1_0802, DRB1_1301, DRB1_1302, DRB1_1322, DRB1_0801, DRB1_1323, DRB1_0806, DRB1_1102, DRB1_0817, DRB1_1327, DRB1_1120, DRB1_1304 18 IRFRRGRQQ
tbvmhc12_6 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) A0A059UAS1|A0A059UAS1_HPV72 Replication protein E1 E1 3 2 HLA-A20 Cattle:, HLA-B*2702:, HLA-B*2705: 3 DRB1_0402 1 IRRGHDRAR
tbvmhc12_7 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) D2E909|D2E909_9PAPI Regulatory protein E2 E2 3 2 HLA-B*2702:, HLA-B*51:, HLA-B*2705: 3 DRB1_0701, DRB1_0101, DRB1_1501, DRB1_0102, DRB5_0105, DRB1_0703, DRB1_1506, DRB5_0101 8 IRRVGYQHV
tbvmhc12_8 Human papillomavirus type 7, Human papillomavirus type 73 C0MHS1|C0MHS1_9PAPI Replication protein E1 E1 3 2 HLA-B*2702:, HLA-B*51:, HLA-B14:, HLA-B*3901:, HLA-B*2705:, HLA-B*5401:, HLA-B*5201: 7 DRB1_1305, DRB1_1311, DRB5_0105, DRB1_1501, DRB1_1301, DRB1_1506, DRB1_1322, DRB1_0101, DRB1_1121, DRB1_1101, DRB1_1106, DRB1_1128, DRB1_1307, DRB1_1327, DRB1_0102, DRB1_1328, DRB1_1104, DRB5_0101, DRB1_1102 19 IRYLQGKVV
tbvmhc12_10 Human papillomavirus type 156, Human papillomavirus 165 P25939|TRM1_EBVB9 Tripartite terminase subunit 1 TRM1 3 2 HLA-B*3501:, HLA-B*5201:, HLA-B*5301:, HLA-B62:, HLA-B*51:, HLA-A3:, HLA-B*2702:, HLA-B*2705: 8 DRB1_0402 1 LMKRINSVF
tbvmhc12_11 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) R9QCI1|R9QCI1_9PAPI Protein E6 E6 3 2 HLA-B*51:, HLA-B*2705:, HLA-B*2702:, HLA-Cw*0702: 4 DRB1_1301, DRB1_1121, DRB1_0101, DRB1_1102, DRB1_0701, DRB1_1120, DRB5_0101, DRB1_1328, DRB5_0105, DRB1_0402, DRB1_0703, DRB1_1322, DRB1_1302, DRB1_1327, DRB1_1304, DRB1_0102 16 LRCIFCRRY
tbvmhc12_12 Human papillomavirus type 163, Human papillomavirus type 194 R9QDL4|R9QDL4_9PAPI E4 Not Available 4 2 HLA-B*2702:, HLA-B*2705:, HLA-A20 Cattle: 3 DRB1_1305, DRB1_1121, DRB1_1302, DRB1_1327, DRB1_1301, DRB1_1120, DRB1_1328, DRB5_0105, DRB1_1322, DRB1_1307, DRB1_1102, DRB1_1323, DRB1_1114, DRB1_1304, DRB1_1128, DRB5_0101 16 LRDLKKRLR
tbvmhc12_13 Human papillomavirus type 103, Human papillomavirus type 108 Q8JN95|Q8JN95_9PAPI Major capsid protein L1 L1 3 2 HLA-A20 Cattle:, HLA-B*2702:, HLA-B*2705: 3 DRB5_0105, DRB5_0101 2 LRREQMFIR
tbvmhc12_14 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) A8R8N1|A8R8N1_9PAPI Replication protein E1 E1 3 2 HLA-B*51:, HLA-A20 Cattle:, HLA-B*3902:, HLA-B*5301:, HLA-Cw*0301:, HLA-B14:, HLA-A2: 7 DRB1_0806, DRB1_1327, DRB1_1501, DRB1_1301, DRB1_0817, DRB1_1114, DRB1_0703, DRB1_1121, DRB1_1304, DRB1_1120, DRB1_0802, DRB1_1322, DRB1_0813, DRB1_1506, DRB1_1502, DRB1_0801, DRB1_1302, DRB1_1328, DRB1_0804, DRB1_0701, DRB1_1323, DRB1_1102 22 VKMYRRYEL
tbvmhc12_15 Human papillomavirus type 90, Human papillomavirus type 71 V5W3Y1|V5W3Y1_9PAPI Minor capsid protein L2 L2 3 2 HLA-A20 Cattle:, HLA-A68.1:, HLA-A*3101:, HLA-B*5301:, HLA-A*3302:, HLA-B*51: 6 DRB1_0402 1 VPSRPTISR
tbvmhc12_16 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) M5EE42|M5EE42_9PAPI Replication protein E1 E1 3 2 HLA-B*2705:, HLA-B*2702:, HLA-A1:, HLA-A20 Cattle: 4 DRB1_0309, DRB1_1104, DRB1_1101, DRB1_0404, DRB1_1128, DRB1_1106, DRB1_0301, DRB1_0421, DRB1_0410, DRB1_0408, DRB1_1305, DRB1_0401, DRB1_0402, DRB1_0423, DRB1_1311, DRB1_0426 16 VRECITMVR
tbvmhc12_17 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) K7QR99|K7QR99_9PAPI Protein E6 E6 3 2 HLA-B*2705:, HLA-B*2702: 2 DRB1_0305, DRB1_1501, DRB1_1323, DRB1_1304, DRB1_1302, DRB1_1328, DRB1_0301, DRB1_1121, DRB1_1301, DRB1_1107, DRB1_0308, DRB1_1327, DRB1_0306, DRB1_1120, DRB1_1506, DRB1_1502, DRB1_1102, DRB1_1114, DRB1_1322, DRB1_0813, DRB1_0311, DRB1_0402, DRB1_0307 23 VRGHWRNCC
tbvmhc12_19 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) Q705C7|Q705C7_HPV94 Minor capsid protein L2 L2 3 2 HLA-A3:, HLA-A*1101:, HLA-A68.1:, HLA-A1:, HLA-A*3101: 5 DRB1_1107, DRB1_1106, DRB1_1311, DRB1_1104 4 VVDVSVPVK
tbvmhc12_20 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) Q8JN99|Q8JN99_9PAPI Replication protein E1 E1 3 2 HLA-B*5103:, HLA-B*5401:, MHC-Dd:, HLA-B*5102:, HLA-B*5201:, HLA-B*3701:, HLA-A*0205:, HLA-A*0201:, HLA-A2.1:, HLA-B*5301:, HLA-B61:, HLA-B*51:, HLA-B*5101: 13 DRB1_1307, DRB1_0408, DRB1_1501, DRB1_1101, DRB1_1104, DRB1_1506, DRB1_0802, DRB1_0305, DRB1_1311, DRB1_0701, DRB1_0309, DRB1_1128, DRB1_1502, DRB1_1305, DRB1_0101, DRB1_0703, DRB1_1321, DRB1_0817, DRB1_1106, DRB1_0813 20 WGMVVLMLV
tbvmhc12_21 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) P50775|VE6_HPV22 Protein E6 E6 3 2 HLA-B*5401:, HLA-A20 Cattle: 2 DRB1_1101, DRB1_0801, DRB1_1120, DRB1_1302, DRB1_1114, DRB1_1323, DRB1_0802, DRB1_0804, DRB1_0813, DRB1_0817 10 WKGRCRHCK
tbvmhc12_23 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) P50800|VL2_HPV29 Minor capsid protein L2 L2 3 2 HLA-B*5101:, MHC-Ld:, HLA-B40:, HLA-B*51:, HLA-B*0702:, HLA-B*3501:, HLA-B*5401:, HLA-B*5103:, HLA-B61:, HLA-B*5102:, HLA-B*5301: 11 DRB1_0802, DRB1_0408, DRB1_1101, DRB1_0801, DRB1_1307 5 WPFVPVAPA
tbvmhc12_25 Epstein-Barr virus (strain B95-8), Epstein-Barr virus (strain AG876) U6BNC2|U6BNC2_9PAPI Minor capsid protein L2 L2 3 2 HLA-B*51:, HLA-B*5401:, HLA-B*2705:, HLA-B*2702: 4 DRB1_1323, DRB5_0105, DRB1_0804, DRB1_0813, DRB1_1120, DRB5_0101, DRB1_1114, DRB1_1302, DRB1_0802, DRB1_0801 10 YRRYIQQVK