Peptide Analogs

This module allow users to predict immunomodulatory activity of their peptide. In addition, this module generates all possible analogs of a given peptide (all possible single mutations) and predicts immunomodulatory activity of each mutant along with all the important physicochemical properties (like hydrophobicity, charge, pI). As a possible application, user can identify and alter a particular residue, which can reduce/increase the immunomodulatory potency of a peptide drastically. In summary this module help to design vaccine ajuvants using analog-based approach.

Peptide Submission Form

Paste/Type Peptide Sequence:

Select model for prediction:     Please select prediction method, SVM-based or SVM+motif-based, if you need motif information for prediction.

  •  Dipeptide Composition  
  • Dipeptide Composition + Motif  

    Choose SVM threshold:

        SVM threshold is required for prediction. Moving the threshold value
    in either direction (+1 or -1) will lead to increase
    in probability of correct prediction in that direction.

  • Optional (Peptide Property)

    This server allow users to compute physicochemical property of residues. Please select property you wish to calculate

  •   Hydrophobicity
  •   Steric hinderance
  •   Solvation
  •    Amphiphilicity
  •   Net Hydrogen
  •    Charge
  •    pI
  •    Molecular weight
  • All