Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID1408 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=1; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=1.2; where, 0=No corneal pathology; 1=Comeal infiltrate without significant melti | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1409 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=2.2, where, 0=No corneal pathology; 1=Comeal infiltrate without significant melting; 2=Grade I melting (none to one-third of the corneal surface); 3=Grade II melting (one-third to two-thirds of the corneal surface) and/or mild bulging; 4=Grade III melting (tw | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1410 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=1/Control=1.2; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=3.1, where, 0=No corneal pathology; 1=Comeal infiltrate without signi | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1411 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=4, where, 0=No corneal pathology; 1=Comeal infiltrate without significant melting; 2=Grade I melting (none to one-third of the corneal surface); 3=Grade II melting (one-third to two-thirds of the corneal surface) and/or mild bulging; 4=Grade III melting (two- | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1412 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=1.1/Control=2.7; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=4, where, 0=No corneal pathology; 1=Comeal infiltrate without signi | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1413 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=4, where, 0=No corneal pathology; 1=Comeal infiltrate without significant melting; 2=Grade I melting (none to one-third of the corneal surface); 3=Grade II melting (one-third to two-thirds of the corneal surface) and/or mild bulging; 4=Grade III melting (two- | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1414 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=1.2/Control=4.8; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=4, where, 0=No corneal pathology; 1=Comeal infiltrate without signi | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1415 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=4.2, where, 0=No corneal pathology; 1=Comeal infiltrate without significant melting; 2=Grade I melting (none to one-third of the corneal surface); 3=Grade II melting (one-third to two-thirds of the corneal surface) and/or mild bulging; 4=Grade III melting (tw | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1416 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=2.2/Control=5.3; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1/Control=4.9, where, 0=No corneal pathology; 1=Comeal infiltrate without sig | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1417 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=2.7/Control=5.3; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=1.3/Control=4.9, where, 0=No corneal pathology; 1=Comeal infiltrate without s | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1418 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=2/Control=4.9, where, 0=No corneal pathology; 1=Comeal infiltrate without significant melting; 2=Grade I melting (none to one-third of the corneal surface); 3=Grade II melting (one-third to two-thirds of the corneal surface) and/or mild bulging; 4=Grade III melting (tw | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1419 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=2.8/Control=4.9, where, 0=No corneal pathology; 1=Comeal infiltrate without significant melting; 2=Grade I melting (none to one-third of the corneal surface); 3=Grade II melting (one-third to two-thirds of the corneal surface) and/or mild bulging; 4=Grade III melting ( | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1420 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=4.1/Control=5.6; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=3/Control=4.9, where, 0=No corneal pathology; 1=Comeal infiltrate without sig | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1421 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=4.7/Control=5.6; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=3.5/Control=5, where, 0=No corneal pathology; 1=Comeal infiltrate without sig | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1422 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=4.9/Control=5.8; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=4/Control=5, where, 0=No corneal pathology; 1=Comeal infiltrate without signi | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1423 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=4.8/Control=5.8; Average clinical score according to hours-post inoculation for topically applied bacterial inoculum(treatment till 24 hours post inoculation): Inhibitor=4/Control=5, where, 0=No corneal pathology; 1=Comeal infiltrate without signi | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |
| ID1424 | SequenceFA | NameThiol based metalloproteinase inhibitor | Nature of peptide or cargoPotent inhibitor of corneal coliagenase, alkali-induced corneal ulceration and P. aeruginosa elastase | AssayPeptidase activity checked via enzyme assay, Clinical evaluation and scoring, Statistical analysis | Tissue permeabilityAverage clinical score according to hours-post inoculation for topically and subconjunctivally applied bacterial inoculum(treatment till 26 hours post inoculation): Inhibitor=5.2/Control=5.8, where, 0=No corneal pathology; 1=Comeal infiltrate without significant melting; 2=Grade I melting (none to one-third of the corneal surface); 3=Grade II melting (one-third to two-thirds of the corneal surface) and/or mild bulging; | Tissue SampleOne eye of the New Zealand White rabbits weighing between 2 and 2.5 kg was used as test and the other as control | PUBMED ID2127341 |