A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1025 | Th1004 | Denileukin diftitox | MGADDVVDSSKSFVMENFSS Full view | 255 | IIb | Cancer | Ontak | Seragen Inc | Sterile, white, preservative-free, lyophilized powder. | Intravenous(IV) administration | Antineoplastic Agents | Interleukin-2 receptor subunit alpha,Interleukin-2 receptor subunit beta,Cytokine receptor common subunit gamma |
1406 | Th1066 | Ibritumomab | Heavy Chain: QAYLQQS Full view | 652 | IIb | Cancer | Zevalin | Spectrum Pharmaceuticals | Clear, colorless, sterile, pyrogen-free, preservative-free solution that may contain translucent particles. | Intravenous infusion | N.A. | Digoxin |
1412 | Th1068 | Tositumomab | Heavy Chain 1: QAYLQ Full view | 1351 | IIb | Cancer | Bexxar | Galaxo Smith Kline | Sterile, pyrogen-free, clear to opalescent, colorless to slightly yellow, preservative-free solution | Intravenous(IV) administration | N.A. | Bacterial outer membrane,Lipoteichoic acid synthesis |
1470 | Th1092 | Arcitumomab | Heavy chain 1EVKLVES Full view | 1310 | IIb | Cancer | CEA-Scan | N.A. | N.A. | N.A. | Diagnostic Agents | Vascular endothelial growth factor A,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c, Carcinoembryonic antigen-related cell adhesion molecule 1 |
1583 | Th1125 | Golimumab | N.A. Full view | 0 | IIb | Immunological | Simponi Injection | N.A. | Clear to slightly opalescent, colorless to light yellow solution | Subcutaneous injection | Antipsoriatic Agents and Monoclonal antibodies and TNF inhibitor | Tumor necrosis factor |
1584 | Th1125 | Golimumab | N.A. Full view | 0 | IIb | Immunological | Simponi Injection | N.A. | Sterile concentrated solution of the golimumab antibody | Intravenous infusion | Antipsoriatic Agents and Monoclonal antibodies and TNF inhibitor | Tumor necrosis factor |
1604 | Th1130 | Brentuximab Vedotin | Heavy chain:QIQLQQSG Full view | 664 | IIb | Cancer | Adcetris | Seattle Genetics | Sterile, white to off-white, preservative-free lyophilized cake or powder in single-use vials. | Intravenous infusion | N.A. | Tumor necrosis factor receptor superfamily member 8 |
1628 | Th1139 | Certolizumab Pegol | Light chain: DIQMTQS Full view | 443 | IIb | Immunologcal | Cimzia | UCB | Sterile, white, lyophilized powder for solution or as a sterile, solution in a single-use prefilled 1 mL glass syringe | Subcutaneous injection | TNF inhibitor | Tumor necrosis factor |
1636 | Th1142 | Obinutuzumab | N.A. Full view | 0 | IIb | Cancer | Gazyva | Genentech | Sterile, clear, colorless to slightly brown, preservative free liquid concentrate | Intravenous infusion | Antineoplastic Agents | B-lymphocyte antigen CD20 |
1671 | Th1159 | Gemtuzumab ozogamicin | Light Chain 1: QIVLT Full view | 459 | IIb | Cancer | Mylotarg | Wyeth pharmaceuticals inc | Sterile, white, preservative-free lyophilized powder | Intravenous infusion | Antineoplastic agents and Immunotoxins | Myeloid cell surface antigen CD33, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c |