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SAL_17104 details
Primary information
SALIDSAL_17104
Biomarker nameAscorbic acid [HMDB0000044]
Biomarker TypeNA
Sampling MethodAdult (>18 years old); Gender-female
Collection MethodNA
Analysis MethodNA
Collection SiteSaliva
Disease CategoryCancer
Disease/ConditionOral Cancer
Disease SubtypeNA
Fold Change/ Concentration0.443 +/- 0.085 uM
Up/DownregulatedNA
ExosomalNA
OrganismHomo sapiens
PMID17623524
Year of Publication2007
Biomarker ID54670067
Biomarker CategoryMetabolite
SequenceC([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O
Title of studySalivary vitamins E and C in oral cancer
Abstract of studyLipid peroxidation may be involved in cancer and essential nutrients that can scavenge free radicals, such as vitamins E and C, operate in concert. Levels of antioxidant vitamins E and C were estimated in 50 patients with oral cancer and 24 healthy persons served as control. Significantly lower levels of vitamins E and C were observed in oral cancer patients as compared to controls (P < 0.011). Antioxidant nutrients may be utilized to a greater extent in oral cancer patients to counteract free radical-mediated cell disturbances, resulting in a reduction in salivary antioxidant levels.