| Primary information |
|---|
| SALID | SAL_17100 |
| Biomarker name | alpha-Tocopherol [HMDB0001893] |
| Biomarker Type | NA |
| Sampling Method | Adult (>18 years old); Gender-female |
| Collection Method | NA |
| Analysis Method | NA |
| Collection Site | Saliva |
| Disease Category | Cancer |
| Disease/Condition | Oral Cancer |
| Disease Subtype | NA |
| Fold Change/ Concentration | 0.0062 +/- 0.0041 uM |
| Up/Downregulated | NA |
| Exosomal | NA |
| Organism | Homo sapiens |
| PMID | 17623524 |
| Year of Publication | 2007 |
| Biomarker ID | 14985 |
| Biomarker Category | Metabolite |
| Sequence | CC1=C(C2=C(CC[C@@](O2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=C1O)C)C |
| Title of study | Salivary vitamins E and C in oral cancer |
| Abstract of study | Lipid peroxidation may be involved in cancer and essential nutrients that can scavenge free radicals, such as vitamins E and C, operate in concert. Levels of antioxidant vitamins E and C were estimated in 50 patients with oral cancer and 24 healthy persons served as control. Significantly lower levels of vitamins E and C were observed in oral cancer patients as compared to controls (P < 0.011). Antioxidant nutrients may be utilized to a greater extent in oral cancer patients to counteract free radical-mediated cell disturbances, resulting in a reduction in salivary antioxidant levels. |