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SAL_16963 details
Primary information
SALIDSAL_16963
Biomarker nameCobalt [HMDB0000608]
Biomarker TypeNA
Sampling MethodAdult (>18 years old); Gender-male
Collection MethodNA
Analysis MethodNA
Collection SiteSaliva
Disease CategoryHealthy
Disease/ConditionHealthy
Disease SubtypeNA
Fold Change/ Concentration0.339 +/- 0.509 uM
Up/DownregulatedNA
ExosomalNA
OrganismHomo sapiens
PMID10378074
Year of Publication1999
Biomarker ID104730
Biomarker CategoryMetabolite
Sequence[Co]
Title of studyTrace elements and electrolytes in human resting mixed saliva after exercise
Abstract of studyOBJECTIVES: Exercise is known to cause changes in the concentration of salivary components such as amylase, Na, and Cl. The aim of this investigation was to evaluate the effect of physical exercise on the levels of trace elements and electrolytes in whole (mixed) saliva.METHODS: Forty subjects performed a maximal exercise test on a cycle ergometer. Samples of saliva were obtained before and immediately after the exercise test. Sample concentrations of Fe, Mg, Sc, Cr, Mn, Co, Cu, Zn, Se, Sr, Ag, Sb, Cs, and Hg were determined by inductively coupled plasma mass spectrometry and concentrations of Ca and Na by atomic absorption spectrometry.RESULTS: After exercise, Mg and Na levels showed a significant increase (p < 0.05) while Mn levels fell (p < 0.05). Zn/Cu molar ratios were unaffected by exercise.CONCLUSIONS: Intense physical exercise induced changes in the concentrations of only three (Na, Mg, and Mn) of the 16 elements analysed in the saliva samples. Further research is needed to assess the clinical implications of these findings.