| Primary information |
|---|
| SALID | SAL_16953 |
| Biomarker name | Dimethylamine [HMDB0000087] |
| Biomarker Type | NA |
| Sampling Method | Adult (>18 years old); Gender-male |
| Collection Method | NA |
| Analysis Method | NA |
| Collection Site | Saliva |
| Disease Category | Healthy |
| Disease/Condition | Healthy |
| Disease Subtype | NA |
| Fold Change/ Concentration | 10959 uM |
| Up/Downregulated | NA |
| Exosomal | NA |
| Organism | Homo sapiens |
| PMID | 6802384 |
| Year of Publication | 1982 |
| Biomarker ID | 674 |
| Biomarker Category | Metabolite |
| Sequence | CNC |
| Title of study | Nicotine concentrations in urine and saliva of smokers and non-smokers |
| Abstract of study | Nicotine concentrations were measured in saliva and urine samples collected from 82 smokers and 56 non-smokers after a morning at work. Each subject answered a series of questions related to their recent intentional or passive exposure to tobacco smoke. All non-smokers had measurable amounts of nicotine in both saliva and urine. Those non-smokers who reported recent exposure to tobacco smoke had significantly higher nicotine concentrations (p less than 0.001) than those who had not been exposed; their concentrations overlapped those of smokers who had smoked up to three cigarettes before sampling had the greatest influence on nicotine concentrations (r=0.62 for saliva and r=0.51 for urine). Neither the nicotine for yield of cigarettes nor the self-reported degree of inhalation had any significant effect on nicotine concentrations. |