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SAL_16915 details
Primary information
SALIDSAL_16915
Biomarker nameOleic acid [HMDB0000207]
Biomarker TypeNA
Sampling MethodAdult (>18 years old); Gender-male
Collection MethodNA
Analysis MethodNA
Collection SiteSaliva
Disease CategoryHealthy
Disease/ConditionHealthy
Disease SubtypeNA
Fold Change/ ConcentrationNA
Up/DownregulatedNA
ExosomalNA
OrganismHomo sapiens
PMID1268322
Year of Publication1976
Biomarker ID445639
Biomarker CategoryMetabolite
SequenceCCCCCCCC/C=C\CCCCCCCC(=O)O
Title of studyGas chromatographic mass spectrometric evaluation of free organic acids in human saliva
Abstract of studyExcellent resolution and subsequent identification of free organic acids extracted from mixed, unstimulated human saliva was obtained by gas chromatography using high resolution open tubular glass capillary columns coupled with mass spectrometry computer instrumentation. In addition to the organic acids, identified as their trimethylsilyl derivaties, the presence of 2,6-di-t-butylcresol--a food preservative--and cholesterol was established by mass spectrometry. The effects of aspirin ingestion as well as diurnal variation were studied to demonstrate the possible clinical significance of this noninvasive approach to metabolic profiling.