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SAL_16334 details
Primary information
SALIDSAL_16334
Biomarker nameTrigonelline
Biomarker TypeNA
Sampling MethodAbout 65 Yusho patients and 32 controls in locations where Yusho occurred : Tamanoura Town, Naru Town, and Nagasaki City in Nagasaki
Collection MethodSaliva samples were collected from 3 Yusho patients
Analysis MethodCE-TOFMS
Collection SiteWhole Saliva
Disease CategoryPoisoning
Disease/ConditionYusho Disease
Disease SubtypeNA
Fold Change/ Concentration<1
Up/DownregulatedDecrease
ExosomalNA
OrganismHomo sapiens
PMID26226676
Year of Publication2015
Biomarker ID5570
Biomarker CategoryMetabolite
SequenceC[N+]1=CC=CC(=C1)C(=O)[O-]
Title of studyMetabolomics of Salivary Biomarkers in Yusho Patients
Abstract of studyYusho patients had many symptoms, and mouth dryness was one of the important oral symptoms. Presently, some Yusho patients complain of mouth dryness. In the present study, we measured mouth dryness by using an oral moisture checking device and examined metabolites of saliva by using metabolome analysis. We found no difference between Yusho patients and controls in terms of mouth dryness. Concerning metabolomes of saliva, there were some metabolites in Yusho patients that were not in controls.