| Primary information |
|---|
| SALID | SAL_11287 |
| Biomarker name | Glycated hemoglobin A |
| Biomarker Type | NA |
| Sampling Method | This case control study has been done on 44 diabetic (type II) and 44 healthy subjects. |
| Collection Method | For collection of unstimulated saliva, from the subjects were asked to spit the saliva into 50 ml laboratory tubes |
| Analysis Method | Spectrophotometry |
| Collection Site | Saliva |
| Disease Category | Metabolic Disorder |
| Disease/Condition | Type II diabetes |
| Disease Subtype | NA |
| Fold Change/ Concentration | NA |
| Up/Downregulated | Upregulated |
| Exosomal | NA |
| Organism | Homo sapiens |
| PMID | 31235125 |
| Year of Publication | 2019 |
| Biomarker ID | P69905 |
| Biomarker Category | Protein |
| Sequence | MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR |
| Title of study | The effect of glycemic control on salivary lipid peroxidation in type II diabetic patients |
| Abstract of study | BACKGROUND AND OBJECTIVE: Hyperglycemia and some disturbance in antioxidant system lead to free radicals production and oxidative stress. Assessment of some products of oxidative stress could be effective in evaluation of diabetic control. This study aimed at evaluation of glycemic control on salivary lipid peroxidation in diabetic patients. METHODS: This case control study has been done on 44 diabetic (type II) and 44 healthy subjects. Un-stimulated saliva was collected and correlation between malondialdehid (MDA) as an end -product of lipid peroxidation and HbA1c was assessed. RESULTS: MDA and HbA1c of diabetic patients were significantly higher than control group. There was a indirect correlation between MDA and glycemic control level. CONCLUSION: Evaluation of salivary MDA levels could be useful in prediction of glycemic control. |