Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_2231Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Chickencytoplasm of basal cells of the epithelium in the isthmus, uterus and vaginaLeucine-rich Repeat (LRR) DomainQ7ZTG5.fastaQ7ZTG5843NANA293306752017Pubchem_assay
PRRID_2231Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Chickencytoplasm of basal cells of the epithelium in the isthmus, uterus and vaginaLeucine-rich Repeat (LRR) DomainQ7ZTG5.fastaQ7ZTG5843NANA293306752017Pubchem_assay
PRRID_2232Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanchorioamniotic membranesLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA293306752017Pubchem_assay
PRRID_2232Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanchorioamniotic membranesLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA293306752017Pubchem_assay
PRRID_2233Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904NANA293306752017Pubchem_assay
PRRID_2233Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904NANA293306752017Pubchem_assay
PRRID_2234Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 8 (TLR8)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainQ9NR97.fastaQ9NR971041NANA293306752017Pubchem_assay
PRRID_2234Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 8 (TLR8)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainQ9NR97.fastaQ9NR971041NANA293306752017Pubchem_assay
PRRID_2235Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Horsecell surface and in the cytoplasm of bronchiolar epithelial cellsLeucine-rich Repeat (LRR) DomainQ2EEY0.fastaQ2EEY01031NANA293306752017Pubchem_assay
PRRID_2235Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Horsecell surface and in the cytoplasm of bronchiolar epithelial cellsLeucine-rich Repeat (LRR) DomainQ2EEY0.fastaQ2EEY01031NANA293306752017Pubchem_assay
PRRID_2236Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceNALeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835NANA292647452017Pubchem_assay
PRRID_2236Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceNALeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835NANA292647452017Pubchem_assay
PRRID_2237Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humancell surfaceLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA292639322017Pubchem_assay
PRRID_2237Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humancell surfaceLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA292639322017Pubchem_assay
PRRID_2238Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanPlateletsleucine-rich-repeat (LRR) , nucleotide-binding domain (NBD), caspase activation and recruitment domain (CARD)O00206.fastaO00206839release soluble factors to modulate the immune responseNA292205942017Pubchem_assay
PRRID_2238Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanPlateletsleucine-rich-repeat (LRR) , nucleotide-binding domain (NBD), caspase activation and recruitment domain (CARD)O00206.fastaO00206839release soluble factors to modulate the immune responseNA292205942017Pubchem_assay
PRRID_2239Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalCauses Mastitis, an infection of the mammary glandToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanmammary tissueLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291138062017Pubchem_assay
PRRID_2239Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalCauses Mastitis, an infection of the mammary glandToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanmammary tissueLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291138062017Pubchem_assay
PRRID_2240Lipopolysaccharide (LPS)

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E. coli K12(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalanti- inflammatory activityToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanU937 cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291137972017Pubchem_assay
PRRID_2240Lipopolysaccharide (LPS)

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E. coli K12(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalanti- inflammatory activityToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanU937 cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291137972017Pubchem_assay
PRRID_2241Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalUrinary Tract infectionToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbladder and uroepithelial cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA290663052017Pubchem_assay
PRRID_2241Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalUrinary Tract infectionToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbladder and uroepithelial cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA290663052017Pubchem_assay
PRRID_2242Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNANAO00206.fastaO00206839NANA290662552017Pubchem_assay
PRRID_2242Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNANAO00206.fastaO00206839NANA290662552017Pubchem_assay
PRRID_2243Lipopolysaccharide (LPS)

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Gram negative bacteria(Leptospira spp.)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalinfectionToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceNALeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NAELISA290389562017Pubchem_assay
PRRID_2243Lipopolysaccharide (LPS)

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Gram negative bacteria(Leptospira spp.)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalinfectionToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceNALeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NAELISA290389562017Pubchem_assay
PRRID_2244Lipopolysaccharide (LPS)

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B. subtilis and E. coli(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAOfbGRP3Gastrin-releasing peptide receptor (GRP)O. furnacalis larvaeNAtwo N-linked glycosylation sites, two O-linked glycosylation sites, the putative cell adhesive site (QGD), a potential kinase C phosphorylation site (SAR) and a glycosyl hydrolase family 16 domain.NANANANANA290322412017NA
PRRID_2244Lipopolysaccharide (LPS)

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B. subtilis and E. coli(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAOfbGRP3Gastrin-releasing peptide receptor (GRP)O. furnacalis larvaeNAtwo N-linked glycosylation sites, two O-linked glycosylation sites, the putative cell adhesive site (QGD), a potential kinase C phosphorylation site (SAR) and a glycosyl hydrolase family 16 domain.NANANANANA290322412017NA
PRRID_2245Lipopolysaccharide (LPS)

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Gram-negative bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalFormation of a complex between PI 3-kinase and MyD88, induction of IL-1β, TNF-α and macrophage inflammatory protein (MIP)-2, induce proinflammatory cytokine production through NF-KB signaling , Functional maturation of mouse macrophages, induction of TNF-α by Human Monocyte Cultures, Production of major proinflammatory cytokines such as IL-1, IL-6, or TNF-α; activate DC and promote the development of Th-like responsesToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMouse macrophagesLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835NANA290283692017Pubchem_assay
PRRID_2245Lipopolysaccharide (LPS)

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Gram-negative bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalFormation of a complex between PI 3-kinase and MyD88, induction of IL-1β, TNF-α and macrophage inflammatory protein (MIP)-2, induce proinflammatory cytokine production through NF-KB signaling , Functional maturation of mouse macrophages, induction of TNF-α by Human Monocyte Cultures, Production of major proinflammatory cytokines such as IL-1, IL-6, or TNF-α; activate DC and promote the development of Th-like responsesToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMouse macrophagesLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835NANA290283692017Pubchem_assay
PRRID_2246Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorrPtCTL-2C type Lectin (CTL/CLR)Portunus trituberculatusNACarbohydrate recognition DomainNANANArecognize nonself invaders and also work as an opsonin to eliminate invadersPAMPs binding assay289163582017NA
PRRID_2246Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorrPtCTL-2C type Lectin (CTL/CLR)Portunus trituberculatusNACarbohydrate recognition DomainNANANArecognize nonself invaders and also work as an opsonin to eliminate invadersPAMPs binding assay289163582017NA
PRRID_2247Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorPmToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Pinctada fucata martensiiHemocytesLeucine-rich Repeat (LRR) DomainNANANAplay a vital role in the induction of innate immunity and is therefore associated with allograft immunity in the pearl oyster P. fucata martensii.NA288936452017NA
PRRID_2247Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorPmToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Pinctada fucata martensiiHemocytesLeucine-rich Repeat (LRR) DomainNANANAplay a vital role in the induction of innate immunity and is therefore associated with allograft immunity in the pearl oyster P. fucata martensii.NA288936452017NA
PRRID_2248Lipopolysaccharide (LPS)

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Gram-negative bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorCgLRRIG-1Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2248Lipopolysaccharide (LPS)

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Gram-negative bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorCgLRRIG-1Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2249Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorCgLRRIG-2Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2249Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorCgLRRIG-2Pattern recognition receptor (PRR)oyster Crassostrea gigasMuscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas.Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domainNANANAimmune effectors or pro-inflammatory factors as well as PRRs in oyster.PAMPs binding assay288890112017NA
PRRID_2250Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorSSc5DScavenger receptor (SR)NANASRCR-Containing N-Terminal DomainNANANAtissue homeostasis, host defence reactivity and regulation of immune reactions and inflammation,NA288787732017NA
PRRID_2250Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorSSc5DScavenger receptor (SR)NANASRCR-Containing N-Terminal DomainNANANAtissue homeostasis, host defence reactivity and regulation of immune reactions and inflammation,NA288787732017NA
PRRID_2251Lipopolysaccharide (LPS)

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V. harveyi (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorrFmLC4Pattern recognition receptor (PRR)aquatic shrimpHepatopancreasCRD and Ca+ bindingNANANAcontribute a role in the shrimp immune defense through its specific binding and agglutination.ELISA288449662017NA
PRRID_2251Lipopolysaccharide (LPS)

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V. harveyi (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalinnate immunity elicitorrFmLC4Pattern recognition receptor (PRR)aquatic shrimpHepatopancreasCRD and Ca+ bindingNANANAcontribute a role in the shrimp immune defense through its specific binding and agglutination.ELISA288449662017NA
PRRID_2252Lipopolysaccharide (LPS)

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S. aureus (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalIncreases expression of Bmintegrin β3 .Bmintegrin β3IntegrinsBombyx moriHemocytesNANANANABmintegrin β3 knockdown promoted PPO1, PPO2, BAEE, SPH78, SPH125, and SPH127 expression and accelerated the melanization process.qRT-PCR288269892017NA
PRRID_2252Lipopolysaccharide (LPS)

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S. aureus (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalIncreases expression of Bmintegrin β3 .Bmintegrin β3IntegrinsBombyx moriHemocytesNANANANABmintegrin β3 knockdown promoted PPO1, PPO2, BAEE, SPH78, SPH125, and SPH127 expression and accelerated the melanization process.qRT-PCR288269892017NA
PRRID_2253Lipopolysaccharide (LPS)

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Pseudomonas aeruginosa (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalstimulation of THP-1 macrophagesMUC1 mucinPattern recognition receptor (PRR)Humansurface of epithelial cells and some hematopoietic cellsNAA0A087X2A4.fastaA0A087X2A4484phagocytic activity and cytokine productionELISA288227662017Pubchem_assay
PRRID_2253Lipopolysaccharide (LPS)

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Pseudomonas aeruginosa (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalstimulation of THP-1 macrophagesMUC1 mucinPattern recognition receptor (PRR)Humansurface of epithelial cells and some hematopoietic cellsNAA0A087X2A4.fastaA0A087X2A4484phagocytic activity and cytokine productionELISA288227662017Pubchem_assay
PRRID_2254Lipopolysaccharide (LPS)

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Pseudomonas aeruginosa (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalstimulation of THP-1 macrophagesMUC1 mucinPattern recognition receptor (PRR)Micesurface of epithelial cells and some hematopoietic cellsNAQ02496.fastaQ02496630phagocytic activity and cytokine productionELISA288227662017Pubchem_assay
PRRID_2254Lipopolysaccharide (LPS)

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Pseudomonas aeruginosa (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalstimulation of THP-1 macrophagesMUC1 mucinPattern recognition receptor (PRR)Micesurface of epithelial cells and some hematopoietic cellsNAQ02496.fastaQ02496630phagocytic activity and cytokine productionELISA288227662017Pubchem_assay
PRRID_2255Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in agingNA288015212017Pubchem_assay
PRRID_2255Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in agingNA288015212017Pubchem_assay
PRRID_2256Lipopolysaccharide (LPS)

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Gram-negative bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in plaque- associated brain tissue of AD model miceNA288015212017Pubchem_assay
PRRID_2256Lipopolysaccharide (LPS)

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Gram-negative bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceBrainLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835mRNA ‚Üë in plaque- associated brain tissue of AD model miceNA288015212017Pubchem_assay
PRRID_2257Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbrain(hippocampus, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2257Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbrain(hippocampus, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2258Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMicrogliaLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835involved in both amyloid-β uptake and inflammatory cytokine productionNA288015212017Pubchem_assay
PRRID_2258Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)MiceMicrogliaLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835involved in both amyloid-β uptake and inflammatory cytokine productionNA288015212017Pubchem_assay
PRRID_2259Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Micemicroglia (mouse striatum)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835TLR4 knockout: neuroprotective in ischemiaNA288015212017Pubchem_assay
PRRID_2259Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Micemicroglia (mouse striatum)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835TLR4 knockout: neuroprotective in ischemiaNA288015212017Pubchem_assay
PRRID_2260Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceneurons (mouse cortex)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835protein ‚Üë, proapoptotic in ischemiaNA288015212017Pubchem_assay
PRRID_2260Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceneurons (mouse cortex)Leucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835protein ‚Üë, proapoptotic in ischemiaNA288015212017Pubchem_assay
PRRID_2261Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Ratrat brain (vasculature)Leucine-rich Repeat (LRR) DomainQ9QX05.fastaQ9QX05835protein ‚Üë, activation in ischemic strokeNA288015212017Pubchem_assay
PRRID_2261Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Ratrat brain (vasculature)Leucine-rich Repeat (LRR) DomainQ9QX05.fastaQ9QX05835protein ‚Üë, activation in ischemic strokeNA288015212017Pubchem_assay
PRRID_2262Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceprimary mouse astrocytesLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835activation in response to α-synucleinNA288015212017Pubchem_assay
PRRID_2262Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Miceprimary mouse astrocytesLeucine-rich Repeat (LRR) DomainQ9QUK6.fastaQ9QUK6835activation in response to α-synucleinNA288015212017Pubchem_assay
PRRID_2263Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBind to Ficolins and stimulate innate immunity.MnFico1Pattern recognition receptor (PRR)Macrobrachium nipponenseGillssignal peptide and a fibrinogen-related domain.NANANAregulate the expression of AMP genes.qRT-PCR287649852017NA
PRRID_2263Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBind to Ficolins and stimulate innate immunity.MnFico1Pattern recognition receptor (PRR)Macrobrachium nipponenseGillssignal peptide and a fibrinogen-related domain.NANANAregulate the expression of AMP genes.qRT-PCR287649852017NA
PRRID_2264Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBind to Ficolins and stimulate innate immunity.MnFico2Pattern recognition receptor (PRR)Macrobrachium nipponenseGillssignal peptide and a fibrinogen-related domain.NANANAregulate the expression of AMP genes.qRT-PCR287649852017NA
PRRID_2264Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBind to Ficolins and stimulate innate immunity.MnFico2Pattern recognition receptor (PRR)Macrobrachium nipponenseGillssignal peptide and a fibrinogen-related domain.NANANAregulate the expression of AMP genes.qRT-PCR287649852017NA
PRRID_2265Lipopolysaccharide (LPS)

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P. gulae (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalCauses inflammation and activation of TLR2.Toll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceMacrophagesLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784activate NF-κB.NA286300662017Pubchem_assay
PRRID_2265Lipopolysaccharide (LPS)

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P. gulae (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalCauses inflammation and activation of TLR2.Toll-like receptor 2 (TLR2)Toll-like receptor (TLR)MiceMacrophagesLeucine-rich Repeat (LRR) DomainQ9QUN7.fastaQ9QUN7784activate NF-κB.NA286300662017Pubchem_assay
PRRID_2266Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalActivation of CLRs.rCaNTCC type Lectin (CTL/CLR)Carassius auratusLiverCarbohydrate recognition domain (CRD)NANANApathogen recognition in Qihe 538 crucian carpMicrobial binding assay286026832017NA
PRRID_2266Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalActivation of CLRs.rCaNTCC type Lectin (CTL/CLR)Carassius auratusLiverCarbohydrate recognition domain (CRD)NANANApathogen recognition in Qihe 538 crucian carpMicrobial binding assay286026832017NA
PRRID_2267Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalActivation of MjSRC.MjSRCScavenger receptor (SR)Marsupenaeus japonicusHemocytesCCP and MAM domains of MjSRCA0A1L2DC21.fastaA0A1L2DC21692phagocytosis of pathogenic microbes by macrophage and dendritic cellPolysacharides binding assay286026822017Pubchem_assay
PRRID_2267Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalActivation of MjSRC.MjSRCScavenger receptor (SR)Marsupenaeus japonicusHemocytesCCP and MAM domains of MjSRCA0A1L2DC21.fastaA0A1L2DC21692phagocytosis of pathogenic microbes by macrophage and dendritic cellPolysacharides binding assay286026822017Pubchem_assay
PRRID_2268Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantCqTollToll-like receptor (TLR)Cherax quadricarinatusHemocytesextracellular domain of 19 leucine-rich repeats residues, a transmembrane domain and an intracellular domain of 138 amino acids.NANANACqToll involved in anti-WSSV responseqRT-PCR284793462017NA
PRRID_2268Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantCqTollToll-like receptor (TLR)Cherax quadricarinatusHemocytesextracellular domain of 19 leucine-rich repeats residues, a transmembrane domain and an intracellular domain of 138 amino acids.NANANACqToll involved in anti-WSSV responseqRT-PCR284793462017NA
PRRID_2269Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantBjLRPLow density lipoprotein receptor-related protein (LRP)B. japonicumgill, muscle, notochord and testisLY-EGF-CRD- EGF-CRDNANANAphagocytosis of apoptotic cellsqRT-PCR284002712017NA
PRRID_2269Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantBjLRPLow density lipoprotein receptor-related protein (LRP)B. japonicumgill, muscle, notochord and testisLY-EGF-CRD- EGF-CRDNANANAphagocytosis of apoptotic cellsqRT-PCR284002712017NA
PRRID_2270Lipopolysaccharide (LPS)

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Vibrio (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantLeulectinPattern recognition receptor (PRR)Marsupenaeus japonicusHemocytesCTLDNANANAHemocytic PhagocytosisPull- down and far-Western assays282581972017NA
PRRID_2270Lipopolysaccharide (LPS)

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Vibrio (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantLeulectinPattern recognition receptor (PRR)Marsupenaeus japonicusHemocytesCTLDNANANAHemocytic PhagocytosisPull- down and far-Western assays282581972017NA
PRRID_2271Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantrBjAVIDIN1Pattern recognition receptor (PRR)B. japonicumHemocytesNANANANAphagocytosis of bacteria by macrophages,qRT-PCR280694302017NA
PRRID_2271Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantrBjAVIDIN1Pattern recognition receptor (PRR)B. japonicumHemocytesNANANANAphagocytosis of bacteria by macrophages,qRT-PCR280694302017NA
PRRID_2272Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantrBjAVIDIN1Pattern recognition receptor (PRR)B. japonicumHemocytesNANANANAphagocytosis of bacteria by macrophages,qRT-PCR280694302017NA
PRRID_2272Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantrBjAVIDIN1Pattern recognition receptor (PRR)B. japonicumHemocytesNANANANAphagocytosis of bacteria by macrophages,qRT-PCR280694302017NA
PRRID_2273Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAAcTREM1Pattern recognition receptor (PRR)NAcell-surface receptorNANANANANANA283441692017NA
PRRID_2273Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAAcTREM1Pattern recognition receptor (PRR)NAcell-surface receptorNANANANANANA283441692017NA
PRRID_2274Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAAcTREM2Pattern recognition receptor (PRR)NAcell-surface receptorNANANANANANA283441692017NA
PRRID_2274Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAAcTREM2Pattern recognition receptor (PRR)NAcell-surface receptorNANANANANANA283441692017NA
PRRID_2275Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2275Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)NANALeucine-rich Repeat (LRR) DomainNANANANANA280630152017NA
PRRID_2276Lipopolysaccharide (LPS)

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Vibrio harveyi (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalPathogenic infectionFmLC5C type Lectin (CTL/CLR)Fenneropenaeus merguiensishemocytestwo similar carbohydrate recognition domains (CRDs), each CRD contains a Ca2+ binding site-2 and a QPD motif specific for galactose-bindingNANANANAqRT-PCR289585862017NA
PRRID_2276Lipopolysaccharide (LPS)

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Vibrio harveyi (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalPathogenic infectionFmLC5C type Lectin (CTL/CLR)Fenneropenaeus merguiensishemocytestwo similar carbohydrate recognition domains (CRDs), each CRD contains a Ca2+ binding site-2 and a QPD motif specific for galactose-bindingNANANANAqRT-PCR289585862017NA
PRRID_2277Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA282889102017NA
PRRID_2277Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA282889102017NA
PRRID_2279Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responserMrLecC type Lectin (CTL/CLR)NANANANANANANANA278183422017NA
PRRID_2279Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responserMrLecC type Lectin (CTL/CLR)NANANANANANANANA278183422017NA
PRRID_2281Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responseMrCTLC type Lectin (CTL/CLR)NANANANANANANANA276208192017NA
PRRID_2281Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responseMrCTLC type Lectin (CTL/CLR)NANANANANANANANA276208192017NA
PRRID_2283Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAPcFBN1Pattern recognition receptor (PRR)NANANANANANANANA274172292017NA
PRRID_2283Lipopolysaccharide (LPS)

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Gram-negative and Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAPcFBN1Pattern recognition receptor (PRR)NANANANANANANANA274172292017NA