Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_2231 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Chicken | cytoplasm of basal cells of the epithelium in the isthmus, uterus and vagina | Leucine-rich Repeat (LRR) Domain | Q7ZTG5.fasta | Q7ZTG5 | 843 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2231 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Chicken | cytoplasm of basal cells of the epithelium in the isthmus, uterus and vagina | Leucine-rich Repeat (LRR) Domain | Q7ZTG5.fasta | Q7ZTG5 | 843 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2232 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | chorioamniotic membranes | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2232 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | chorioamniotic membranes | Leucine-rich Repeat (LRR) Domain | O60603.fasta | O60603 | 784 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2233 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 3 (TLR3) | Toll-like receptor (TLR) | Human | luminal epithelial cells of the prostrate | Leucine-rich Repeat (LRR) Domain | O15455.fasta | O15455 | 904 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2233 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 3 (TLR3) | Toll-like receptor (TLR) | Human | luminal epithelial cells of the prostrate | Leucine-rich Repeat (LRR) Domain | O15455.fasta | O15455 | 904 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2234 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 8 (TLR8) | Toll-like receptor (TLR) | Human | luminal epithelial cells of the prostrate | Leucine-rich Repeat (LRR) Domain | Q9NR97.fasta | Q9NR97 | 1041 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2234 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 8 (TLR8) | Toll-like receptor (TLR) | Human | luminal epithelial cells of the prostrate | Leucine-rich Repeat (LRR) Domain | Q9NR97.fasta | Q9NR97 | 1041 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2235 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Horse | cell surface and in the cytoplasm of bronchiolar epithelial cells | Leucine-rich Repeat (LRR) Domain | Q2EEY0.fasta | Q2EEY0 | 1031 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2235 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 9 (TLR9) | Toll-like receptor (TLR) | Horse | cell surface and in the cytoplasm of bronchiolar epithelial cells | Leucine-rich Repeat (LRR) Domain | Q2EEY0.fasta | Q2EEY0 | 1031 | NA | NA | 29330675 | 2017 | Pubchem_assay |
| PRRID_2236 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29264745 | 2017 | Pubchem_assay |
| PRRID_2236 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29264745 | 2017 | Pubchem_assay |
| PRRID_2237 | Lipopolysaccharide (LPS) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | cell surface | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29263932 | 2017 | Pubchem_assay |
| PRRID_2237 | Lipopolysaccharide (LPS) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | cell surface | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29263932 | 2017 | Pubchem_assay |
| PRRID_2238 | Lipopolysaccharide (LPS) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Platelets | leucine-rich-repeat (LRR) , nucleotide-binding domain (NBD), caspase activation and recruitment domain (CARD) | O00206.fasta | O00206 | 839 | release soluble factors to modulate the immune response | NA | 29220594 | 2017 | Pubchem_assay |
| PRRID_2238 | Lipopolysaccharide (LPS) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Platelets | leucine-rich-repeat (LRR) , nucleotide-binding domain (NBD), caspase activation and recruitment domain (CARD) | O00206.fasta | O00206 | 839 | release soluble factors to modulate the immune response | NA | 29220594 | 2017 | Pubchem_assay |
| PRRID_2239 | Lipopolysaccharide (LPS) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Causes Mastitis, an infection of the mammary gland | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | mammary tissue | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29113806 | 2017 | Pubchem_assay |
| PRRID_2239 | Lipopolysaccharide (LPS) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Causes Mastitis, an infection of the mammary gland | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | mammary tissue | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29113806 | 2017 | Pubchem_assay |
| PRRID_2240 | Lipopolysaccharide (LPS) Click for more detail | E. coli K12(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | anti- inflammatory activity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | U937 cells | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29113797 | 2017 | Pubchem_assay |
| PRRID_2240 | Lipopolysaccharide (LPS) Click for more detail | E. coli K12(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | anti- inflammatory activity | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | U937 cells | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29113797 | 2017 | Pubchem_assay |
| PRRID_2241 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Urinary Tract infection | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | bladder and uroepithelial cells | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29066305 | 2017 | Pubchem_assay |
| PRRID_2241 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Urinary Tract infection | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | bladder and uroepithelial cells | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29066305 | 2017 | Pubchem_assay |
| PRRID_2242 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2242 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | NA | O00206.fasta | O00206 | 839 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2243 | Lipopolysaccharide (LPS) Click for more detail | Gram negative bacteria(Leptospira spp.) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | infection | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | ELISA | 29038956 | 2017 | Pubchem_assay |
| PRRID_2243 | Lipopolysaccharide (LPS) Click for more detail | Gram negative bacteria(Leptospira spp.) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | infection | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | ELISA | 29038956 | 2017 | Pubchem_assay |
| PRRID_2244 | Lipopolysaccharide (LPS) Click for more detail | B. subtilis and E. coli(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | OfbGRP3 | Gastrin-releasing peptide receptor (GRP) | O. furnacalis larvae | NA | two N-linked glycosylation sites, two O-linked glycosylation sites, the putative cell adhesive site (QGD), a potential kinase C phosphorylation site (SAR) and a glycosyl hydrolase family 16 domain. | NA | NA | NA | NA | NA | 29032241 | 2017 | NA |
| PRRID_2244 | Lipopolysaccharide (LPS) Click for more detail | B. subtilis and E. coli(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | OfbGRP3 | Gastrin-releasing peptide receptor (GRP) | O. furnacalis larvae | NA | two N-linked glycosylation sites, two O-linked glycosylation sites, the putative cell adhesive site (QGD), a potential kinase C phosphorylation site (SAR) and a glycosyl hydrolase family 16 domain. | NA | NA | NA | NA | NA | 29032241 | 2017 | NA |
| PRRID_2245 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Formation of a complex between PI 3-kinase and MyD88, induction of IL-1β, TNF-α and macrophage inflammatory protein (MIP)-2, induce proinflammatory cytokine production through NF-KB signaling , Functional maturation of mouse macrophages, induction of TNF-α by Human Monocyte Cultures, Production of major proinflammatory cytokines such as IL-1, IL-6, or TNF-α; activate DC and promote the development of Th-like responses | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Mouse macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2245 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Formation of a complex between PI 3-kinase and MyD88, induction of IL-1β, TNF-α and macrophage inflammatory protein (MIP)-2, induce proinflammatory cytokine production through NF-KB signaling , Functional maturation of mouse macrophages, induction of TNF-α by Human Monocyte Cultures, Production of major proinflammatory cytokines such as IL-1, IL-6, or TNF-α; activate DC and promote the development of Th-like responses | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Mouse macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2246 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | rPtCTL-2 | C type Lectin (CTL/CLR) | Portunus trituberculatus | NA | Carbohydrate recognition Domain | NA | NA | NA | recognize nonself invaders and also work as an opsonin to eliminate invaders | PAMPs binding assay | 28916358 | 2017 | NA |
| PRRID_2246 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | rPtCTL-2 | C type Lectin (CTL/CLR) | Portunus trituberculatus | NA | Carbohydrate recognition Domain | NA | NA | NA | recognize nonself invaders and also work as an opsonin to eliminate invaders | PAMPs binding assay | 28916358 | 2017 | NA |
| PRRID_2247 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | PmToll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Pinctada fucata martensii | Hemocytes | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | play a vital role in the induction of innate immunity and is therefore associated with allograft immunity in the pearl oyster P. fucata martensii. | NA | 28893645 | 2017 | NA |
| PRRID_2247 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | PmToll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Pinctada fucata martensii | Hemocytes | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | play a vital role in the induction of innate immunity and is therefore associated with allograft immunity in the pearl oyster P. fucata martensii. | NA | 28893645 | 2017 | NA |
| PRRID_2248 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | CgLRRIG-1 | Pattern recognition receptor (PRR) | oyster Crassostrea gigas | Muscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas. | Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domain | NA | NA | NA | immune effectors or pro-inflammatory factors as well as PRRs in oyster. | PAMPs binding assay | 28889011 | 2017 | NA |
| PRRID_2248 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | CgLRRIG-1 | Pattern recognition receptor (PRR) | oyster Crassostrea gigas | Muscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas. | Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domain | NA | NA | NA | immune effectors or pro-inflammatory factors as well as PRRs in oyster. | PAMPs binding assay | 28889011 | 2017 | NA |
| PRRID_2249 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | CgLRRIG-2 | Pattern recognition receptor (PRR) | oyster Crassostrea gigas | Muscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas. | Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domain | NA | NA | NA | immune effectors or pro-inflammatory factors as well as PRRs in oyster. | PAMPs binding assay | 28889011 | 2017 | NA |
| PRRID_2249 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | CgLRRIG-2 | Pattern recognition receptor (PRR) | oyster Crassostrea gigas | Muscle, gill, hepatopancreas, mantle, gonad and hemocytes with the highest expression level in hepatopancreas. | Leucine-rich repeat (LRR) domain and immunoglobulin (Ig) domain | NA | NA | NA | immune effectors or pro-inflammatory factors as well as PRRs in oyster. | PAMPs binding assay | 28889011 | 2017 | NA |
| PRRID_2250 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | SSc5D | Scavenger receptor (SR) | NA | NA | SRCR-Containing N-Terminal Domain | NA | NA | NA | tissue homeostasis, host defence reactivity and regulation of immune reactions and inflammation, | NA | 28878773 | 2017 | NA |
| PRRID_2250 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | SSc5D | Scavenger receptor (SR) | NA | NA | SRCR-Containing N-Terminal Domain | NA | NA | NA | tissue homeostasis, host defence reactivity and regulation of immune reactions and inflammation, | NA | 28878773 | 2017 | NA |
| PRRID_2251 | Lipopolysaccharide (LPS) Click for more detail | V. harveyi (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | rFmLC4 | Pattern recognition receptor (PRR) | aquatic shrimp | Hepatopancreas | CRD and Ca+ binding | NA | NA | NA | contribute a role in the shrimp immune defense through its specific binding and agglutination. | ELISA | 28844966 | 2017 | NA |
| PRRID_2251 | Lipopolysaccharide (LPS) Click for more detail | V. harveyi (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | rFmLC4 | Pattern recognition receptor (PRR) | aquatic shrimp | Hepatopancreas | CRD and Ca+ binding | NA | NA | NA | contribute a role in the shrimp immune defense through its specific binding and agglutination. | ELISA | 28844966 | 2017 | NA |
| PRRID_2252 | Lipopolysaccharide (LPS) Click for more detail | S. aureus (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Increases expression of Bmintegrin β3 . | Bmintegrin β3 | Integrins | Bombyx mori | Hemocytes | NA | NA | NA | NA | Bmintegrin β3 knockdown promoted PPO1, PPO2, BAEE, SPH78, SPH125, and SPH127 expression and accelerated the melanization process. | qRT-PCR | 28826989 | 2017 | NA |
| PRRID_2252 | Lipopolysaccharide (LPS) Click for more detail | S. aureus (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Increases expression of Bmintegrin β3 . | Bmintegrin β3 | Integrins | Bombyx mori | Hemocytes | NA | NA | NA | NA | Bmintegrin β3 knockdown promoted PPO1, PPO2, BAEE, SPH78, SPH125, and SPH127 expression and accelerated the melanization process. | qRT-PCR | 28826989 | 2017 | NA |
| PRRID_2253 | Lipopolysaccharide (LPS) Click for more detail | Pseudomonas aeruginosa (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | stimulation of THP-1 macrophages | MUC1 mucin | Pattern recognition receptor (PRR) | Human | surface of epithelial cells and some hematopoietic cells | NA | A0A087X2A4.fasta | A0A087X2A4 | 484 | phagocytic activity and cytokine production | ELISA | 28822766 | 2017 | Pubchem_assay |
| PRRID_2253 | Lipopolysaccharide (LPS) Click for more detail | Pseudomonas aeruginosa (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | stimulation of THP-1 macrophages | MUC1 mucin | Pattern recognition receptor (PRR) | Human | surface of epithelial cells and some hematopoietic cells | NA | A0A087X2A4.fasta | A0A087X2A4 | 484 | phagocytic activity and cytokine production | ELISA | 28822766 | 2017 | Pubchem_assay |
| PRRID_2254 | Lipopolysaccharide (LPS) Click for more detail | Pseudomonas aeruginosa (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | stimulation of THP-1 macrophages | MUC1 mucin | Pattern recognition receptor (PRR) | Mice | surface of epithelial cells and some hematopoietic cells | NA | Q02496.fasta | Q02496 | 630 | phagocytic activity and cytokine production | ELISA | 28822766 | 2017 | Pubchem_assay |
| PRRID_2254 | Lipopolysaccharide (LPS) Click for more detail | Pseudomonas aeruginosa (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | stimulation of THP-1 macrophages | MUC1 mucin | Pattern recognition receptor (PRR) | Mice | surface of epithelial cells and some hematopoietic cells | NA | Q02496.fasta | Q02496 | 630 | phagocytic activity and cytokine production | ELISA | 28822766 | 2017 | Pubchem_assay |
| PRRID_2255 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Brain | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | mRNA ‚Üë in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2255 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Brain | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | mRNA ‚Üë in aging | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2256 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Brain | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | mRNA ‚Üë in plaque- associated brain tissue of AD model mice | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2256 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Brain | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | mRNA ‚Üë in plaque- associated brain tissue of AD model mice | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2257 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | brain(hippocampus, superior frontal gyrus, post-central gyrus) | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | mRNA ‚Üë in aging and AD | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2257 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | brain(hippocampus, superior frontal gyrus, post-central gyrus) | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | mRNA ‚Üë in aging and AD | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2258 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Microglia | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | involved in both amyloid-β uptake and inflammatory cytokine production | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2258 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Microglia | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | involved in both amyloid-β uptake and inflammatory cytokine production | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2259 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | microglia (mouse striatum) | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | TLR4 knockout: neuroprotective in ischemia | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2259 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | microglia (mouse striatum) | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | TLR4 knockout: neuroprotective in ischemia | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2260 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | neurons (mouse cortex) | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | protein ‚Üë, proapoptotic in ischemia | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2260 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | neurons (mouse cortex) | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | protein ‚Üë, proapoptotic in ischemia | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2261 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2261 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Rat | rat brain (vasculature) | Leucine-rich Repeat (LRR) Domain | Q9QX05.fasta | Q9QX05 | 835 | protein ‚Üë, activation in ischemic stroke | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2262 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | primary mouse astrocytes | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | activation in response to α-synuclein | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2262 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | primary mouse astrocytes | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | activation in response to α-synuclein | NA | 28801521 | 2017 | Pubchem_assay |
| PRRID_2263 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Bind to Ficolins and stimulate innate immunity. | MnFico1 | Pattern recognition receptor (PRR) | Macrobrachium nipponense | Gills | signal peptide and a fibrinogen-related domain. | NA | NA | NA | regulate the expression of AMP genes. | qRT-PCR | 28764985 | 2017 | NA |
| PRRID_2263 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Bind to Ficolins and stimulate innate immunity. | MnFico1 | Pattern recognition receptor (PRR) | Macrobrachium nipponense | Gills | signal peptide and a fibrinogen-related domain. | NA | NA | NA | regulate the expression of AMP genes. | qRT-PCR | 28764985 | 2017 | NA |
| PRRID_2264 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Bind to Ficolins and stimulate innate immunity. | MnFico2 | Pattern recognition receptor (PRR) | Macrobrachium nipponense | Gills | signal peptide and a fibrinogen-related domain. | NA | NA | NA | regulate the expression of AMP genes. | qRT-PCR | 28764985 | 2017 | NA |
| PRRID_2264 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Bind to Ficolins and stimulate innate immunity. | MnFico2 | Pattern recognition receptor (PRR) | Macrobrachium nipponense | Gills | signal peptide and a fibrinogen-related domain. | NA | NA | NA | regulate the expression of AMP genes. | qRT-PCR | 28764985 | 2017 | NA |
| PRRID_2265 | Lipopolysaccharide (LPS) Click for more detail | P. gulae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Causes inflammation and activation of TLR2. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUN7.fasta | Q9QUN7 | 784 | activate NF-κB. | NA | 28630066 | 2017 | Pubchem_assay |
| PRRID_2265 | Lipopolysaccharide (LPS) Click for more detail | P. gulae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Causes inflammation and activation of TLR2. | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Mice | Macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUN7.fasta | Q9QUN7 | 784 | activate NF-κB. | NA | 28630066 | 2017 | Pubchem_assay |
| PRRID_2266 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Activation of CLRs. | rCaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2266 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Activation of CLRs. | rCaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2267 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Activation of MjSRC. | MjSRC | Scavenger receptor (SR) | Marsupenaeus japonicus | Hemocytes | CCP and MAM domains of MjSRC | A0A1L2DC21.fasta | A0A1L2DC21 | 692 | phagocytosis of pathogenic microbes by macrophage and dendritic cell | Polysacharides binding assay | 28602682 | 2017 | Pubchem_assay |
| PRRID_2267 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Activation of MjSRC. | MjSRC | Scavenger receptor (SR) | Marsupenaeus japonicus | Hemocytes | CCP and MAM domains of MjSRC | A0A1L2DC21.fasta | A0A1L2DC21 | 692 | phagocytosis of pathogenic microbes by macrophage and dendritic cell | Polysacharides binding assay | 28602682 | 2017 | Pubchem_assay |
| PRRID_2268 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | CqToll | Toll-like receptor (TLR) | Cherax quadricarinatus | Hemocytes | extracellular domain of 19 leucine-rich repeats residues, a transmembrane domain and an intracellular domain of 138 amino acids. | NA | NA | NA | CqToll involved in anti-WSSV response | qRT-PCR | 28479346 | 2017 | NA |
| PRRID_2268 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | CqToll | Toll-like receptor (TLR) | Cherax quadricarinatus | Hemocytes | extracellular domain of 19 leucine-rich repeats residues, a transmembrane domain and an intracellular domain of 138 amino acids. | NA | NA | NA | CqToll involved in anti-WSSV response | qRT-PCR | 28479346 | 2017 | NA |
| PRRID_2269 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | BjLRP | Low density lipoprotein receptor-related protein (LRP) | B. japonicum | gill, muscle, notochord and testis | LY-EGF-CRD- EGF-CRD | NA | NA | NA | phagocytosis of apoptotic cells | qRT-PCR | 28400271 | 2017 | NA |
| PRRID_2269 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | BjLRP | Low density lipoprotein receptor-related protein (LRP) | B. japonicum | gill, muscle, notochord and testis | LY-EGF-CRD- EGF-CRD | NA | NA | NA | phagocytosis of apoptotic cells | qRT-PCR | 28400271 | 2017 | NA |
| PRRID_2270 | Lipopolysaccharide (LPS) Click for more detail | Vibrio (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | Leulectin | Pattern recognition receptor (PRR) | Marsupenaeus japonicus | Hemocytes | CTLD | NA | NA | NA | Hemocytic Phagocytosis | Pull- down and far-Western assays | 28258197 | 2017 | NA |
| PRRID_2270 | Lipopolysaccharide (LPS) Click for more detail | Vibrio (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | Leulectin | Pattern recognition receptor (PRR) | Marsupenaeus japonicus | Hemocytes | CTLD | NA | NA | NA | Hemocytic Phagocytosis | Pull- down and far-Western assays | 28258197 | 2017 | NA |
| PRRID_2271 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | rBjAVIDIN1 | Pattern recognition receptor (PRR) | B. japonicum | Hemocytes | NA | NA | NA | NA | phagocytosis of bacteria by macrophages, | qRT-PCR | 28069430 | 2017 | NA |
| PRRID_2271 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | rBjAVIDIN1 | Pattern recognition receptor (PRR) | B. japonicum | Hemocytes | NA | NA | NA | NA | phagocytosis of bacteria by macrophages, | qRT-PCR | 28069430 | 2017 | NA |
| PRRID_2272 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | rBjAVIDIN1 | Pattern recognition receptor (PRR) | B. japonicum | Hemocytes | NA | NA | NA | NA | phagocytosis of bacteria by macrophages, | qRT-PCR | 28069430 | 2017 | NA |
| PRRID_2272 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Immunostimulant | rBjAVIDIN1 | Pattern recognition receptor (PRR) | B. japonicum | Hemocytes | NA | NA | NA | NA | phagocytosis of bacteria by macrophages, | qRT-PCR | 28069430 | 2017 | NA |
| PRRID_2273 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | AcTREM1 | Pattern recognition receptor (PRR) | NA | cell-surface receptor | NA | NA | NA | NA | NA | NA | 28344169 | 2017 | NA |
| PRRID_2273 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | AcTREM1 | Pattern recognition receptor (PRR) | NA | cell-surface receptor | NA | NA | NA | NA | NA | NA | 28344169 | 2017 | NA |
| PRRID_2274 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | AcTREM2 | Pattern recognition receptor (PRR) | NA | cell-surface receptor | NA | NA | NA | NA | NA | NA | 28344169 | 2017 | NA |
| PRRID_2274 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | AcTREM2 | Pattern recognition receptor (PRR) | NA | cell-surface receptor | NA | NA | NA | NA | NA | NA | 28344169 | 2017 | NA |
| PRRID_2275 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2275 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | NA | NA | 28063015 | 2017 | NA |
| PRRID_2276 | Lipopolysaccharide (LPS) Click for more detail | Vibrio harveyi (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Pathogenic infection | FmLC5 | C type Lectin (CTL/CLR) | Fenneropenaeus merguiensis | hemocytes | two similar carbohydrate recognition domains (CRDs), each CRD contains a Ca2+ binding site-2 and a QPD motif specific for galactose-binding | NA | NA | NA | NA | qRT-PCR | 28958586 | 2017 | NA |
| PRRID_2276 | Lipopolysaccharide (LPS) Click for more detail | Vibrio harveyi (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Pathogenic infection | FmLC5 | C type Lectin (CTL/CLR) | Fenneropenaeus merguiensis | hemocytes | two similar carbohydrate recognition domains (CRDs), each CRD contains a Ca2+ binding site-2 and a QPD motif specific for galactose-binding | NA | NA | NA | NA | qRT-PCR | 28958586 | 2017 | NA |
| PRRID_2277 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rPtCTL-2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28288910 | 2017 | NA |
| PRRID_2277 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rPtCTL-2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28288910 | 2017 | NA |
| PRRID_2279 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27818342 | 2017 | NA |
| PRRID_2279 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27818342 | 2017 | NA |
| PRRID_2281 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | MrCTL | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27620819 | 2017 | NA |
| PRRID_2281 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | MrCTL | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27620819 | 2017 | NA |
| PRRID_2283 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | PcFBN1 | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 27417229 | 2017 | NA |
| PRRID_2283 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | NA | PcFBN1 | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 27417229 | 2017 | NA |