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| ID | PMID | YEAR | Sequence | Name | Length | N-ter MOD | C-ter MOD | Linear/Cyclic | Chirality | Chem-MOD | Origin | Nature | Incubation Time | Concentration | Half Life | Units Half Life | Protease | Assay | Test Sample | Vivo/Vitro | Reference | Patent No. | Activity |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 20844765 | 2010 | Lfc1 | 6 | Free | Free | Linear | L | None | Bovine lactoferricin | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=60μM for E.coli | |||
| 20844765 | 2010 | Lfc1 | 6 | Free | Free | Linear | L | None | Bovine lactoferricin | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=30μM for S. aureus | |||
| 20844765 | 2010 | Lfc1 | 6 | Free | Free | Linear | L | None | Bovine lactoferricin | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5 μM for B. subtilis | |||
| 20844765 | 2010 | Com1 | 6 | Free | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=60μM for E.coli | |||
| 20844765 | 2010 | Com1 | 6 | Free | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for S. aureus | |||
| 20844765 | 2010 | Com1 | 6 | Free | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=1.9 μM for B. subtilis | |||
| 20844765 | 2010 | Lfc2 | 6 | Free | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=15μM for E.coli | |||
| 20844765 | 2010 | Lfc2 | 6 | Free | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=15μM for S. aureus | |||
| 20844765 | 2010 | Lfc2 | 6 | Free | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=1.9μM for B. subtilis | |||
| 20844765 | 2010 | Com2 | 6 | Free | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=30μM for E.coli | |||
| 20844765 | 2010 | Com2 | 6 | Free | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=30μM for S. aureus | |||
| 20844765 | 2010 | Com2 | 6 | Free | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | <30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=0.9 μM for B. subtilis | |||
| 20844765 | 2010 | Lfc3 | 6 | Acetylation | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~60 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=120μM for E.coli | |||
| 20844765 | 2010 | Lfc3 | 6 | Acetylation | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~60 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99>120μM for S. aureus | |||
| 20844765 | 2010 | Lfc3 | 6 | Acetylation | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~60 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=60 μM for B. subtilis | |||
| 20844765 | 2010 | Com3 | 6 | Acetylation | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~60 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=120μM for E.coli | |||
| 20844765 | 2010 | Com3 | 6 | Acetylation | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~60 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=30μM for S. aureus | |||
| 20844765 | 2010 | Com3 | 6 | Acetylation | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~60 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for B. subtilis | |||
| 20844765 | 2010 | Lfc4 | 6 | Acetylation | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~90 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=15μM for E.coli | |||
| 20844765 | 2010 | Lfc4 | 6 | Acetylation | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~90 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=60μM for S. aureus | |||
| 20844765 | 2010 | Lfc4 | 6 | Acetylation | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~90 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=3.8μM for B. subtilis | |||
| 20844765 | 2010 | Com4 | 6 | Acetylation | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~90 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for E.coli | |||
| 20844765 | 2010 | Com4 | 6 | Acetylation | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~90 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for S. aureus | |||
| 20844765 | 2010 | Com4 | 6 | Acetylation | Amidation | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~90 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=1.9 μM for B. subtilis | |||
| 20844765 | 2010 | Lfc5 | 6 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 24 hours | 5 µM | ~24 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for E.coli | |||
| 20844765 | 2010 | Lfc5 | 6 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 24 hours | 5 µM | ~24 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for S. aureus | |||
| 20844765 | 2010 | Lfc5 | 6 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 24 hours | 5 µM | ~24 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=1.9μM for B. subtilis | |||
| 20844765 | 2010 | Com5 | 6 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 24 hours | 5 µM | ~24 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=30μM for E.coli | |||
| 20844765 | 2010 | Com5 | 6 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 24 hours | 5 µM | ~24 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for S. aureus | |||
| 20844765 | 2010 | Com5 | 6 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 24 hours | 5 µM | ~24 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99 ‰¤ 0.45μM for B. subtilis | |||
| 20844765 | 2010 | Lfc6 | 8 | Free | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~1.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=15μM for E.coli | |||
| 20844765 | 2010 | Lfc6 | 8 | Free | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~1.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=3.8μM for S. aureus | |||
| 20844765 | 2010 | Lfc6 | 8 | Free | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | ~1.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=0.9μM for B. subtilis | |||
| 20844765 | 2010 | Com6 | 8 | Free | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 6.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=3.8μM for E.coli | |||
| 20844765 | 2010 | Com6 | 8 | Free | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 6.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=0.9μM for S. aureus | |||
| 20844765 | 2010 | Com6 | 8 | Free | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 6.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=0.9μM for B. subtilis | |||
| 20844765 | 2010 | Lfc7 | 11 | Free | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | >30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=15μM for E.coli | |||
| 20844765 | 2010 | Lfc7 | 11 | Free | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | >30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=7.5μM for S. aureus | |||
| 20844765 | 2010 | Lfc7 | 11 | Free | Free | Linear | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | >30 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=0.9μM for B. subtilis | |||
| 20844765 | 2010 | Com7 | 8 | Acetylation | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 6.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=30μM for E.coli | |||
| 20844765 | 2010 | Com7 | 8 | Acetylation | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 6.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=1.9μM for S. aureus | |||
| 20844765 | 2010 | Com7 | 8 | Acetylation | Amidation | Cyclic (C1-C8) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 6.5 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99 ‰¤ 0.45μM for B. subtilis | |||
| 20844765 | 2010 | Lfc8 | 11 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 110 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=3.8 μM for E.coli | |||
| 20844765 | 2010 | Lfc8 | 11 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 110 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=15μM for S. Aureus | |||
| 20844765 | 2010 | Lfc8 | 11 | Free | Free | Cyclic (head-to-tail backbone cyclization) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 110 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99 ‰¤ 0.45μM for B. subtilis | |||
| 20844765 | 2010 | Lfc9 | 13 | Free | Amidation | Cyclic (C1-C13) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 110 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99=1.9 μM for E.coli | |||
| 20844765 | 2010 | Lfc9 | 13 | Free | Amidation | Cyclic (C1-C13) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 110 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99 ‰¤ 0.45μM for S. Aureus | |||
| 20844765 | 2010 | Lfc9 | 13 | Free | Amidation | Cyclic (C1-C13) | L | None | Synthetic | Antimicrobial | 9 hours | 5 µM | 110 | Human serum proteases | RP-HPLC | Human serum | in vitro | None | None | LD99.99 ‰¤ 0.45μM for B. subtilis | |||
| 20382695 | 2010 | Taspoglutide | 30 | Free | Amidation | Linear | L | Aib--Aminoisobutyric acid | Derivative of glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 9.8 | Rat plasma protease | RP-HPLC | Rat plasma | in vitro | 14759771 | None | EC50=0.06nM for stimulating cAMP production | |||
| 20382695 | 2010 | hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | None | Glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 50 | Rat plasma protease | RP-HPLC | Rat plasma | in vitro | 14759771 | None | EC50=0.08nM for stimulating cAMP production | |||
| 20418955 | 2010 | Gcg-XTEN 288 | 319 | Free | XTEN | Linear | L | None | Glucagon derivative | Regulate blood glucose | Not mentioned | 12 nmol/kg | 9 | Cynomolgus monkey plasma proteases | Sandwich ELISA | Injected subcutaneouly into cynomolgus monkeys | in vivo | None | None | Elevated blood glucose levels for 10 €“12 hours | |||
| 20418955 | 2010 | Gcg-XTEN 144 | 175 | Free | XTEN | Linear | L | None | Glucagon derivative | Regulate blood glucose | Not mentioned | 12 nmol/kg | 8 to 10 | Cynomolgus monkey plasma proteases | Sandwich ELISA | Injected subcutaneouly into cynomolgus monkeys | in vivo | None | None | Not reported | |||
| 20418955 | 2010 | Glucagon | 29 | Free | Free | Linear | L | None | Glucagon | Regulate blood glucose | Not mentioned | Not mentioned | <10 | Not reported | Not mentioned | Not reported | in vivo | None | None | Elevated blood glucose levels for <2 hours | |||
| 21244372 | 2010 | Exenatide | 39 | Free | Amidation | Linear | L | None | Synthetic version of the 39-amino-acid peptide originally isolated from the saliva of the gila monster lizard | Regulate blood glucose | Not mentioned | 5 µg ·mL-1 ·kg-1 | 1.5 to 4 | Rat plasma proteases | ELISA | Intravenously injected into Sprague-Dawley rats at a dose of 5 µg ·mL-1 ·kg-1 | in vivo | None | None | EC50 of 2.3nM for stimulation of intracellular cAMP in PC12 cells | |||
| 21244372 | 2010 | PB-105 (ExC39) | 39 | Free | Amidation | Linear | L | None | Analogue of exenatide | Regulate blood glucose | Not mentioned | 5 µg ·mL-1 ·kg-1 | 2.9 ±0.1 | Rat plasma proteases | ELISA | Intravenously injected into Sprague-Dawley rats at a dose of 5 µg ·mL-1 ·kg-1 | in vivo | None | None | EC50 of 1.4nM for stimulation of intracellular cAMP in PC12 cells | |||
| 21244372 | 2010 | PB-110 (ExC39PEG5kDa) | 39 | Free | Amidation | Linear | L | 5 kDa PEG at Cys at 39th position | Analogue of exenatide | Regulate blood glucose | Not mentioned | 5 µg ·mL-1 ·kg-1 | 6.1 ±0.8 | Rat plasma proteases | ELISA | Intravenously injected into Sprague-Dawley rats at a dose of 5 µg ·mL-1 ·kg-1 | in vivo | None | None | EC50 of 1.3nM for stimulation of intracellular cAMP in PC12 cells | |||
| 21244372 | 2010 | PB-106 (ExC39PEG20kDa) | 39 | Free | Amidation | Linear | L | 20 kDa PEG at Cys at 39th position | Analogue of exenatide | Regulate blood glucose | Not mentioned | 5 µg ·mL-1 ·kg-1 | 49.4 ±7.7 | Rat plasma proteases | ELISA | Intravenously injected into Sprague-Dawley rats at a dose of 5 µg ·mL-1 ·kg-1 | in vivo | None | None | EC50 of 1.2nM for stimulation of intracellular cAMP in PC12 cells | |||
| 21244372 | 2010 | PB-107 (ExC39PEG30kDa) | 39 | Free | Amidation | Linear | L | 30 kDa PEG at Cys at 39th position | Analogue of exenatide | Regulate blood glucose | Not mentioned | 5 µg ·mL-1 ·kg-1 | 70.5 ±2.6 | Rat plasma proteases | ELISA | Intravenously injected into Sprague-Dawley rats at a dose of 5 µg ·mL-1 ·kg-1 | in vivo | None | None | EC50 of 14.2nM for stimulation of intracellular cAMP in PC12 cells | |||
| 21244372 | 2010 | PB-108 (ExC39PEG40kDa) | 39 | Free | Amidation | Linear | L | 40 kDa PEG at Cys at 39th position | Analogue of exenatide | Regulate blood glucose | Not mentioned | 5 µg ·mL-1 ·kg-1 | 76.4 ±7.4 | Rat plasma proteases | ELISA | Intravenously injected into Sprague-Dawley rats at a dose of 5 µg ·mL-1 ·kg-1 | in vivo | None | None | EC50 of 114.1nM for stimulation of intracellular cAMP in PC12 cells | |||
| 21114599 | 2010 | hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | None | Glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 0.9 ±0.1 | Rat plasma proteases | HPLC | Rat plasma | in vitro | 14759771 | None | EC50=0.08 ±0.03nM for cAMP stimulation | |||
| 21114599 | 2010 | [Aib8]hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | Aib--Aminoisobutyric acid | Analogue of glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 5.9 ±1.0 | Rat plasma proteases | HPLC | Rat plasma | in vitro | 14759771 | None | EC50=0.29 ±0.22nM for cAMP stimulation | |||
| 21114599 | 2010 | [Aib35]hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | Aib--Aminoisobutyric acid | Analogue of glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 2.0 ±0.3 | Rat plasma proteases | HPLC | Rat plasma | in vitro | 14759771 | None | EC50=0.05 ±0.01nM for cAMP stimulation | |||
| 21114599 | 2010 | [Aib8,35]hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | Aib--Aminoisobutyric acid | Analogue of glucagon like peptide1 | Regulate blood glucose | Not mentioned | Not mentioned | 20.4 ±1.8 | Rat plasma proteases | HPLC | Rat plasma | in vitro | 14759771 | None | EC50=0.06 ±0.04nM for cAMP stimulation | |||
| 21114599 | 2010 | hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | None | Glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 10.3 | Human plasma proteases | HPLC | Human plasma | in vitro | 14759771 | None | EC50=0.08 ±0.03nM for cAMP stimulation | |||
| 21114599 | 2010 | [Aib8]hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | Aib--Aminoisobutyric acid | Analogue of glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 12.1 | Human plasma proteases | HPLC | Human plasma | in vitro | 14759771 | None | EC50=0.29 ±0.22nM for cAMP stimulation | |||
| 21114599 | 2010 | [Aib35]hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | Aib--Aminoisobutyric acid | Analogue of glucagon like peptide-1 | Regulate blood glucose | Not mentioned | Not mentioned | 18.4 | Human plasma proteases | HPLC | Human plasma | in vitro | 14759771 | None | EC50=0.05 ±0.01nM for cAMP stimulation | |||
| 21114599 | 2010 | [Aib8,35]hGLP-1(7-36)NH2 | 30 | Free | Amidation | Linear | L | Aib--Aminoisobutyric acid | Analogue of glucagon like peptide1 | Regulate blood glucose | Not mentioned | Not mentioned | 66 | Human plasma proteases | HPLC | Human plasma | in vitro | 14759771 | None | EC50=0.06 ±0.04nM for cAMP stimulation | |||
| 20587645 | 2010 | HM-3 | 16 | Free | Free | Linear | L | None | Derivative of endostatin | Anti-angiogenetic | Not mentioned | Not mentioned | 10 to 27 | SD rat plasma proteases | RP-HPLC | SD rat plasma | in vitro | http://pubs.rsc.org/En/content/articlepdf/2014/tb/ | None | 39.68% inhibitory effect on mouse tumors | |||
| 20587645 | 2010 | PEG20k-HM-3 | 16 | Methoxy-polyethylene glycol-Succinimidyl Carbonate (SC-mPEG, molecular weight 20 kDa, named SC-mPEG20k ) | Free | Linear | L | None | HM-3 analogue | Anti-angiogenetic | Not mentioned | Not mentioned | >132 | SD rat plasma proteases | RP-HPLC | SD rat plasma | in vitro | http://pubs.rsc.org/En/content/articlepdf/2014/tb/ | None | 44.35% inhibitory effect on mouse tumors | |||
| 20587645 | 2010 | mPEG-ALD10k-HM-3 | 16 | Methoxy-polyethylene glycolPEG-aldehyde (mPEG-ALD10k ) | Free | Linear | L | None | HM-3 analogue | Anti-angiogenetic | Not mentioned | Not mentioned | 162.08 ±36.57 | Proteases in chorioallantoic membrane of chick embryo | RP-HPLC | Chorioallantoic membrane of chick embryo | in vivo | http://pubs.rsc.org/En/content/articlepdf/2014/tb/ | None | Dramatically inhibits angiogenesis on the chorioallantoic membrane of chick embryo | |||
| 20593470 | 2010 | Peptide 1 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 0.9 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 2 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 1.1 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 3 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 0.7 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 4 | 41 | Free | Amidation | Linear | Mix | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 0.9 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 5 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 4.7 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 6 | 41 | Free | Amidation | Linear | Mix | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 5.1 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 7 | 41 | Free | Amidation | Linear | L | tBu=tertiary butyl | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | >168 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 8 | 41 | Free | Amidation | Linear | L | PhG=phenylglycine | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 0.5 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 9 | 41 | Free | Amidation | Linear | L | Aib=α-aminoisobutyric acid | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 0.8 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 10 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 20.4 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 11 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 2.5 | None | HPLC | PBS | in vitro | None | None | EC50=0.23 ±0.10nM | |||
| 20593470 | 2010 | Peptide 12 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 2.8 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 13 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 2.4 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 14 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 33.3 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 15 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 7.7 | None | HPLC | PBS | in vitro | None | None | EC50=0.77 ±0.25 | |||
| 20593470 | 2010 | Peptide 16 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | >168 | None | HPLC | PBS | in vitro | None | None | Not reported | |||
| 20593470 | 2010 | Peptide 17 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 50.6 | None | HPLC | PBS | in vitro | None | None | EC50=0.04 ±0.06nM | |||
| 20593470 | 2010 | Peptide 18 | 41 | Free | Amidation | Linear | L | None | Synthetic dipeptide extended GLP-analogs | Regulate blood glucose | 168 hours | Not mentioned | 64 | None | HPLC | PBS | in vitro | None | None | EC50=2.07 ±0.41nM | |||
| 20560643 | 2009 | Peptide 1 (TY027) | 8 | Free | NH-3,5-Bzl(CF3)2 | Linear | Mix | None | Synthetic | Opioid receptor agonist | 24 hours | Not mentioned | 4.8 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | IC50=15 ±2nM for MVD | |||
| 20560643 | 2009 | Peptide 2 | 8 | Free | NH-3,5-Bzl(CF3)2 | Linear | Mix | Nle=norleucine | Synthetic analogues of TY027 | Opioid receptor agonist | 24 hours | Not mentioned | >6 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | IC50=14 ±1.6nM for MVD | |||
| 20560643 | 2009 | Peptide 5 | 8 | Free | NH-3,5-Bzl(CF3)2 | Linear | Mix | Nle=norleucine, O-β-glucosylated serine | Synthetic analogues of TY027 | Opioid receptor agonist | 24 hours | Not mentioned | >6 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | IC50=13 ±5.8nM for MVD | |||
| 20560643 | 2009 | Peptide 6 | 9 | Free | NH-3,5-Bzl(CF3)2 | Linear | Mix | Nle=norleucine, O-β-glucosylated serine | Synthetic analogues of TY027 | Opioid receptor agonist | 24 hours | Not mentioned | >24 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | IC50=17 ±4.3nM for MVD | |||
| 20631047 | 2010 | Xenin | 25 | Free | Free | Linear | L | None | Secreted from intestinal K-cells | Regulates insulin | 360 minutes | Not mentioned | 162 ±6 | Mice plasma proteases | HPLC | Mice plasma | in vitro | 1429581 | None | Stimulated insulin secretion at 5.6 mM In clonal BRIN-BD11 cells | |||
| 17292977 | 2007 | AC3174 | 39 | Free | Amidation | Linear | L | None | Analog of exendin-4 | Regulates blood glucose | 5 hours | Not mentioned | >5 | Human plasma proteases | LC/MS | Human plasma | in vitro | None | None | IC50=0.66 ±0.13nM for binding to GLP-1 receptor | |||
| 17292977 | 2007 | AC3174 | 39 | Free | Amidation | Linear | L | None | Analog of exendin-4 | Regulates blood glucose | Not mentioned | Not mentioned | 42 ±3.4 | Rat plasma proteases | ELISA | Subcutaneously administion of 10 µg/kg dose to Sprague Dawley rats | in vivo | None | None | ED50=1.2 µg/kg for glucose lowering in db/db mice | |||
| 17292977 | 2007 | AC3174 | 39 | Free | Amidation | Linear | L | None | Analog of exendin-4 | Regulates blood glucose | Not mentioned | Not mentioned | 43 ±4.0 | Rat plasma proteases | ELISA | Subcutaneously administion of 100 µg/kg dose to Sprague Dawley rats | in vivo | None | None | ED50=1.3 µg/kg for glucose lowering in C57BL/6 mice | |||
| 17107718 | 2006 | Glucagon-like peptide-2 (GLP-2) | 33 | Free | Free | Linear | L | None | Posttranslational processing of proglucagon | Stimulate intestinal growth | Not mentioned | Not mentioned | 6.8 ±0.8 | Pig plasma proteases | ELISA | Infused into blood of pigs | in vivo | None | None | Not reported | |||
| 17107718 | 2006 | Glucagon-like peptide-2 (GLP-2) | 33 | Free | Free | Linear | L | None | Posttranslational processing of proglucagon | Stimulate intestinal growth | Not mentioned | Not mentioned | 9.9 ±0.8 | Pig plasma proteases with valine-pyrrolidide (DPP-IV inhibitor) | ELISA | Infused into blood of pigs | in vivo | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 1 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 2.7013 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 2 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0629 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 3 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0556 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 4 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0103 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 5 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0088 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 6 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0122 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 7 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0101 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 8 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0094 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 9 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1969 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 10 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.2897 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 11 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0485 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 12 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1557 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 13 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.089 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 14 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0469 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 15 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.2911 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 16 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1596 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 17 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0512 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 18 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0132 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 19 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0077 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 20 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0111 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 21 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0135 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 22 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0122 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 23 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0092 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 24 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.021 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 25 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0027 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 26 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0094 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 27 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0069 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 28 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0119 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 29 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1526 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 30 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 25.2445 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 31 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 40.1296 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 32 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 17.8114 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 33 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 7.122 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 34 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 13.4815 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 35 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 6.4814 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 36 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 4.3435 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 37 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.1378 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 38 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1177 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 39 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0148 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 40 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0527 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 41 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1504 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 42 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0939 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 43 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 4.1593 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 44 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 20.6999 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 45 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.2963 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 46 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.012 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 47 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0026 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 48 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0037 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 49 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0019 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 50 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0035 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 51 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0031 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 52 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0052 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 53 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1052 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 54 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 11.4998 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 55 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.466 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 56 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1016 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 57 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.3817 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 58 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1101 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 59 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0263 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 60 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0128 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 61 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0225 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 62 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0244 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 63 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0238 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 64 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0336 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 65 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0242 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 66 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0812 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 67 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1293 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 68 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0514 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 69 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0325 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 70 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0224 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 71 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0156 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 72 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.2344 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 73 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 3.3348 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 74 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.7564 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 75 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.3309 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 76 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0066 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 77 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0072 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 78 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0038 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 79 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0049 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 80 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.3384 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 81 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1866 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 82 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 4.5647 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 83 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.2013 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 84 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0195 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 85 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0264 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 86 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0165 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 87 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0087 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 88 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0051 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 89 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0054 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 90 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0039 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 91 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0053 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 92 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0131 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 93 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0329 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 94 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 7.6573 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 95 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.6468 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 96 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0033 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 97 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0047 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 98 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0063 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 99 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.131 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 100 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 2.1948 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 101 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 19.4782 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 102 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 3.8079 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 103 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.124 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 104 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.088 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 105 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.006 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 106 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0025 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 107 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0015 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 108 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.006 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 109 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0082 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 110 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1745 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 111 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0072 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 112 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0103 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 113 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0135 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 114 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0183 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 115 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0767 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 116 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0648 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 117 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 3.844 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 118 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1692 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 119 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0949 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 120 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0317 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 121 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.323 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 122 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 8.3587 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 123 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.3722 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 124 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1719 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 125 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.0014 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 126 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.5162 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 127 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0686 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 128 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0663 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 129 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0667 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 130 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0541 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 131 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0563 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 132 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.4176 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 133 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.5842 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 134 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.9286 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 135 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0399 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 136 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0072 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 137 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0037 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 138 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0008 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 139 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0017 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 140 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0044 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 141 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0088 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 142 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0056 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 143 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0367 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 144 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0093 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 145 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0124 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 146 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0294 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 147 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0787 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 148 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1194 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 149 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.8333 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 150 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0154 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 151 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0178 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 152 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.019 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 153 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1849 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 154 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.7012 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 155 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.6149 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 156 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.5216 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 157 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.5455 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 158 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0401 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 159 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0451 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 160 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0465 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 161 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0192 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 162 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1691 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 163 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1777 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 164 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1356 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 165 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.7772 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 166 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1388 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 167 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1025 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 168 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1284 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 169 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0967 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 170 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.7169 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 171 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 4.0618 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 172 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 3.1271 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 173 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0711 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 174 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0548 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 175 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0426 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 176 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0246 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 177 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0788 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 178 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0759 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 179 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0569 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 180 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0056 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 181 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0042 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 182 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0046 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 183 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0185 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 184 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0929 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 185 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0719 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 186 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0048 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 187 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0015 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 188 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0012 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 189 | 10 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0014 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 190 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0097 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 191 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0084 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 192 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0068 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 193 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0084 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 194 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0098 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 195 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0103 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 196 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0201 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 197 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0074 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 198 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0851 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 199 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0892 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 200 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0575 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 201 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0425 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 202 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0327 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 203 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0167 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 204 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0125 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 205 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0077 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 206 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0088 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 207 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0063 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 208 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0045 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 209 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0037 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 210 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.004 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 211 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0033 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 212 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0038 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 213 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0044 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 214 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0045 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 215 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0085 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 216 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0111 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 217 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0131 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 218 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1209 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 219 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 5.693 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 220 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 6.4211 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 221 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 5.0348 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 222 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 1.3951 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 223 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.4688 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 224 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.193 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 225 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0267 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 226 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0499 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 227 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1029 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 228 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0614 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 229 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1104 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 230 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1963 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 231 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0514 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 232 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0223 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 233 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0054 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 234 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0025 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 235 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0011 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 236 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0014 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 237 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0011 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 238 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0032 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 239 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0031 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 240 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0023 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 241 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0028 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 242 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0281 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 243 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.2682 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 244 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1018 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 245 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0298 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 246 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0143 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 247 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0152 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 248 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0093 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 249 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0085 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 250 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0052 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 251 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0085 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 252 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.011 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 253 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0207 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 254 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0155 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 255 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0183 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 256 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0247 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 257 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0297 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 258 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0322 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 259 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0223 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 260 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0078 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 261 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1455 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 262 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0095 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 263 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0099 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 264 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0085 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 265 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0032 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 266 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0033 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 267 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.005 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 268 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0069 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 269 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1618 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 270 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0332 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 271 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0371 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 272 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0236 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 273 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.008 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 274 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0051 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 275 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0061 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 276 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.003 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 277 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0028 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 278 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0037 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 279 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0057 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 280 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0084 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 281 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0101 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 282 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0037 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 283 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0047 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 284 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0049 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 285 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0041 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 286 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0076 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 287 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.005 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 288 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1097 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 289 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1086 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 290 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0696 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 291 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0055 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 292 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.002 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 293 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0022 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 294 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0021 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 295 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0025 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 296 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0021 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 297 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0047 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 298 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0026 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 299 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0075 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 300 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0073 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 301 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0034 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 302 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0134 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 303 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.022 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 304 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0507 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 305 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.041 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 306 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0444 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 307 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0325 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 308 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0306 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 309 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0139 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 310 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1049 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 311 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.2344 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 312 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1597 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 313 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0265 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 314 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0393 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 315 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0228 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 316 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0345 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 317 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0424 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 318 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0653 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 319 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0497 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 320 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0286 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 321 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0414 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 322 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0139 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 323 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.006 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 324 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0021 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 325 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0021 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 326 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0014 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 327 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0012 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 328 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0016 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 329 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.003 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 330 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0054 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 331 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0051 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 332 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0321 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 333 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0225 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 334 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0211 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 335 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0298 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 336 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.017 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 337 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0276 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 338 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0241 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 339 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0262 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 340 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.024 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 341 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0361 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 342 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.2471 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 343 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.3682 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 344 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0601 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 345 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0601 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 346 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0526 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 347 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0502 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 348 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0475 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 349 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0463 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 350 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0154 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 351 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1789 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 352 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0901 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 353 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0783 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 354 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1269 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 355 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1531 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 356 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.195 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 357 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1676 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 358 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.1212 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 359 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0694 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 360 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0475 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 361 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0261 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 362 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0214 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 363 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0322 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 364 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0389 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 365 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0233 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 366 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0029 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 367 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0038 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 368 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0031 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 369 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0038 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 370 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0046 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 371 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0055 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 372 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0038 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 373 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0025 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 374 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0008 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 19159331 | 2009 | Peptide 375 | 16 | 2,4-dichlorophenoxyacetic acid with (CH2)n-spacers | Biotinylation with PEG spacer | Linear | L | None | Synthetic | Not mentioned | 120 minutes | 67 pico molar | 0.0009 | Murine crude intestinal proteases | Proteolysis assay | Murine crude intestinal protease preparetion | in vitro | None | None | Not reported | |||
| 17904340 | 2008 | GLP-1 | 30 | Free | Amidation | Linear | L | None | GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 0.51 ±0.02 | Proteases in rat intestinal fluid | RP-HPLC | Rat intestinal fluid | in vitro | None | None | Oral hypoglycemic efficacy in db/db mice was 2.7 ±12.1% | |||
| 17904340 | 2008 | GLP-1 | 30 | Free | Amidation | Linear | L | None | GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 0.79 ±0.01 | Proteases in rat intestinal homogenate | RP-HPLC | Rat intestinal homogenate | in vitro | None | None | Oral hypoglycemic efficacy in db/db mice was 2.7 ±12.1% | |||
| 17904340 | 2008 | Lys34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 1.17 ±0.08 | Proteases in rat intestinal fluid | RP-HPLC | Rat intestinal fluid | in vitro | None | None | Intraperitoneal hypoglycemic efficacy in db/db mice was 30 ±7.2% | |||
| 17904340 | 2008 | Lys34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 1.34 ±0.07 | Proteases in rat intestinal homogenate | RP-HPLC | Rat intestinal homogenate | in vitro | None | None | Intraperitoneal hypoglycemic efficacy in db/db mice was 30 ±7.2% | |||
| 17904340 | 2008 | Lys26,34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th and 26th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 4.34 ±0.21 | Proteases in rat intestinal fluid | RP-HPLC | Rat intestinal fluid | in vitro | None | None | Oral hypoglycemic efficacy in db/db mice was 25.3 ±6.6% | |||
| 17904340 | 2008 | Lys26,34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th and 26th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 2.77 ±0.05 | Proteases in rat intestinal homogenate | RP-HPLC | Rat intestinal homogenate | in vitro | None | None | Oral hypoglycemic efficacy in db/db mice was 25.3 ±6.6% | |||
| 17904340 | 2008 | GLP-1 | 30 | Free | Amidation | Linear | L | None | GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 0.51 ±0.02 | Proteases in rat intestinal fluid | RP-HPLC | Rat intestinal fluid | in vitro | None | None | EC50=3.64 ±0.25nM insulinotropic activity | |||
| 17904340 | 2008 | GLP-1 | 30 | Free | Amidation | Linear | L | None | GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 0.79 ±0.01 | Proteases in rat intestinal homogenate | RP-HPLC | Rat intestinal homogenate | in vitro | None | None | EC50=3.64 ±0.25nM insulinotropic activity | |||
| 17904340 | 2008 | Lys34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 1.17 ±0.08 | Proteases in rat intestinal fluid | RP-HPLC | Rat intestinal fluid | in vitro | None | None | EC50=3.82 ±0.32nM insulinotropic activity | |||
| 17904340 | 2008 | Lys34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 1.34 ±0.07 | Proteases in rat intestinal homogenate | RP-HPLC | Rat intestinal homogenate | in vitro | None | None | EC50=3.82 ±0.32nM insulinotropic activity | |||
| 17904340 | 2008 | Lys26,34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th and 26th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 4.34 ±0.21 | Proteases in rat intestinal fluid | RP-HPLC | Rat intestinal fluid | in vitro | None | None | EC50=3.85 ±0.21nM insulinotropic activity | |||
| 17904340 | 2008 | Lys26,34-biotin-GLP-1 | 30 | Free | Amidation | Linear | L | Biotinylation at Lys at 34th and 26th position | Biotinylated derivative of GLP-1 | Regulates blood glucose levels | Not reported | 200 µg/ml | 2.77 ±0.05 | Proteases in rat intestinal homogenate | RP-HPLC | Rat intestinal homogenate | in vitro | None | None | EC50=3.85 ±0.21nM insulinotropic activity | |||
| 20585128 | 2010 | Sub3 | 12 | Free | Amidation | Linear | L | None | Derived from bovine peptide bactenecin | Antimicrobial | Not reported | 150 µg/ml | ~60 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=1 µg/ml for S. Aureus | |||
| 20585128 | 2010 | Sub3-Agp | 12 | Free | Amidation | Linear | L | Agp=αamino-3-guanidino-propionic acid | Derivative of Sub3 | Antimicrobial | Not reported | 150 µg/ml | >480 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=1 µg/ml for S. Aureus | |||
| 20585128 | 2010 | Sub3-D | 14 | Free | Amidation | Linear | Mix | None | Derivative of Sub4 | Antimicrobial | Not reported | 150 µg/ml | ~60 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=1 µg/ml for S. Aureus | |||
| 20585128 | 2010 | Sub3-DAgp | 14 | Free | Amidation | Linear | Mix | Agp=αamino-3-guanidino-propionic acid | Derivative of Sub5 | Antimicrobial | Not reported | 150 µg/ml | >480 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=1 µg/ml for S. Aureus | |||
| 20585128 | 2010 | Sub3 | 12 | Free | Amidation | Linear | L | None | Derived from bovine peptide bactenecin | Antimicrobial | Not reported | 150 µg/ml | ~60 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=2 µg/ml for P. Aeruginosa | |||
| 20585128 | 2010 | Sub3-Agp | 12 | Free | Amidation | Linear | L | Agp=αamino-3-guanidino-propionic acid | Derivative of Sub3 | Antimicrobial | Not reported | 150 µg/ml | >480 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=2 µg/ml for P. Aeruginosa | |||
| 20585128 | 2010 | Sub3-D | 14 | Free | Amidation | Linear | Mix | None | Derivative of Sub4 | Antimicrobial | Not reported | 150 µg/ml | ~60 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=2 µg/ml for P. Aeruginosa | |||
| 20585128 | 2010 | Sub3-DAgp | 14 | Free | Amidation | Linear | Mix | Agp=αamino-3-guanidino-propionic acid | Derivative of Sub5 | Antimicrobial | Not reported | 150 µg/ml | >480 | Proteases in mouse serum | RP-HPLC | 25% aqueous mouse serum | in vitro | None | None | MIC=2 µg/ml for P. Aeruginosa | |||
| 16472750 | 2006 | E2-PEST | 29 | Free | Free | Linear | L | None | E2 protein from papillomavirus | Gene transcription | Not reported | Not mentioned | 63 | in aCSF | Pulse chase experiment | pMEP-E2 CV-1 cell lines | in vitro | 15014086 | None | Not mentioned | |||
| 16472750 | 2006 | E2-PESTP299A | 29 | Free | Free | Linear | L | None | E2 protein from papillomavirus | Gene transcription | Not reported | Not mentioned | 94 | Not mentioned | Pulse chase experiment | pMEP-E2 CV-1 cell lines | in vitro | 15014086 | None | Not mentioned | |||
| 16472750 | 2006 | E2-PESTE304Q | 29 | Free | Free | Linear | L | None | E2 protein from papillomavirus | Gene transcription | Not reported | Not mentioned | 24 | Not mentioned | Pulse chase experiment | pMEP-E2 CV-1 cell lines | in vitro | 15014086 | None | Not mentioned | |||
| 16586064 | 2006 | GLP1 | 30 | Free | Amidation | Linear | L | None | Synthetically synthesized Glucagon-like peptide-1 | Insulinotropic | Not reported | Not mentioned | 114 ±28 | Rat plasma proteases | RP-HPLC | Rat plasma | in vitro | 16505481 | None | 380 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | GLP1 | 30 | Free | Amidation | Linear | L | None | Synthetically synthesized Glucagon-like peptide-1 | Insulinotropic | Not reported | Not mentioned | 6 ±0.5 | Rat liver proteases | RP-HPLC | Rat liver homogenate | in vitro | 16505481 | None | 380 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | GLP1 | 30 | Free | Amidation | Linear | L | None | Synthetically synthesized Glucagon-like peptide-1 | Insulinotropic | Not reported | Not mentioned | 1 ±0.2 | Rat kidney proteases | RP-HPLC | Rat kidney homogenate | in vitro | 16505481 | None | 380 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | N-PEG/GLP-1 | 30 | Free | Amidation | Linear | L | Pegylation at N terminus His7 | Synthetically synthesized Glucagon-like peptide-1 analogues | Insulinotropic | Not reported | Not mentioned | 7560 ±5635 | Rat plasma proteases | RP-HPLC | Rat plasma | in vitro | 16505481 | None | 290 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | N-PEG/GLP-1 | 30 | Free | Amidation | Linear | L | Pegylation at N terminus His7 | Synthetically synthesized Glucagon-like peptide-1 analogues | Insulinotropic | Not reported | Not mentioned | 250 ±117 | Rat liver proteases | RP-HPLC | Rat liver homogenate | in vitro | 16505481 | None | 290 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | N-PEG/GLP-1 | 30 | Free | Amidation | Linear | L | Pegylation at N terminus His7 | Synthetically synthesized Glucagon-like peptide-1 analogues | Insulinotropic | Not reported | Not mentioned | 23 ±7 | Rat kidney proteases | RP-HPLC | Rat kidney homogenate | in vitro | 16505481 | None | 290 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | Lys-PEG/GLP-1 | 30 | Free | Amidation | Linear | L | Pegylation on Lys34 | Synthetically synthesized Glucagon-like peptide-1 analogues | Insulinotropic | Not reported | Not mentioned | 4471 ±1822 | Rat plasma proteases | RP-HPLC | Rat plasma | in vitro | 16505481 | None | 150 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | Lys-PEG/GLP-1 | 30 | Free | Amidation | Linear | L | Pegylation on Lys34 | Synthetically synthesized Glucagon-like peptide-1 analogues | Insulinotropic | Not reported | Not mentioned | 62 ±23 | Rat liver proteases | RP-HPLC | Rat liver homogenate | in vitro | 16505481 | None | 150 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16586064 | 2006 | Lys-PEG/GLP-1 | 30 | Free | Amidation | Linear | L | Pegylation on Lys34 | Synthetically synthesized Glucagon-like peptide-1 analogues | Insulinotropic | Not reported | Not mentioned | 28 ±1 | Rat kidney proteases | RP-HPLC | Rat kidney homogenate | in vitro | 16505481 | None | 150 ([pmol/l] islet-1 h-1) insulin release at -7 (log [mol/l]) | |||
| 16892368 | 2006 | C46 | 13 | Glycosylation | Amidation | Linear | L | None | Derived from T20 | HIV-1 fusion inhibitory peptide | Not reported | 40 ng peptide/200 mL plasma | 4.75 | Mouse plasma proteases | ELISA | Mouse plasma | in vitro | None | None | IC50=90nM | |||
| 16892368 | 2006 | C46 | 13 | Glycosylation | Amidation | Linear | L | None | Derived from T20 | HIV-1 fusion inhibitory peptide | Not reported | 41 ng peptide/200 mL plasma | 2 | Rat plasma proteases | ELISA | Rat plasma | in vitro | None | None | IC50=90nM | |||
| 16892368 | 2006 | C46 | 13 | Glycosylation | Amidation | Linear | L | None | Derived from T20 | HIV-1 fusion inhibitory peptide | Not reported | 40 ng peptide/200 mL buffer | 0.75 | Not mentioned | ELISA | PBS/1% BSA | in vitro | None | None | IC50=90nM | |||
| 16892368 | 2006 | Dimeric C46 | 26 | Glycosylation | Amidation | Linear | L | None | Derived from T20 | HIV-1 fusion inhibitory peptide | Not reported | 40 ng peptide/200 mL plasma | 1.75 | Mouse plasma proteases | ELISA | Mouse plasma | in vitro | None | None | Not given | |||
| 16892368 | 2006 | Dimeric C46 | 26 | Glycosylation | Amidation | Linear | L | None | Derived from T20 | HIV-1 fusion inhibitory peptide | Not reported | 40 ng peptide/200 mL plasma | 1 | Rat plasma proteases | ELISA | Rat plasma | in vitro | None | None | Not given | |||
| 16892368 | 2006 | Dimeric C46 | 26 | Glycosylation | Amidation | Linear | L | None | Derived from T20 | HIV-1 fusion inhibitory peptide | Not reported | 40 ng peptide/200 mL buffer | 4.25 | Not mentioned | ELISA | PBS/1% BSA | in vitro | None | None | Not given | |||
| 16990557 | 2006 | cNGR | 8 | Acetylation | Amidation | Cyclic | L | None | Synthetic peptide | Targets CD13/APN which is present on angiogenic vessels so used for molecular imaging | Not reported | 0.75μg/g | 9.1 ±0.3 | Proteases present in the tissue of angiogenetic vessels in mouse | Fluorometery | Mouse tissue of myocardial infarction (MI) model | in vivo | None | None | Not given | |||
| 16990557 | 2006 | cNGR | 8 | Acetylation | Amidation | Cyclic | L | None | Synthetic peptide | Targets CD13/APN which is present on angiogenic vessels so used for molecular imaging | Not reported | 0.75μg/g | 15.4 ±3.4 | Mouse plasma proteases | Fluorometery | Mouse plasma of Murine myocardial infarction (MI) model | in vivo | None | None | Not given | |||
| 17266646 | 2007 | Exendin-4 | 39 | Free | Free | Linear | L | None | Salivary secretions of the lizard Heloderma suspectum | Exhibits potent anti-diabetic or glucoregulatory activities | Not reported | 100μg/ml | 9.57 | Not mentioned | RP-HPLC and MS-TOF | Human blood plasma | in vitro | None | None | Not given | |||
| 17374660 | 2007 | IPP | 3 | Free | Free | Linear | L | None | Lactotripeptide | ACE(Angeotensin converting enzyme)-inhibiting peptide | Not reported | Not mentioned | ~ 30 | Pancreatic proteases | RP-HPLC | Human blood plasma (oral) | in vivo | None | None | Not given | |||
| 17479256 | 2007 | ANP | 26 | Free | Free | Linear | L | None | Synthetic peptide | Atrial natriuratic peptide | Not reported | 0.05 μg/kg per minute | 2.4 ±0.7 | Human blood proteases | Radioimmunoassay | Human blood plasma | in vitro | None | None | Not given | |||
| 17479256 | 2007 | BNP | 32 | Free | Free | Linear | L | None | Synthetic peptide | Vasodilator | Not reported | 0.01 μg/kg per minute | 12.1 ±3.0 | Human blood proteases | Radioimmunoassay | Human blood plasma | in vitro | None | None | Not given | |||
| 17537541 | 2007 | Vasoactive intestinal peptide (VIP) | 28 | Free | Free | Linear | L | None | Vasoactive intestinal peptide | Neurotransmitter | Not reported | Ki=2.63 ±0.87 nM | 1.38 | Not mentioned | Not mentioned | Rat lung alveolar L2 cells | in vitro | None | None | Not given | |||
| 17537541 | 2007 | IK312532 | 31 | Free | Free | Linear | L | None | Synthetic peptide | VIP analogue | Not reported | Ki=1.36 ±0.29 nM | 4.73 | Not mentioned | Not mentioned | Rat lung alveolar L2 cells | in vitro | None | None | Not given | |||
| 17640899 | 2007 | ENF (T-20) | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.006 µg/ml against IIIB virus virus | |||
| 17640899 | 2007 | ENF (T-20) | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.050 µg/ml against 098 virus virus | |||
| 17640899 | 2007 | ENF (T-20) | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.526 µg/ml against 098-T20 virus virus | |||
| 17640899 | 2007 | ENF (T-20) | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=54.958 µg/ml against 098-T1249 virus virus | |||
| 17640899 | 2007 | ENF (T-20) | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=47.822 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-1249 | 39 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.003 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-1249 | 39 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.013 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-1249 | 39 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.022 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-1249 | 39 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.363 µg/ml against 098-T1249 virus virus | |||
| 17640899 | 2007 | T-1249 | 39 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=8.140 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-651 | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 0.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.008 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-651 | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 0.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.033 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-651 | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 0.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.060 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-651 | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 0.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.151 µg/ml against 098-T1249 virus virus | |||
| 17640899 | 2007 | T-651 | 36 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 0.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=7.599 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-2410 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.008 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-2410 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.032 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-2410 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.039 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-2410 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.137 µg/ml against 098-T1249 virus virus | |||
| 17640899 | 2007 | T-2410 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=4.975 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-290676 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.006 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-290676 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.013 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-290676 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.022 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-290676 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.072 µg/ml against 098-T1249 virus virus | |||
| 17640899 | 2007 | T-290676 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 1.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=1.314 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-2635 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 16.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.007 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-2635 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 16.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.018 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-2635 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 16.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.025 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-2635 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 16.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.015 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-2635 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 16.3 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.021 µg/ml against 098-T651 virus virus | |||
| 17640899 | 2007 | T-2544 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.1 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.007 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-2544 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.1 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.026 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-2544 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.1 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.033 µg/ml against 098-T20 virus virus | |||
| 17640899 | 2007 | T-2544 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.1 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.014 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-2544 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 5.1 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.021 µg/ml against 098-T651 virus virus | |||
| 17640899 | 2007 | T-267209 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 3.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.007 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-267209 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 3.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.021 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-267209 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 3.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.034 µg/ml against 098-T20 virus virus | |||
| 17640899 | 2007 | T-267209 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 3.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.024 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-267209 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 3.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.039 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-267221 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 15.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.011 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-267221 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 15.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.035 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-267221 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 15.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.028 µg/ml against 098-T20 virus virus | |||
| 17640899 | 2007 | T-267221 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 15.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.035 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-267221 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 15.2 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.050 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-267226 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 7.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.007 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-267226 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 7.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.021 µg/ml against 098 | |||
| 17640899 | 2007 | T-267226 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 7.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.035 µg/ml against 098-T20 virus virus | |||
| 17640899 | 2007 | T-267226 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 7.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.030 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-267226 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 7.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.020 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-267225 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 12.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.019 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-267225 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 12.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.043 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-267225 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 12.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.079 µg/ml against 098-T20 virus virus | |||
| 17640899 | 2007 | T-267225 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 12.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.038 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-267225 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 12.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.196 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-267227 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 17.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.012 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-267227 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 17.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.045 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-267227 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 17.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.028 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-267227 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 17.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.025 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-267227 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 17.9 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.044 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-291022 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 28.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.022 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-291022 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 28.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.049 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-291022 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 28.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.093 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-291022 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 28.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.046 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-291022 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 28.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.242 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-290822 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.030 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-290822 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.054 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-290822 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.084 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-290822 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.147 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-290822 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 8.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.242 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-290821 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 9.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.065 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-290821 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 9.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.118 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-290821 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 9.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.154 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-290821 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 9.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.192 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-290821 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 9.6 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50>20 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-267228 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 30.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.172 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-267228 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 30.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.600 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-267228 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 30.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.416 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-267228 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 30.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.555 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-267228 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 30.8 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=0.987 µg/ml against 098-T651 virus | |||
| 17640899 | 2007 | T-267229 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 35.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50=3.162 µg/ml against IIIB virus | |||
| 17640899 | 2007 | T-267229 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 35.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50>20 µg/ml against 098 virus | |||
| 17640899 | 2007 | T-267229 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 35.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50>20 µg/ml against 098-T20 virus | |||
| 17640899 | 2007 | T-267229 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 35.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50>20 µg/ml against 098-T1249 virus | |||
| 17640899 | 2007 | T-267229 | 38 | Free | Free | Linear | L | None | Synthetic peptide | Antiviral peptide | Not reported | ~1 €“2mg/kg | 35.4 | Monkey blood proteases | RP-HPLC and ESI-MS | Male cynomolgus monkey blood plasma (Intravenous) | in vivo | None | None | IC50>20 µg/ml against 098-T651 virus | |||
| 17986790 | 2007 | GLP-1/HAS | 30 | Free | Human serum albumin | Linear | L | None | Glucagon | Glucose-dependent insulinotropic effect | Not reported | 0.1 µmol/kg | 10 | Mouse blood proteases | ELISA | Mouse plasma (Intraperitoneally administered) | in vivo | None | None | 0.1 mmol/kg had glucose-lowering effect up to 4 h after administration | |||
| 17994612 | 2007 | Exendin-4 (Ex-4) | 39 | Free | Free | Linear | L | None | Salivary gland of the lizard Heloderma suspectum | Glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows down gastric emptying | Not reported | 4.0 mg/kg | 56.7 | Not mentioned | Radioimmunoassay | Monkey (Intravenous injection) | in vivo | None | None | Not given | |||
| 17994612 | 2007 | Exendin-4 (Ex-4) | 39 | Free | Free | Linear | L | None | Salivary gland of the lizard Heloderma suspectum | Glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows down gastric emptying | Not reported | 4.0 mg/kg | 77.4 | Not mentioned | Radioimmunoassay | Monkey (Subcutaneous injection) | in vivo | None | None | CL/F =2.0 ml/h/kg | |||
| 18085721 | 2007 | GLP-1 | 30 | Free | Free | Linear | L | None | Glucagon | Counter-regulatory hormone | Not reported | Not mentioned | ~2 | DPP-IV | ELISA | Mouse plasma | in vivo | None | None | Not given | |||
| 18307313 | 2007 | CAP 1 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 83 µM for S.aureus | |||
| 18307313 | 2007 | CAP 1 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 50 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 1 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 25 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 2 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 2 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 11 µM for S.aureus | |||
| 18307313 | 2007 | CAP 2 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 2 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 11 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 2 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 2 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 3 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 3 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 10 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 10 µM for S.aureus | |||
| 18307313 | 2007 | CAP 3 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 10 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 3 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 10 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 4 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 47 µM for S.aureus | |||
| 18307313 | 2007 | CAP 4 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 6 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 4 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 11 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 5 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 11 µM for S.aureus | |||
| 18307313 | 2007 | CAP 5 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 9 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 5 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 6 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 6 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 14 µM for S.aureus | |||
| 18307313 | 2007 | CAP 6 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 9 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 6 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 1 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 6 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 7 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 11 µM for S.aureus | |||
| 18307313 | 2007 | CAP 7 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 7 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 8 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 3 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 6 µM for S.aureus | |||
| 18307313 | 2007 | CAP 8 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 3 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 8 | 2 | Free | NHBn | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 3 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 3 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 9 | 2 | Free | Y= structure given in paper | Linear | L | BIP | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 35 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for S.aureus | |||
| 18307313 | 2007 | CAP 9 | 2 | Free | Y= structure given in paper | Linear | L | BIP | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 35 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 9 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 35 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 6 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 10 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 9 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 9 µM for S.aureus | |||
| 18307313 | 2007 | CAP 10 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 9 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 10 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 9 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 6 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 11 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 2 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for S.aureus | |||
| 18307313 | 2007 | CAP 11 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 2 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 7 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 11 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 2 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 12 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 8 µM for S.aureus | |||
| 18307313 | 2007 | CAP 12 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 8 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 12 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 5 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 13 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 12 µM for S.aureus | |||
| 18307313 | 2007 | CAP 13 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 12 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 13 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 8 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 14 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 10 µM for S.aureus | |||
| 18307313 | 2007 | CAP 14 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 9 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 14 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 6 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 15 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 8 µM for S.aureus | |||
| 18307313 | 2007 | CAP 15 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 5 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 15 | 2 | Free | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 16 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 145 µM for S.aureus | |||
| 18307313 | 2007 | CAP 16 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 95 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 16 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 81 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 16 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 145 µM for S.aureus | |||
| 18307313 | 2007 | CAP 16 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 95 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 16 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 7 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 81 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 17 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 5 µM for S.aureus | |||
| 18307313 | 2007 | CAP 17 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 17 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 17 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 5 µM for S.aureus | |||
| 18307313 | 2007 | CAP 17 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 17 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | Stable | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 18 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for S.aureus | |||
| 18307313 | 2007 | CAP 18 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC<3 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 18 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC<3 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 18 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for S.aureus | |||
| 18307313 | 2007 | CAP 18 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC<3 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 18 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 30 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC<3 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 19 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 29 µM for S.aureus | |||
| 18307313 | 2007 | CAP 19 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 29 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 19 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 20 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 19 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 29 µM for S.aureus | |||
| 18307313 | 2007 | CAP 19 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 29 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 19 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 20 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 20 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 50 µM for S.aureus | |||
| 18307313 | 2007 | CAP 20 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 50 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 20 | 2 | Free | CH2CH2Ph | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 10 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 20 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 50 µM for S.aureus | |||
| 18307313 | 2007 | CAP 20 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 50 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 20 | 2 | Acetylation | Y= structure given in paper | Linear | L | Bip | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 0.6 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 10 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 21 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 116 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC>100 µM for S.aureus | |||
| 18307313 | 2007 | CAP 21 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 116 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC>100 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 21 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 116 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC>100 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 22 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 17 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 11 µM for S.aureus | |||
| 18307313 | 2007 | CAP 22 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 17 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 10 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 22 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 17 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 4 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 23 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 67 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 25 µM for S.aureus | |||
| 18307313 | 2007 | CAP 23 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 67 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 25 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 23 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 67 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 5 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 24 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 17 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 25 µM for S.aureus | |||
| 18307313 | 2007 | CAP 24 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 17 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 25 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 24 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 17 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC= 5 µM for Methicillin- resistant S.epidermis | |||
| 18307313 | 2007 | CAP 25 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 88 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC>100 µM for S.aureus | |||
| 18307313 | 2007 | CAP 25 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 88 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC>100 µM for Methicillin- resistant S.aureus | |||
| 18307313 | 2007 | CAP 25 | 2 | Free | Amidation | Linear | L | X= structure given in paper | Synthetic peptide | Antimicrobial | Not reported | 1 mg/mL | 88 | Trypsin | RP-HPLC | Trypsin | in vitro | None | None | MIC>100 µM for Methicillin- resistant S.epidermis | |||
| 18413862 | 2008 | A3-APO (Dimer) | 38 | Chex =Cyclohexane carboxylic acid | Free | Linear | L | Dab =2,4-diamino-butyric acid | Synthetic peptide | Antibacterial | Not reported | 5 mg/kg | 100 | Mouse serum proteases | RP-HPLC | Mouse serum | in vitro | None | None | MIC= 16 mg/mL | |||
| 18413862 | 2008 | A3-APO (Dimer) | 38 | Chex =Cyclohexane carboxylic acid | Free | Linear | L | Dab =2,4-diamino-butyric acid | Synthetic peptide | Antibacterial | Not reported | 5 mg/kg | 230 | Mouse serum proteases | RP-HPLC | Mouse serum | in vitro | None | None | MIC= 16 mg/mL | |||
| 18481852 | 2008 | 3A | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 580 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18481852 | 2008 | 3A' | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 910 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18481852 | 2008 | 3B | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 345 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18481852 | 2008 | 3B' | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 655 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18481852 | 2008 | A.A.B | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 190 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18481852 | 2008 | A.A.B' | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 300 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18481852 | 2008 | A'.A'.B | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 325 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18481852 | 2008 | A'.A'.B' | 117 | Acetylation | Amidation | Linear | L | None | Synthetic Collagen peptide | Structural component of connective tissues | Not reported | Not mentioned | 470 | Not mentioned | HPLC and MALDI-TOF | Not reported | in vitro | None | None | Not available | |||
| 18553094 | 2008 | BNP | 32 | Free | Free | Linear | L | None | Pro-Brain natriuretic peptide | Vasodilator | Not reported | Not mentioned | ~22 | Human blood proteases | ELISA | Human plasma | in vitro | None | None | Not available | |||
| 18553094 | 2008 | NT-proBNP | 76 | Free | Free | Linear | L | None | Pro-Brain natriuretic peptide | Vasodilator | Not reported | Not mentioned | ~120 | Human blood proteases | ELISA | Human plasma | in vitro | None | None | Not available | |||
| 19053766 | 2008 | CGRP(8-37)-NH2 derivative 32 | 30 | Acetylation | Amidation | Linear | L | None | Calcitonin gene-related peptide | Neuropeptide | Not reported | 10 µg/ml | 38 | Monkey plasma proteases | ELISA | Monkey plasma | in vitro | None | None | IC50=3.57 ± 0.04 nM | |||
| 19053766 | 2008 | CGRP(8-37)-NH2 derivative 32 | 30 | Acetylation | Amidation | Linear | L | None | Calcitonin gene-related peptide | Neuropeptide | Not reported | 10 µg/ml | 68 | Human plasma proteases | ELISA | Human plasma | in vitro | None | None | IC50=3.57 ± 0.04 nM | |||
| 19223422 | 2009 | HBP-1 | 13 | Free | Free | Linear | L | None | Synthetic peptide | Not mentioned | Not reported | Not mentioned | 55 | Not mentioned | HPLC | Human serum | in vitro | None | None | IC50=38.9nM | |||
| 19403044 | 2008 | GLP-1/Fc | 30 | Free | Amidation | Linear | L | None | Proglucagon molecule | Antidiabetic | Not reported | 16nM | ~20 | Rabbit serum proteases | Luciferase reporter assay | Rabbit serum | ex vivo | None | None | Not available | |||
| 19403044 | 2008 | GLP-1 | 30 | Free | Amidation | Linear | L | None | Proglucagon molecule | Antidiabetic | Not reported | 0.4nM | <5 | Rabbit serum proteases | Luciferase reporter assay | Rabbit serum | ex vivo | None | None | Not available | |||
| 19413309 | 2009 | HM3 | 17 | Free | Free | Linear | L | None | RGD- modified endostatin derived peptide | Antitumor | Not reported | 1mg/ml | 27.66 ± 7.37 | Rat blood proteases | RP-HPLC | Rat blood serum (Intravenous injection) | in vivo | None | None | Less active in the inhibition of angiogenesis in the chorioallantoic membrane of chick embryos | |||
| 19413309 | 2009 | PEG10k-HM-3 | 17 | Methoxypoly(ethylene glycol)-aldehyde (mPEG-ALD) | Free | Linear | L | None | RGD- modified endostatin derived peptide | Antitumor | Not reported | 1mg/ml | 162.08 ± 36.57 | Rat blood proteases | RP-HPLC | Rat blood serum (Intravenous injection) | in vivo | None | None | More active in the inhibition of angiogenesis in the chorioallantoic membrane of chick embryos | |||
| 19458086 | 2009 | ANP | 28 | Free | Free | Cyclic (C7-C23) | L | None | C terminus of atrial natriuretic peptide | Natriuretic, diuretic and vasorelaxant | Not reported | 1 µM | 2.6 | Human kidney membrane proteases | Radioimmunoassay | Human kidney membranes | in vitro | None | None | IC50=2.4nM | |||
| 19458086 | 2009 | fsANP | 40 | Free | Free | Cyclic (C7-C23) | L | None | C terminus of atrial natriuretic peptide | Natriuretic, diuretic and vasorelaxant | Not reported | 1 µM | 4.5 | Human kidney membrane proteases | Radioimmunoassay | Human kidney membranes | in vitro | None | None | IC50=3.2nM | |||
| 19531053 | 2009 | GLP-1 | 30 | Free | Amidation | Linear | L | None | Proglucagon molecule | Antidiabetic | Not reported | Not mentioned | 20 | DPP IV | ELISA | Mice (Subcutaneous injection) | in vivo | None | None | Not available | |||
| 19572636 | 2009 | N-WASP181-200 | 20 | Free | Free | Linear | L | None | Synthetic peptide | Inhibits renal accumulation of aminoglycoside antibiotics | Not reported | 1 mg/mL | 6.7 | Not mentioned | HPLC | Rat renal brush border membrane suspension | in vitro | None | None | IC50=0.041 mM with gentamicin | |||
| 19572636 | 2009 | PEG1k-N-W | 20 | Pegylation | Free | Linear | L | None | Synthetic peptide | Inhibits renal accumulation of aminoglycoside antibiotics | Not reported | 100 µg/mL | 12.9 | Not mentioned | HPLC | Rat renal brush border membrane suspension | in vitro | None | None | IC50=0.128 mM with gentamicin | |||
| 19572636 | 2009 | N-WASP181-200 | 20 | Free | Free | Linear | L | None | Synthetic peptide | Inhibits renal accumulation of aminoglycoside antibiotics | Not reported | 100 µg/mL | 6.7 | Not mentioned | HPLC | Rat renal brush border membrane suspension | in vitro | None | None | IC50=46.1 mg/kg with Arbekacin | |||
| 19572636 | 2009 | N-WASP181-200 | 20 | Free | Free | Linear | L | None | Synthetic peptide | Inhibits renal accumulation of aminoglycoside antibiotics | Not reported | 100mg/kg | 2.7 | Not mentioned | HPLC | Rat blood plasma (Intravenous) | in vivo | None | None | IC50=46.1 mg/kg with Arbekacin | |||
| 19572636 | 2009 | PEG1k-N-W | 20 | Pegylation | Free | Linear | L | None | Synthetic peptide | Inhibits renal accumulation of aminoglycoside antibiotics | Not reported | 100mg/kg | 4.6 | Not mentioned | HPLC | Rat blood plasma (Intravenous) | in vivo | None | None | IC50=17.8 mg/kg with Arbekacin | |||
| 19572636 | 2009 | PEG1k-N-W | 20 | Pegylation | Free | Linear | L | None | Synthetic peptide | Inhibits renal accumulation of aminoglycoside antibiotics | Not reported | 100 µg/mL | 12.9 | Not mentioned | HPLC | Rat renal brush border membrane suspension | in vitro | None | None | IC50=17.8 mg/kg with Arbekacin | |||
| 19601640 | 2009 | TATp | 11 | Free | Free | Linear | L | None | Synthetic peptide | Cell penetrating peptide | Not reported | 10 µL | >400 | Not mentioned | HPLC | Human plasma | in vitro | None | None | Not available | |||
| 19602537 | 2009 | GLPAG | 37 | Free | Cholesterol moiety | Linear | L | None | Proglucagon molecule | Antidiabetic | Not reported | 3mg/kg | Stable | Mouse blood proteases | RP-HPLC and ESI-MS | Mouse plasma (Subcutaneous injection) | in vivo | None | None | EC 50, cAMP=180nM for mGCGR | |||
| 19602537 | 2009 | DualAG | 37 | Free | Cholesterol moiety | Linear | L | None | Proglucagon molecule | Protease-resistant dual GLP1R/GCGR agonist | Not reported | 3mg/kg | 1.7 | Mouse blood proteases | RP-HPLC and ESI-MS | Mouse plasma (Subcutaneous injection) | in vivo | None | None | EC 50, cAMP=1.5nM for mGCGR | |||
| 19602537 | 2009 | Oxm | 37 | Free | Free | Linear | L | None | Proglucagon molecule | Antidiabetic | Not reported | 3mg/kg | ~8-12 | Mouse blood proteases | RP-HPLC and ESI-MS | Mouse plasma (Subcutaneous injection) | in vivo | None | None | EC 50, cAMP=6.2nM for mGCGR | |||
| 19715558 | 2009 | RIAD | 18 | Free | Free | Linear | L | None | Synthetic peptide | Displaces PKA (protein kinase A) type I from the AKAP (A-kinase-anchoring protein) ezrin | Not reported | Not mentioned | 1.5 | Human serum proteases | HPLC | Human serum | in vitro | None | None | Not available | |||
| 19762245 | 2009 | TY005 | 8 | Free | O-[3 €™,5 €™-(CF3 )2 Bzl] | Linear | Mix | None | Synthetic peptide | Analgesic | Not reported | 50 µg/ml | 24 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | Not available | |||
| 19762245 | 2009 | TY027 | 8 | Free | NH-[3 €™,5 €™-(CF3 )2 Bzl] | Linear | Mix | None | Synthetic peptide dreived from opioid and NK1 pharmacophore | Analgesic | Not reported | 50 µg/ml | 4.8 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | Not available | |||
| 19762245 | 2009 | TY039 | 8 | Free | NH-[3 €™,5 €™-(CF3 )2 Bzl] | Cyclic (C2-C5) | Mix | None | Synthetic peptide | Analgesic | Not reported | 50 µg/ml | >6 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | Not available | |||
| 19762245 | 2009 | TY037 | 8 | Free | NH-[3 €™,5 €™-(CF3 )2 Bzl] | Cyclic (C2-C5) | Mix | None | Synthetic peptide | Analgesic | Not reported | 50 µg/ml | 4.9 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | Not available | |||
| 19762245 | 2009 | TY035 | 8 | Free | NH-[3 €™,5 €™-(CF3 )2 Bzl] | Cyclic (C2-C7) | Mix | Nle | Synthetic peptide | Analgesic | Not reported | 50 µg/ml | >6 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | Not available | |||
| 19762245 | 2009 | TY038 | 8 | Free | NH-[3 €™,5 €™-(CF3 )2 Bzl] | Cyclic (C2-C7) | Mix | Nle | Synthetic peptide | Analgesic | Not reported | 50 µg/ml | >6 | Rat plasma proteases | HPLC | Rat plasma | in vitro | None | None | Not available | |||
| 17292492 | 2007 | NT-ANP | 98 | Free | Free | Linear | L | None | ANP (A- type natriuretic peptide) | Natriuretic, diuretic and vasorelaxant | Not reported | 650fmol/ml | 1 | Human blood proteases | Radioimmunoassay | Human blood | in vitro | None | None | Not mentioned | |||
| 18353507 | 2008 | PACAP38 | 38 | Free | Amidation | Linear | L | None | Synthetically synthesised pituitary adenylate cyclase-activating polypeptide | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | 23 ±6 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 7.7 ±1.4 nM | |||
| 18353507 | 2008 | PACAP38 | 38 | Free | Amidation | Linear | L | None | Synthetically synthesised pituitary adenylate cyclase-activating polypeptide | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | 4.3 ±0.3 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 7.7 ±1.4 nM | |||
| 18353507 | 2008 | Acetyl-PACAP38 | 38 | Acetylation | Amidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 5.6 ±1.5 nM | |||
| 18353507 | 2008 | Hexanoyl-PACAP38 | 38 | Hexanoylation | Amidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 8.3 ±1.8 nM | |||
| 18353507 | 2008 | [Aib2]PACAP38 | 38 | Free | Amidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | 65 ±8 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 7.1 ±1.4 nM | |||
| 18353507 | 2008 | [D-Ser2]PACAP38 | 38 | Free | Amidation | Linear | Mix | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 9.7 ±2.5 nM | |||
| 18353507 | 2008 | [ψCH2-NH21-22]PACAP38 | 38 | Free | Amidation | Linear | L | [ψCH2-NH21-22] | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | 18 ±2 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 59 ±17 nM | |||
| 18353507 | 2008 | [Ala20]PACAP38 | 38 | Free | Amidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | 8.3 ±1.2 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 1.2 ±0.4 nM | |||
| 18353507 | 2008 | [Ala21]PACAP38 | 38 | Free | Amidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | 6.6 ±0.5 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 2.0 ±0.5 nM | |||
| 18353507 | 2008 | Acetyl-PACAP38-propylamide | 38 | Acetylation | Propylamidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 2.9 ±0.9 nM | |||
| 18353507 | 2008 | Acetyl-PACAP38-hexylamide | 38 | Acetylation | Hexylamidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 3.5 ±0.7 nM | |||
| 18353507 | 2008 | Acetyl-[Ala14, Ala20]PACAP38-propylamide | 38 | Acetylation | Propylamidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 5.3 ±1.7 nM | |||
| 18353507 | 2008 | Acetyl-[Ala14, Ala20]PACAP38-propylamide | 38 | Acetylation | Propylamidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | 15 ±2 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 5.3 ±1.7 nM | |||
| 18353507 | 2008 | Acetyl-[Ala15, Ala20]PACAP38-propylamide | 38 | Acetylation | Propylamidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 1.8 ±0.7 nM | |||
| 18353507 | 2008 | Acetyl-[Ala15, Ala20]PACAP38-propylamide | 38 | Acetylation | Propylamidation | Linear | L | None | Synthetic analog of PACAP38 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | 25 ±2 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 1.8 ±0.7 nM | |||
| 18353507 | 2008 | PACAP27 | 27 | Free | Amidation | Linear | L | None | Synthetically synthesised pituitary adenylate cyclase-activating polypeptide | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | 39 ±4 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 9.6 ±2.4 nM | |||
| 18353507 | 2008 | PACAP27 | 27 | Free | Amidation | Linear | L | None | Synthetically synthesised pituitary adenylate cyclase-activating polypeptide | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | >120 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 9.6 ±2.4 nM | |||
| 18353507 | 2008 | Acetyl-PACAP27 | 27 | Acetylation | Amidation | Linear | L | None | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 9.6 ±1.5 nM | |||
| 18353507 | 2008 | Hexanoyl-PACAP27 | 27 | Hexanoylation | Amidation | Linear | L | None | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 10.6 ±2.4 nM | |||
| 18353507 | 2008 | [Aib2]PACAP27 | 27 | Free | Amidation | Linear | L | Aib | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | 145 ±23 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 7.9 ±1.8 nM | |||
| 18353507 | 2008 | [D-Ser2]PACAP27 | 27 | Free | Amidation | Linear | L | None | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 10.3 ±2.1 nM | |||
| 18353507 | 2008 | Acetyl-PACAP27-propylamide | 27 | Acetylation | Propylamidation | Linear | L | None | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 6.7 ±1.2 nM | |||
| 18353507 | 2008 | Acetyl-PACAP27-propylamide | 27 | Acetylation | Propylamidation | Linear | L | None | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | >120 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 6.7 ±1.2 nM | |||
| 18353507 | 2008 | Acetyl-PACAP27-hexylamide | 27 | Acetylation | Hexylamidation | Linear | L | None | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-5 M | >240 | DPP IV | RP-HPLC and MS-MALDI-TOF | DPP IV | in vitro | None | None | IC50 = 5.6 ±1.3 nM | |||
| 18353507 | 2008 | Acetyl-PACAP27-hexylamide | 27 | Acetylation | Hexylamidation | Linear | L | None | Synthetic analog of PACAP27 | Therapeutic Neuropeptide for neurodegenerative diseases. | Not reported | 10-4 M | >120 | Human plasma proteases | RP-HPLC and MS-MALDI-TOF | Human plasma | in vitro | None | None | IC50 = 5.6 ±1.3 nM | |||
| 19041716 | 2009 | SST (Somatostatin) | 14 | Free | Free | Cyclic (C3-C14) | L | None | Somatostatin | Neurotransmitter | Not reported | 1.8 mg/ml | 7.6 | Rat blood proteases | ELISA | Rat plasma (Intravenous injection) | in vivo | None | None | Not available | |||
| 19041716 | 2009 | LCNP/SST (Somatostatin adsorbed on Liquid crystalline nanoparticles for 10 min) | 14 | Free | Free | Cyclic (C3-C14) | L | None | Somatostatin adsorbed on Liquid crystalline nanoparticles | Neurotransmitter | Not reported | 1.8 mg/ml | 0.73 ±0.03 | Rat blood proteases | ELISA | Rat plasma (Intravenous injection) | in vivo | None | None | Not available | |||
| 19041716 | 2009 | LCNP/SST (Somatostatin adsorbed on Liquid crystalline nanoparticles for 18 hours) | 14 | Free | Free | Cyclic (C3-C14) | L | None | Somatostatin adsorbed on Liquid crystalline nanoparticles | Neurotransmitter | Not reported | 1.8 mg/ml | 0.79 ±0.17 | Rat blood proteases | ELISA | Rat plasma (Intravenous injection) | in vivo | None | None | Not available | |||
| 19041716 | 2009 | LCNP/SST (encapsulated within Liquid crystalline nanoparticles) | 14 | Free | Free | Cyclic (C3-C14) | L | None | Somatostatin encapsulated within Liquid crystalline nanoparticles | Neurotransmitter | Not reported | 1.8 mg/ml | 1.23 ±0.16 | Rat blood proteases | ELISA | Rat plasma (Intravenous injection) | in vivo | None | None | Not available | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 55 µg/kg | 2.335 ±1.732 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Men) (Intravenous bolus dose) | in vivo | None | None | Not available | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 55 µg/kg | 2.774 ±1.797 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Women) (Intravenous bolus dose) | in vivo | None | None | Not available | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 110 µg/kg | 2.301 ±0.857 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Men) (Intravenous bolus dose) | in vivo | None | None | Not available | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 110 µg/kg | 2.435 ±0.907 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Women) (Intravenous bolus dose) | in vivo | None | None | Not available | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 220 µg/kg | 2.028 ±0.472 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Men) (Intravenous bolus dose) | in vivo | None | None | Not available | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 220 µg/kg | 2.931 ±0.971 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Women) (Intravenous bolus dose) | in vivo | None | None | Not available | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 180 μg/kg plus 2.0 μg/min €¢kg | 2.824 ±0.219 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Men) (Intravenous bolus followed by a continuous infusion of batifiban injection) | in vivo | None | None | 73.19 ±19.15% inhibition of platelet aggregation | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 180 μg/kg plus 2.0 μg/min €¢kg | 3.032 ±0.383 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Women) (Intravenous bolus followed by a continuous infusion of batifiban injection) | in vivo | None | None | 63.67 ±21.94% inhibition of platelet aggregation | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 220 μg/kg plus 2.5 μg/min €¢kg | 2.983 ±0.770 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Men) (Intravenous bolus followed by a continuous infusion of batifiban injection) | in vivo | None | None | 82.91 ±3.96% inhibition of platelet aggregation | |||
| 19224155 | 2009 | Batifiban | 6 | Free | Free | Cyclic (C1-C6) | L | None | Synthetic peptide | Platelet glycoprotein GP …¡b/ …¢a antagonist | Not reported | 220 μg/kg plus 2.5 μg/min €¢kg | 3.120 ±0.322 | Human blood plasma proteases | HPLC, MS-MS | Human blood plasma (Women) (Intravenous bolus followed by a continuous infusion of batifiban injection) | in vivo | None | None | 88.98 ±11.615 inhibition of platelet aggregation | |||
| 19533722 | 2009 | C6 | 12 | Free | Free | Linear | L | None | Synthetic peptide | Mimic putative inhibitor epitopes (mimotopes), | Not reported | 150 µM | ~12 | Human plasma proteases | ELISA | Human plasma | in vitro | None | None | IC50 =30 €“50 µM | |||
| 19836183 | 2010 | BNP | 32 | Free | Free | Linear | L | None | Porcine brain | Vasodilator | Not reported | 31.2ng/ml | 3.1 | Mouse plasma proteases | ELISA | Mouse plasma | in vivo | None | None | Not mentioned | |||
| 20418955 | 2010 | Glucagon | 29 | Free | Free | Linear | L | None | Pancreas | Plays a major regulatory role in controlling hypoglycemia | Not reported | Not mentioned | <10 | Human blood proteases | ELISA | Human serum | in vitro | None | None | Not available | |||
| 20418955 | 2010 | Gcg-XTEN-288 (glucagon-XTEN fusion peptide) | 29 | Free | XTEN-288 | Linear | L | None | Glucagon-288 amino acid XTEN fusion peptide | Glucose homeostasis | Not reported | 12 nmol/kg | 9 | Monkey blood proteases | ELISA | Monkey plasma (Subcutaneous) | in vivo | None | None | Biologically active in cynomolgus monkeys for 6 hours | |||
| N.A. | 2009 | DX-890 | 56 | Free | Free | Linear | L | None | Kunitz domain peptide | Protease inhibitor | N.A. | Not mentioned | 165 | Rabbit blood proteases | I-125 radiolabelling method | Rabbit plasma (Intravenous) | in vivo | None | EP2090589A1 | Inhibition constt (Ki) 6 ±1 pM | |||
| N.A. | 2009 | Human Serum Albumin-DX-890 | 56 | Human serum albumin | Free | Linear | L | None | Kunitz domain peptide | Protease inhibitor | N.A. | Not mentioned | 3500 | Rabbit blood proteases | I-125 radiolabelling method | Rabbit plasma (Intravenous) | in vivo | None | EP2090589A1 | Inhibition constt (Ki) 7 ±1 pM | |||
| N.A. | 2009 | DX-890 | 56 | Free | Free | Linear | L | None | Kunitz domain peptide | Protease inhibitor | N.A. | Not mentioned | 79.44 | Mouse blood proteases | I-125 radiolabelling method | Mouse plasma (Intravenous) | in vivo | None | EP2090589A1 | Not mentioned | |||
| N.A. | 2009 | DX-890-Human Serum Albumin | 56 | Free | Human serum albumin | Linear | L | None | Kunitz domain peptide | Protease inhibitor | N.A. | Not mentioned | 380 | Mouse blood proteases | I-125 radiolabelling method | Mouse plasma (Intravenous) | in vivo | None | EP2090589A1 | Not mentioned | |||
| N.A. | 2006 | Derivative of Glucagon Like Peptide-2 (GLP-2) | 33 | Free | Amidation | Linear | L | None | GLP-2 | Intestine function modulator | N.A. | 500 nM/ Kg | 1.5 | Rat blood proteases | Radioimmunoassay | Rat plasma (Intravenous) | in vivo | None | US7112567B2 | Increase in wet-weight of small intestine >0.5 g | |||
| N.A. | 2006 | Derivative of Glucagon Like Peptide-2 (GLP-2) | 33 | Free | Amidation | Linear | L | None | GLP-2 | Intestine function modulator | N.A. | 500 nM/ Kg | 0.9 | Not mentioned | Radioimmunoassay | Rat plasma (Subcutaneous) | in vivo | None | US7112567B2 | Not mentioned | |||
| N.A. | 2006 | Derivative of Glucagon Like Peptide-2 (GLP-2) | 34 | Free | Addition of maleimidopropionic acid (MPA) and amidation | Linear | L | None | GLP-2 | Intestine function modulator | N.A. | 500 nM/ Kg | 16.2 | Rat blood proteases | Radioimmunoassay | Rat plasma (Intravenous) | in vivo | None | US7112567B2 | Increase in wet-weight of small intestine ~0.3 g | |||
| N.A. | 2006 | Derivative of Glucagon Like Peptide-2 (GLP-2) | 34 | Free | Addition of maleimidopropionic acid (MPA) and amidation | Linear | L | None | GLP-2 | Intestine function modulator | N.A. | 500 nM/ Kg | 23.8 | Not mentioned | Radioimmunoassay | Rat plasma (Subcutaneous) | in vivo | None | US7112567B2 | Not mentioned | |||
| 15817669 | 2007 | Derivative of Growth hormone releasing factor | 30 | Free | Addition of maleimidopropionic acid (MPA) and amidation | Linear | Mix | None | GRF peptide | Growth harmone and somatostatin releasing factor | N.A. | 1microM/ Kg | 25.8 | Not mentioned | Radioimmunoassay | Rat plasma (Subcutaneous) | in vivo | None | US7268113B2 | Area under curve (AUC) for growth hormone (GH) release >10000 (ng/ml)*minute | |||
| 15817669 | 2007 | Derivative of Growth hormone releasing factor | 30 | Free | Addition of maleimidopropionic acid (MPA) and amidation | Linear | Mix | None | GRF peptide | Growth harmone and somatostatin releasing factor | N.A. | 100 nM/ Kg | 18.7 | Rat blood proteases | Radioimmunoassay | Rat plasma (Intravenous) | in vivo | None | US7268113B2 | Not mentioned | |||
| N.A. | 2009 | Modified Dynorphin (1-13) | 13 | Free | Addition of hydroxyl group | Linear | L | None | Dynorphin peptide | Endogenous opioid found in CNS | N.A. | 4 mg/ ml | 10 | Not mentioned | LC/MS | plasma | in vitro | None | US 20090175821Al | Not mentioned | |||
| N.A. | 2009 | Modified Dynorphin(1-13) | 13 | Free | Amidation | Linear | L | None | Dynorphin peptide | Endogenous opioid found in CNS | N.A. | 4 mg/ ml | 30 | Not mentioned | LC/MS | plasma | in vitro | None | US 20090175821Al | Not mentioned | |||
| N.A. | 2010 | Peptide-B | 8 | Free | Amidation | Linear | Mix | Sar= sarcosine | Glucagon superfamily Peptide A | Insulinotropic peptide | N.A. | 2 mg/ ml | 18.6 | Not mentioned | LC/MS | plasma | in vitro | None | US20110288003 | Not mentioned | |||
| 20503261 | 2010 | GLP-1-PEG | 40 | Free | Addition of NH2-PEG at Cys40 | Linear | L | None | Glucagon like peptide1 | Insulinotropic peptide | N.A. | 0.1 mg/ Kg | 25.8 | Rat blood proteases | Radioimmunoassay | Rat plasma (Intravenous) | in vivo | None | EP1881850B1 | EC50= 0.36 nM | |||
| 20503261 | 2010 | GLP-1-PEG | 40 | Free | Addition of NH2-PEG at Cys40 | Linear | L | None | Glucagon like peptide1 | Insulinotropic peptide | N.A. | 0.1 mg/ Kg | 28.3 | Not mentioned | Radioimmunoassay | Rat plasma (Subcutaneous) | in vivo | None | EP1881850B1 | Not mentioned | |||
| 20503261 | 2010 | GLP-1-PEG | 40 | Free | Addition of NH2-PEG at Cys40 | Linear | L | None | Glucagon like peptide1 | Insulinotropic peptide | N.A. | 0.01 mg/ Kg | 75.69 | Not mentioned | Radioimmunoassay | Monkey plasma (Subcutaneous) | in vivo | None | EP1881850B1 | Not mentioned | |||
| N.A. | 2009 | Human Corticotropic releasing factor (hCRF) | 41 | Free | Free | Linear | L | None | Hypothalamus | Inhibitor of edema and inflammation | N.A. | 100 micro g/ Kg | 62.6 | Not mentioned | ELISA | Rat plasma (Subcutaneous) | in vivo | None | WO2009027844 | Not mentioned | |||
| N.A. | 2009 | Human Corticotropic releasing factor (hCRF) | 41 | Free | Free | Linear | L | None | Hypothalamus | Inhibitor of edema and inflammation | N.A. | 1000 micro g/ Kg | 72.1 | Not mentioned | ELISA | Rat plasma (Subcutaneous) | in vivo | None | WO2009027844 | Not mentioned | |||
| 18937214 | 2009 | Carbofuran (methylcarbamyl-)-labeled tryptic peptide | 29 | Free | Free | Linear | L | Methylcarbamylated at serine (position 8) | Human Bche protein | Pesticide | Not mentioned | Not mentioned | 2 | Human blood proteases | HPLC | Human serum | in vivo | None | None | BChE activity was 88% inhibited at time zero, but became less inhibited with time as carbofuran was released from the active site Ser 198. | |||
| 19165353 | 2009 | NT pro-BNP (N-terminal Pro-Brain natriuretic Peptide) | 76 | Free | Free | Linear | L | None | Brain Natriuretic Peptide | Diuretic,natriuretic and vasodilatory peptide | Not mentioned | Not mentioned | 60-120 | Human plasma proteases | Not mentioned | Human plasma | in vitro | http://www.phoenixpeptide.com/catalog/product_info | None | NT-pro-BNP is an independent predictor of postoperative myocardial injury in patients undergoing vascular surgery | |||
| 19805567 | 2010 | Enfuvirtide | 36 | Acetylation | Free | Linear | L | 19 residue is N15 labelled, also have 13C carbon | Enfuvirtide | Antiretroviral fusion inhibitor | 5, 15, and 30 min and 1, 2, 4, 8, 24, and 48 h after drug injection | dose, 4 mg/kg of body weight | 2.8 | Wistar rats blood protease | LC-MS/MS | Female Wistar rats | in vivo | None | None | Showed an EC50 of about 275 nM | |||
| 19805567 | 2010 | Enfuvirtide-PEG12-CP | 37 | Acetylation | Free | Linear | L | Mal-PEG12-CP was conjugated to Cys-enfuvirtide | Enfuvirtide conjugate | Antiretroviral fusion inhibitor | 5, 15, and 30 min and 1, 2, 4, 8, 24, and 48 h after drug injection | dose, 4 mg/kg of body weight | 10.4 | Wistar rats blood protease | LC-MS/MS | Female Wistar rats | in vivo | None | None | The enfuvirtide-CP conjugates displayed similar EC50s that ranged from 51 nM to 72 nM | |||
| 16302271 | 2006 | Human Glandular Kallikrein 2 (hK2)-activated thapsigargin prodrug | 6 | Acetylation | Free | Linear | L | Ligated with potent cytotoxin thapsigargin, L12ADT | Human glandular kallikrein 2 (hK2) | Antitumor peptide | 24 hours | 6 mg/kg | 40 | Mice blood proteases | Not mentioned | Balb-C mice | in vivo | None | None | Intratumoral concentrations reached levels comparable to the in vitro IC50 of the prodrug with concentrations of 1.25 mM seen at 1 and 4 hr. | |||
| 17065394 | 2006 | Porcine PYY (Peptide YY) | 34 | Free | Amidation | Linear | L | None | Porcine intestine | Neuropeptide | 120 minutes | 25 mg/kg BW per min | 15 | Pigs blood proteases | Double-antibody Radioimmunoassay | Intravenously administred to Crossbred (Large White!Landrace!Duroc) castrated male pigs | in vivo | http://www.genscript.com/peptide/RP10354-Peptide_Y | None | Plasma GH levels significantly increased 30 min after PYY3 €“36 injection compared with the saline-injected group (7.8 ± 2.1 vs 3.0 ± 0.6 ng/ml, P<0.05) | |||
| 17583927 | 2007 | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers (CPP-PMO) | 34 | Free | PMO (5'-ACGTTGAIIIGCATCGTCGC-3') | Linear | L | X = 6-aminohexanoic acid, B = beta-alanine, I = inosine | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Cell penetrating peptide | 24 hours | 15 mg/kg | 0.40 ±0.05 (t1/2 α) | Rat plasma proteases | MALDI-TOF-MS | Intravenous administration in Rat | in vitro | None | None | LD50 of the conjugate administered iv in rats was between 210 and 250 mg/kg | |||
| 17583927 | 2007 | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers (CPP-PMO) | 34 | Free | PMO (5'-ACGTTGAIIIGCATCGTCGC-3') | Linear | L | X = 6-aminohexanoic acid, B = beta-alanine, I = inosine | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Cell penetrating peptide | 24 hours | 30 mg/kg | 0.63 ±0.02 (t1/2 α) | Rat plasma proteases | MALDI-TOF-MS | Intravenous administration in Rat | in vitro | None | None | LD50 of the conjugate administered iv in rats was between 210 and 250 mg/kg | |||
| 17583927 | 2007 | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers (CPP-PMO) | 34 | Free | PMO (5'-ACGTTGAIIIGCATCGTCGC-3') | Linear | L | X = 6-aminohexanoic acid, B = beta-alanine, I = inosine | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Cell penetrating peptide | 24 hours | 150 mg/kg | 1.56 ±0.10 (t1/2 α) | Rat plasma proteases | MALDI-TOF-MS | Intravenous administration in Rat | in vitro | None | None | LD50 of the conjugate administered iv in rats was between 210 and 250 mg/kg | |||
| 17583927 | 2007 | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers (CPP-PMO) | 34 | Free | PMO (5'-ACGTTGAIIIGCATCGTCGC-3') | Linear | L | X = 6-aminohexanoic acid, B = beta-alanine, I = inosine | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Cell penetrating peptide | 24 hours | 15 mg/kg | 5.04 ±0.06 (t1/2 β) | Rat plasma proteases | MALDI-TOF-MS | Intravenous administration in Rat | in vitro | None | None | LD50 of the conjugate administered iv in rats was between 210 and 250 mg/kg | |||
| 17583927 | 2007 | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers (CPP-PMO) | 34 | Free | PMO (5'-ACGTTGAIIIGCATCGTCGC-3') | Linear | L | X = 6-aminohexanoic acid, B = beta-alanine, I = inosine | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Cell penetrating peptide | 24 hours | 30 mg/kg | 5.83 ±0.86 (t1/2 β) | Rat plasma proteases | MALDI-TOF-MS | Intravenous administration in Rat | in vitro | None | None | LD50 of the conjugate administered iv in rats was between 210 and 250 mg/kg | |||
| 17583927 | 2007 | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers (CPP-PMO) | 34 | Free | PMO (5'-ACGTTGAIIIGCATCGTCGC-3') | Linear | L | X = 6-aminohexanoic acid, B = beta-alanine, I = inosine | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Cell penetrating peptide | 24 hours | 150 mg/kg | 8.23 ±0.07 (t1/2 β) | Rat plasma proteases | MALDI-TOF-MS | Intravenous administration in Rat | in vitro | None | None | LD50 of the conjugate administered iv in rats was between 210 and 250 mg/kg | |||
| 17682073 | 2007 | NC100668 | 13 | Acetylation | Tc chelator (NC100194) | Linear | L | Tyr residue at 8 position is Iodionated | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Tracer tested for nuclear medical imaging | 1, 1.5, 3, 6, 12, and 24 hours | 20, 100, 500, 1000, and 2000 μg | 1.2 | Human plasma proteases | LC-MS | Injected in human plasma | in vivo | None | None | Not reported | |||
| 17682073 | 2007 | NC100668 | 13 | Acetylation | Tc chelator (NC100194) | Linear | L | Tyr residue at 8 position is Iodionated | Cell penetrating peptides-Phosphorodiamidate morpholino oligomers | Tracer tested for nuclear medical imaging | 1, 1.5, 3, 6, 12, and 24 hours | 20, 100, 500, 1000, and 2000 μg | 10.5 (terminal elimination) | Human plasma proteases | LC-MS | Injected in human plasma | in vivo | None | None | Not reported | |||
| 17704241 | 2007 | FROPDOTA | 13 | Free | lys coupled to the chelator DOTA (DOTA is 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) | Linear | L | 111In radiolabeling | Somatostatin receptor-binding octreotide | Tumor-Targeting Peptide | 1, 2, 5, 15, 30, 60, and 120 min | 200 μl | 71 | Human serum proteases | Radioimmunoassay and RP-HPLC | Human serum | in vitro | None | None | The inhibition constant was 494 nM. | |||
| 18586440 | 2008 | NT pro-BNP (N-terminal pro B-type natriuretic peptide) | 76 | Free | Free | Linear | L | None | B-type Natriuretic peptide | Diuretic, Natriuretic and vasodilatory peptide | Not mentioned | Not mentioned | 120 | Human serum proteases | Not mentioned | Humans | in vivo | http://www.phoenixpeptide.com/catalog/product_info | None | NT-pro-BNP (using a cutoff value of >308 pg/mL) is an independent predictor of postoperative myocardial injury in patients undergoing vascular surgery | |||
| 16828890 | 2006 | NC-1900 (Analogue of arginine vasopressin) | 5 | Free | Addition of lycinamide | Linear | L | pGlu=pyroglutamic acid | Synthetic analogue of arginine vasopressin | Neuropeptide | 0.5, 1, 2, 3, 4, 6, 9, 12, 24, 36 and 48 h | 0.55mM | 19 | Mice blood proteases | HPLC-UV | Subcutaneously and Intravenously injected in mice | in vitro | None | None | Single subcutaneous injection of NC-1900 tended to improve the scopolamine-induced memory deficits, but the effects were far from enough to make the animals €™ memory recover, which suggested that either a higher dose or multi- injections of NC-1900 were needed to promote its effects | |||
| 16828890 | 2006 | NC-1900 (Analogue of arginine vasopressin) | 5 | Free | Addition of lycinamide | Linear | L | conjugated with cationic bovine serum albumin conjugated pegylated nanoparticles (CBSA-NPs), pGlu=pyroglutamic acid | Synthetic analogue of arginine vasopressin | Neuropeptide | 0.5, 1, 2, 3, 4, 6, 9, 12, 24, 36 and 48 h | 0.55mM | 78 | Mice blood proteases | HPLC-UV | Subcutaneously and Intravenously injected in mice | in vitro | None | None | The memory impairments were greatly improved, and then to normal when the mice were treated with NC-1900 loaded in CBSA-NPs | |||
| 17283237 | 2007 | Glucagon like peptide-1 (GLP-1) | 37 | Free | Free | Linear | L | None | Human GLP-1 | Growth Hormone | 3 hours | 100 μg/kg peptide in mice | <5 | Mice blood proteases | Radioimmunoassay | Subcutaneously injected in mice | in vivo | http://www.uniprot.org/blast/?about=P01275[92-128] | None | Promotes glucose-depen- dent insulin secretion from the pancreas | |||
| 17258819 | 2007 | Vasopressin, 8-L-Arginine | 9 | Free | Free | Cyclic (C1-C6) | L | I125 labeling | Human Vasopressin | Anti-diuretic peptide | 20, 40 seconds and1, 2, 4, 8, 16, 32 and 60 min | 15 μCi (555 kBq) | 1.06 ±0.19 (fast phase) | Rat blood proteases | Radioimmunoassay | Female homozygous Brattleboro rats and male Wistar rats | in vivo | http://www.polypeptide.com/vasopressin-8-l-arginin | None | antidiuretic activity 408 IU/mg | |||
| 17258819 | 2007 | Vasopressin, 8-L-Arginine | 9 | Free | Free | Cyclic (C1-C6) | L | I125 labeling | Human Vasopressin | Anti-diuretic peptide | 20, 40 seconds and1, 2, 4, 8, 16, 32 and 60 min | 15 μCi (555 kBq) | 5.96 ±0.58 (slow phase) | Rat blood proteases | Radioimmunoassay | Female homozygous Brattleboro rats and male Wistar rats | in vivo | http://www.polypeptide.com/vasopressin-8-l-arginin | None | antidiuretic activity 408 IU/mg | |||
| 17258819 | 2007 | Vasopressin, 8-L-Arginine | 9 | Free | Free | Cyclic (C1-C6) | L | I125 labeling | Human Vasopressin | Anti-diuretic peptide | 20, 40 seconds and1, 2, 4, 8, 16, 32 and 60 min | 15 μCi (555 kBq) | 1.00 ±0.15 (fast phase) | Rat blood proteases | Radioimmunoassay | Female homozygous Brattleboro rats and male Wistar rats along with OPC-31260 | in vivo | http://www.polypeptide.com/vasopressin-8-l-arginin | None | antidiuretic activity 408 IU/mg | |||
| 17258819 | 2007 | Vasopressin, 8-L-Arginine | 9 | Free | Free | Cyclic (C1-C6) | L | I125 labeling | Human Vasopressin | Anti-diuretic peptide | 20, 40 seconds and1, 2, 4, 8, 16, 32 and 60 min | 15 μCi (555 kBq) | 8.90 ±0.37 (slow phase) | Rat blood proteases | Radioimmunoassay | Female homozygous Brattleboro rats and male Wistar rats along with OPC-31261 | in vivo | http://www.polypeptide.com/vasopressin-8-l-arginin | None | antidiuretic activity 408 IU/mg | |||
| 17684103 | 2007 | 125I-vasopressin | 9 | Free | Free | Cyclic (C1-C6) | L | I125 labeling | Human Vasopressin | Anti-diuretic peptide | 1,2 and 3 minutes | 50 or 0.4 pmol of vasopressin with 33 kBq | ~ 1.5 | Mice blood proteases | Radioimmunoassay | Saline treated IRAP+/+ mice | in vivo | http://www.polypeptide.com/vasopressin-8-l-arginin | None | antiduretic activity | |||
| 17684103 | 2007 | 125I-vasopressin | 9 | Free | Free | Cyclic (C1-C6) | L | I125 labeling | Human Vasopressin | Anti-diuretic peptide | 1,2 and 3 minutes | 50 or 0.4 pmol of vasopressin with 33 kBq | 1 | Mice blood proteases | Radioimmunoassay | Insulin-treated IRAP+/+ mice | in vivo | http://www.polypeptide.com/vasopressin-8-l-arginin | None | antiduretic activity | |||
| 17684103 | 2007 | 125I-vasopressin | 9 | Free | Free | Cyclic (C1-C6) | L | I125 labeling | Human Vasopressin | Anti-diuretic peptide | 1,2 and 3 minutes | 50 or 0.4 pmol of vasopressin with 33 kBq | 3 | Mice blood proteases | Radioimmunoassay | Insulin-treated IRAP-/- mice. | in vivo | http://www.polypeptide.com/vasopressin-8-l-arginin | None | antiduretic activity | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 0.138 mg/kg | 23.1 ±4.3 | Rat plasma proteases | Competitive ELISA | Rat plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 0.69mg/kg | 21.5 ±3.6 | Rat plasma proteases | Competitive ELISA | Rat plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 1.38 mg/kg | 22.2 ±1.7 | Rat plasma proteases | Competitive ELISA | Rat plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 6.9 mg/kg | 27.5 ±3.7 | Rat plasma proteases | Competitive ELISA | Rat plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 13.8 mg/kg | 30.7 ±2.6 | Rat plasma proteases | Competitive ELISA | Rat plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 9.87 mg/kg | 47.8 | Rat plasma proteases(rat chronic renal insufficiency (CRI) model) | Competitive ELISA | Rat(rat chronic renal insufficiency (CRI) model) plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 0.02 mg/kg | 14.6 ±4.3 | Monkey plasma proteases | Competitive ELISA | Monkey plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 0.1 mg/kg | 16.4 ±1.7 | Monkey plasma proteases | Competitive ELISA | Monkey plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 0.475 mg/kg | 29.9 ±9.4 | Monkey plasma proteases | Competitive ELISA | Monkey plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 16982323 | 2006 | Hematide | 42 | Acetylation | Beta-alanine-PEG | Linear | L | X1-Napthyl-alanine, X2-Sarcosine | Synthetic dimeric peptide | Erythropoiesis stimulating agent | Not mentioned | 1.35 mg/kg | 59.7 ±2.9 | Monkey plasma proteases | Competitive ELISA | Monkey plasma (Dose i/v adminstered) | in vivo | None | None | IC50 = 37pM for HuEPOr/125I-EPO competition binding assay, EC50 =460 pM for cell proliferation stimulation | |||
| 17408666 | 2007 | Cydiastatin 4 | 8 | Free | Amidation | Linear | L | None | Synthetic | Neuropeptides | 30 °C for 20 minutes | 1nmol | 16.5 | M. sexta larval midgut tissue proteases | RP-HPLC | Midgut tissues of M. sexta | in vitro | None | None | Not reported | |||
| 17408666 | 2007 | Cydiastatin 5 | 8 | Free | Amidation | Linear | L | None | Synthetic | Neuropeptides | 30 °C for 20 minutes | 1nmol | 2.5 | M. sexta larval midgut lumen proteases | RP-HPLC | Midgut Lumen of M. sexta | in vitro | None | None | Not reported | |||
| 17408666 | 2007 | Cydiastatin 4-alpha | 13 | Free | Amidation | Linear | L | None | Synthetic | Neuropeptides | 30 °C for 20 minutes | 1nmol | 71 | M. sexta larval midgut tissue extract proteases | RP-HPLC | Midgut tissues of M. sexta | in vitro | None | None | Not reported | |||
| 17408666 | 2007 | Cydiastatin 4-alpha | 13 | Free | Amidation | Linear | L | None | Synthetic | Neuropeptides | 30 °C for 20 minutes | 1nmol | 4.5 | M. sexta larval midgut lumen proteases | RP-HPLC | Midgut lumen of M. sexta | in vitro | None | None | Not reported | |||
| 17408666 | 2007 | Cydiastatin 4-alpha | 13 | Free | Amidation | Linear | L | None | Synthetic | Neuropeptides | 31 °C for 20 minutes | 1nmol | 52 | M. sexta haemolymph proteases | RP-HPLC | Haemolymph of M. sexta | in vitro | None | None | Not reported | |||
| 17408666 | 2007 | Cydiastatin 4-alpha | 12 | Free | Amidation | Linear | L | Acpc=cyclopropylalanine | Synthetic | Neuropeptides | 30 °C for 20 minutes | 1nmol | 116 | M. sexta larval midgut tissue proteases | RP-HPLC | Midgut tissue | in vitro | None | None | Not reported | |||
| 17408666 | 2007 | Cydiastatin 4-alpha | 12 | Free | Amidation | Linear | L | Acpc=cyclopropylalanine | Synthetic | Neuropeptides | 30 °C for 20 minutes | 1nmol | 7.5 | M. sexta larval midgut lumen proteases | RP-HPLC | Midgut lumen | in vitro | None | None | Not reported | |||
| 17498958 | 2007 | Thyrotropin-releasing hormone (TRH) | 3 | Free | Amidation | Linear | L | Pyr=pyroglutamic acid | Hypothalamus | Stimulates the release TSH(thyroid-stimulating hormone) by pitutiary gland | 37 °C for 1-120 minutes | 200μM | ~3 | Homogenate of Caco-2 cells proteases | LC-MS | Homogenate of Caco-2 cells | in vitro | None | None | Not reported | |||
| 17498958 | 2007 | Peptide1 (Thyrotropin-releasing hormone (TRH) analogue) | 3 | Free | D-glucopyranuronamide | Linear | L | Pyr=pyroglutamic acid | Synthetic derived from TRH | Stimulates the release TSH(thyroid-stimulating hormone) by pitutiary gland | 37 °C for 1-120 minutes | 200μM | ~20 | Homogenate of Caco-2 cells proteases | LC-MS | Homogenate of Caco-2 cells | in vitro | None | None | Not reported | |||
| 17498958 | 2007 | Peptide2 (Thyrotropin-releasing hormone (TRH) analogue) | 3 | 2-aminooctanoic acid | D-glucopyranuronamide | Linear | L | None | Synthetic derived from TRH | Stimulates the release TSH(thyroid-stimulating hormone) by pitutiary gland | 37 °C for 1-120 minutes | 200μM | ~20 | Homogenate of Caco-2 cells proteases | LC-MS | Homogenate of Caco-2 cells | in vitro | None | None | Not reported | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 3.2mg/kg | 8.15 ±1.97 ( alpha or distribution half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 6.4mg/kg | 9.69 ±1.5 ( alpha or distribution half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 12.8mg/kg | 8.56 ±2.01 ( alpha or distribution half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 3.2mg/kg | 24.74 ±8.30 ( beta or elimination half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 6.4mg/kg | 27.38 ±11.52 ( beta or elimination half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 12.8mg/kg | 30.49 ±10.24 ( beta or elimination half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 3.2mg/kg | 1.45 ±0.53(gamma or termination elimination half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 6.4mg/kg | 1.30 ±0.27 (gamma or termination elimination half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 18049308 | 2007 | HLP(Hirulog-like peptide) | 32 | Free | Free | Linear | L | I125 labeling | Synthetic | Thrombin inhibitor | Blood collected after 2-120 minutes after i/v injection of peptide | 12.8mg/kg | 1.24 ±0.44 (gamma or termination elimination half life) | Rat plasma proteases | Radioisotopic tracing method | Rat plasma | in vivo | None | None | Platelet aggregation %age = 24.33 ± 8.12, 25.67 ± 10.01 , 30.17 ± 1.13 for 3.2mg/kg/h . 2.3mg/kg/h 1.6 mg/kg/h respectively as compre to control which 36.67 ± 3.44 %; Therefore, bleeding time was significantly longer in rats received 1.6, 2.3, or 3.2 mg/kg/h of HLP compared to control | |||
| 17532097 | 2007 | N/OFQ (Nociceptin/Orphanin FQ peptide receptor) | 17 | Free | Free | Linear | L | None | Derived from the prepronociceptin protein | NOP-Receptor ligands | 37 °C for 240 min | 6 μg/μl | 64 ±1 | Mouse plasma proteases | RP-HPLC | Mouse Plasma | in vitro | None | None | Hypotensive and bradycardic effects evoked by N/OFQ after i.v. administration in rats, was lasting (about 10 min) | |||
| 17532097 | 2007 | N/OFQ (Nociceptin/Orphanin FQ peptide receptor) | 17 | Free | Free | Linear | L | None | Derived from the prepronociceptin protein | NOP-Receptor ligands | 37 °C for 240 min | 6 μg/μl | 3.2 ±1.8 | Mouse brain homogenate proteases | RP-HPLC | Mouse brain homogenate | in vitro | None | None | Hypotensive and bradycardic effects evoked by N/OFQ after i.v. administration in rats, was lasting (about 10 min) | |||
| 17532097 | 2007 | UFP-112 (Nociceptin/Orphanin FQ receptor antagonist) | 17 | Free | Amidation | Linear | L | (pF)F = p-flouro Phenylalanine; Aib= 2-Aminoisobutyric acid | Synthetic | NOP-Receptor ligands | 37 °C for 240 min | 6 μg/μl | 11.3 ±1.4 | Mouse brain homogenate proteases | RP-HPLC | Mouse brain homogenate | in vitro | 20497197 | None | Hypotensive and bradycardic effects evoked by UFP-112 after i.v. administration in rats wast lasting for (i.e. 80 min | |||
| 17532097 | 2007 | UFP-112 (Nociceptin/Orphanin FQ receptor antagonist) | 17 | Free | Amidation | Linear | L | (pF)F = p-flouro Phenylalanine; Aib= 2-Aminoisobutyric acid | Synthetic | NOP-Receptor ligands | 37 °C for 240 min | 6 μg/μl | 167 ±9 | Mouse plasma proteases | RP-HPLC | Mouse Plasma | in vitro | 20497197 | None | Hypotensive and bradycardic effects evoked by UFP-112 after i.v. administration in rats wast lasting for (i.e. 80 min | |||
| 18249125 | 2009 | Prostate Specific Antigen (Prodrug 2) | 6 | Mu (Morpholino) | Cyclopamine | Linear | L | None | Synthetic | Prostate-specific antigen (PSA)-activated prodrugs against prostate cancer | 0.5-18 hours at room temperature | 100 µM | 22 | PSA enzymes | Hydrolysis and RP-HPLC | NA | in vitro | None | None | Not reported | |||
| 18249125 | 2009 | Prostate Specific Antigen (Prodrug 3) | 5 | Mu (Morpholino) | Cyclopamine | Linear | L | None | Synthetic | Prostate-specific antigen (PSA)-activated prodrugs against prostate cancer | 0.5-18 hours at room temperature | 100 µM | 3.2 | PSA enzymes | Hydrolysis and RP-HPLC | NA | in vitro | None | None | Not reported | |||
| 18697865 | 2008 | Ghrelin | 28 | Free | Free | Linear | L | n-octanoyl group at ser 3 | Secreted by stomach P/D1-type cells | Stimulates apetite and GH secretion | Blood collected after 20 minutes to 2200 h after i/v injection of peptide | 1 µg/kg i/v injected | 21 ±3.0 | Human plasma proteases | Competitive Radioimmunoassay | Human plasma | in vivo | 15788704 | None | Not reported | |||
| 18697865 | 2008 | Ghrelin | 28 | Free | Free | Linear | L | n-octanoyl group at ser 3 | Secreted by stomach P/D1-type cells | Stimulates apetite and GH secretion | Blood collected after 20 minutes to 2200 h after i/v injection of peptide | 3 µg/kg i/v injected | 45 | Human plasma proteases | Competitive Radioimmunoassay | Human plasma | in vivo | 15788704 | None | Not reported | |||
| 18972837 | 2008 | sCT (Salmon calcitonin) | 32 | Free | Free | Cyclic (C1-C7) | L | None | Hormone secreted by the parafollicular cells of thethyroid gland | Calcitropic Hormone, reduce blood calcium | 5-360minutes | 10 µM | 13.18 | Rat kidney homogenates proteases | LC-ESI-MS | Rat kidney homogenates | in vitro | None | None | Not reported | |||
| 18972837 | 2008 | sCT (Salmon calcitonin) | 32 | Free | Free | Cyclic (C1-C7) | L | None | Hormone secreted by the parafollicular cells of thethyroid gland | Calcitropic Hormone, reduce blood calcium | 5-360minutes | 10 µM | 43.07 | Rat kidney homogenates proteases | LC-ESI-MS | Rat Liver homogenates | in vitro | None | None | Not reported | |||
| 19770015 | 2009 | VrAPI (Aspartic protease inhibitor in seeds of V. radiata) | 15 | Free | Free | Linear | L | None | From plant Vigna radiata | Protease inhibitor | pH 2-10, Temp 20-100 °C | 2mg -5mg at pH 3 and temperature 100 | ~30 | None | Bradford assay | Buffer | in vitro | None | None | Total (aspartic protease) activity 2516 U | |||
| 18632826 | 2008 | 99m Tc-Duramycin | 19 | Free | Free | Linear | L | Succinimidyl 6-hydrazinonicotinate acetone hydrazone (HYNIC) derivatized, HYNIC conjugated at either at Cys -1 or Amine group Of Lys-2 | Phosphatidylethanolamine binding probe and employed in In Vivo Imaging of Acute Cardiac Cell Death | Molecular probe for imaging PtdE | Blood sample collected at 1-60 minutes | 2.3nmol | <4 | Rat blood proteases | HPLC radiodetection (radio-HPLC) | Healthy Sprague €“Dawley rats blood | in vivo | None | None | Binding of 99mTc-duramycin to apoptotic cells was elevated by a factor of 32 ± 6 | |||
| 19344673 | 2009 | Mouse [D-Leu-4]OB3 | 7 | Free | Free | Linear | Mix | None | Synthetic peptide amide with leptin-like activity | Regulate energy balance by inhibiting hunger | Blood collected after 5-120 minutes after peptide delivery | 1mg/200ul | 30 | Mice serum proteases | Competitive ELISA | Male Swiss Webster mice serum (Intraperitoneal route of delivery) | in vivo | 11495687 | None | Not reported | |||
| 19344673 | 2009 | Mouse [D-Leu-4]OB3 | 7 | Free | Free | Linear | Mix | None | Synthetic peptide amide with leptin-like activity | Regulate energy balance by inhibiting hunger | Blood collected after 5-120 minutes after peptide delivery | 1mg/200ul | 35 | Mice serum proteases | Competitive ELISA | Male Swiss Webster mice serum (Subcutaneous Route of delivery) | in vivo | 11495687 | None | Not reported | |||
| 19344673 | 2009 | Mouse [D-Leu-4]OB3 | 7 | Free | Free | Linear | Mix | None | Synthetic peptide amide with leptin-like activity | Regulate energy balance by inhibiting hunger | Blood collected after 5-120 minutes after peptide delivery | 1mg/200ul | 42 | Mice serum proteases | Competitive ELISA | Male Swiss Webster mice serum (Intra-muscular route of delivery) | in vivo | 11495687 | None | Not reported | |||
| 19344673 | 2009 | Mouse [D-Leu-4]OB3 | 7 | Free | Free | Linear | Mix | None | Synthetic peptide amide with leptin-like activity | Regulate energy balance by inhibiting hunger | Blood collected after 5-120 minutes after peptide delivery | 1mg/200ul | 41.1 | Mice serum proteases | Competitive ELISA | Male Swiss Webster mice serum (Intranasal route of delivery) | in vivo | 11495687 | None | Not reported | |||
| 19157421 | 2009 | Glypromate | 3 | Free | Free | Linear | L | None | N-terminal cleavage product of human insulin-like growth factor-1 (IGF-1) in the brain | Neuroprotective | Blood collected after 0.5-12 hours after peptide delivery | 3 -10 mg/kg/h dose | 5 | Rat plasma proteases | LC-MS | Sprague-Dawley rats plasma (Dose i/v injected) | in vivo | None | None | Not reported | |||
| 19157421 | 2009 | NNZ-2566 (Glycyl-L-2-methylprolyl-L- glutamic acid) | 3 | Free | Free | Linear | L | Methylation of alpha-C of Pro | Glypromate analogue | Neuroprotective | Blood collected after 0.5-12 hours after peptide delivery | 3 -10 mg/kg/h dose | 49 | Rat blood proteases | LC-MS | Sprague-Dawley rats brain (Dose i/v injected) | in vivo | None | None | NNZ-2566-treated animals(i/v) exhibited an average infarct area of 79.8 ±10.4 mm2 (3 mg/kg/h, pb0.01) and 21.3 ±7.5 mm2 (10 mg/kg/h) as compare to ET-1 induced an infarct area of 153.1 ±20.1 mm2 (mean ±s.e.m) in saline-treated rat; Total injury size was 22.2 ±5.7 mm2 following 30 mg/kg (76% protection; Dunnett's multiple comparison test) and only 4.6 ±2.3 mm2 following 60 mg/kg (95% protection; Dunnett's multiple comparison test). | |||
| 19157421 | 2009 | NNZ-2566 (Glycyl-L-2-methylprolyl-L- glutamic acid) | 3 | Free | Free | Linear | L | Methylation of alpha-C of Pro | Glypromate analogue | Neuroprotective | Blood collected after 0.5-12 hours after peptide delivery | 3 -10 mg/kg/h dose | 74 | Rat brain proteases | LC-MS | Sprague-Dawley rats blood (Dose i/v injected) | in vivo | None | None | NNZ-2566-treated animals(i/v) exhibited an average infarct area of 79.8 ±10.4 mm2 (3 mg/kg/h, pb0.01) and 21.3 ±7.5 mm2 (10 mg/kg/h) as compare to ET-1 induced an infarct area of 153.1 ±20.1 mm2 (mean ±s.e.m) in saline-treated rat; Total injury size was 22.2 ±5.7 mm2 following 30 mg/kg (76% protection; Dunnett's multiple comparison test) and only 4.6 ±2.3 mm2 following 60 mg/kg (95% protection; Dunnett's multiple comparison test). | |||
| 18424366 | 2008 | GLP(7-34) (Glucagon like peptide) | 28 | Acetylation | Amidation | Linear | L | None | GLP-1 (Glucagon like peptide-1) analogue | Antihyperglycemic or incretin effect (Stimulate Insulin release in glucose dependent manner) | 37C for 2 hours | 200 µg/ml | >2 | DPP IV | MALDI-TOF-MS | Peptide in 0.01 M Na2HPO4 buffer | in vitro | None | None | In the DPP-IV-free rat pancreatic beta cell line RINm5F GLP-1-(7-34)-amide elevated cAMP production with an EC50 of about 40 nM | |||
| 18424366 | 2008 | GLP(7-34) (Glucagon like peptide) | 28 | Acetylation | Amidation | Linear | L | None | GLP-1 (Glucagon like peptide-1) analogue | Antihyperglycemic or incretin effect (Stimulate Insulin release in glucose dependent manner) | 37C for 2 hours | 200 µg/ml | ~34 | DPP IV | MALDI-TOF-MS | Peptide in 0.01 M Na2HPO4 buffer | in vitro | None | None | In the DPP-IV-free rat pancreatic beta cell line RINm5F GLP-1-(7-34)-amide elevated cAMP production with an EC50 of about 40 nM | |||
| 20158487 | 2010 | PEG10kDa-[(123)I]-CCK-10 | 10 | Free | Amidation | Linear | L | SO3H Group at Tyr-4, Coupled to PEG(10KDa), PEG=Polyethylene glycol, CCK-10=Cholecystokinin | Peptide Hormone produced by small intestine | Stimulates the digestion of fat and protein | Not mentioned | Not available | 8 (Elimination half life t1/2 alpha) | Rat blood proteases | HPLC | Rat blood | in vivo | None | None | Not reported | |||
| 20158487 | 2010 | PEG10kDa-[(123)I]-CCK-10 | 10 | Free | Amidation | Linear | L | SO3H Group at Tyr-4, Coupled to PEG(10KDa), PEG=Polyethylene glycol, CCK-10=Cholecystokinin | Peptide Hormone produced by small intestine | Stimulates the digestion of fat and protein | Not mentioned | Not available | 15 | Rat blood proteases | HPLC | Rat blood | in vivo | None | None | Not reported | |||
| 20221650 | 2010 | R1(NH2GR11) (An arginine-rich cell permeable peptide) | 15 | Cu-DOTA (DOTA=1,4,7,10- tetraazacyclododecane-1,4,7,10-tetraacetic acid) | Free | Linear | L | Cu-labelled | Derived from prostate cancer cell lines, an arginine-rich cell permeable peptide | Cell permeable peptide | Not mentioned | Not available | 10.7 | Proteases from mouse blood | Fluorescence Imaging | Mouse blood | in vivo | None | None | In PC3, LNCaP, PZ-HPV-7, DU145 and DU145, FITC-NHGR11 displayed much higher uptake efficiency | |||
| 20221650 | 2010 | R1(NH2GR11) (An arginine-rich cell permeable peptide) | 15 | Cu-DOTA (DOTA=1,4,7,10- tetraazacyclododecane-1,4,7,10-tetraacetic acid) | Free | Linear | L | Cu-labelled | Derived from prostate cancer cell lines, an arginine-rich cell permeable peptide | Cell permeable peptide | Not mentioned | Not available | 17.2 (Elimination half life) | Proteases from mouse blood | Fluorescence Imaging | Mouse blood | in vivo | None | None | In PC3, LNCaP, PZ-HPV-7, DU145 and DU145, FITC-NHGR11 displayed much higher uptake efficiency | |||
| 19023544 | 2008 | Tα1-TP5 (Thymosin α1-thymopentin) | 33 | Acetylation | Free | Linear | L | None | Synthetic | Immunoregulatory | Not mentioned | Not mentioned | 140 ±14 | Rabbit plasma proteases | HPLC | Heparinized rabbit plasma | in vitro | http://www.drugbank.ca/drugs/DB00110 | None | IL2 concentration in mouse serum:0.75pg/ml,macrophage clearance index(K value)=0.0206 ±0.0010,phagocytic index(α value=3.95 ±0.19(compared to TP5). | |||
| 19023544 | 2008 | Tα1 (Thymosin α1) | 28 | Acetylation | Free | Linear | L | None | Component of thymosin fraction | Immunomodulator | Not mentioned | Not mentioned | 127 ±11 | Rabbit plasma proteases | HPLC | Heparinized rabbit plasma | in vitro | http://www.drugbank.ca/drugs/DB00111 | None | IL2 concentration in mouse serum:0.7pg/ml,macrophage clearance index(K value)=0.0165 ±0.0007,phagocytic index(α value=3.73 ±0.56. | |||
| 19023544 | 2008 | TP5 (Thymopentin) | 5 | Free | Free | Linear | L | None | Synthetic peptide of thymic hormone | Immunomodulator | Not mentioned | Not mentioned | 5.6 ±0.7 | Rabbit plasma proteases | HPLC | heparinized rabbit plasma | in vitro | http://www.drugbank.ca/drugs/DB00112 | None | IL2 concentration in mouse serum:0.65pg/ml,macrophage clearance index(K value)=0.0132 ±0.0008,phagocytic index(α value=3.43 ±0.29. | |||
| 20382695 | 2010 | hGLP-1[7-36] (Human glucagon like peptide-1) | 30 | Free | Amidation | Linear | L | None | Incretin released by intestinal L cells | Metabolism regulation | 1 hour | 40 nm(1μg/μl upto 500μl) | 50 | Rat blood proteases | HPLC | Rat blood plasma | in vitro | http://www.drugbank.ca/drugs/DB00113 | None | cAMP stimulation,EC50=0.08nM | |||
| 20382695 | 2010 | Taspoglutide | 30 | Free | Amidation | Linear | L | Aib=α-aminoisobutyric acid replacing Ala8 and Gly35 of hGLP-1[7-36] | Novel analog of hGLP1 | Treatment of type 2 diabetes(clinical trials) | 1 hour | 40 nm(1μg/μl upto 500μl) | 9.8 | Rat blood proteases | HPLC | Rat blood plasma | in vitro | http://www.drugbank.ca/drugs/DB00114 | None | cAMP stimulation,EC50=0.06nM | |||
| 20687610 | 2010 | GLP-1 (glucagon like peptide-1) | 30 | Free | Free | Linear | L | None | Incretin released by intestinal L cells | Glucose dependent insulin secretion,promotion of insulin gene transcription,stimulation of β-cell proliferation and neogenesis, inhibition of β-cell apoptosis, and suppression of glucagon secretion. | 24 hours | 100μM | 2.0 ±0.2 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00115 | None | EC50=4.6nM,pEC50=8.3 ±0.08 | |||
| 20687610 | 2010 | c[E16,K20]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16 and K20) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 1.8 ±0.3 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00116 | None | EC50=3.8nM,pEC50=8.4 ±0.06 | |||
| 20687610 | 2010 | c[E18,K22]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E18 and K22) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 2.1 ±0.4 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00117 | None | EC50=0.6nM,pEC50=9.2 ±0.11 | |||
| 20687610 | 2010 | c[E22,K26]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E22 and K26) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 2.9 ±0.8 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00118 | None | EC50=2.8nM,pEC50=8.3 ±0.03 | |||
| 20687610 | 2010 | c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E30 and K34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 3.3 ±0.4 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00119 | None | EC50=5.3nM,pEC50=8.6 ±0.13 | |||
| 20687610 | 2010 | c[E16,K20]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20 and E30-K34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 3.1 ±0.1 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00120 | None | EC50=3.3nM,pEC50=8.5 ±0.04 | |||
| 20687610 | 2010 | c[K16,E20]-c[K30,E34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between K16-E20 and K30-E34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 2.9 ±0.1 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00121 | None | EC50=7.0nM,pEC50=8.2 ±0.11 | |||
| 20687610 | 2010 | c[E18,K22]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E18-K22 and E30-K34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 3.6 ±0.2 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00122 | None | EC50=1.9nM,pEC50=8.7 ±0.14 | |||
| 20687610 | 2010 | c[K18,E22]-c[K30,E34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between K18-E22 and K30-E34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 4.1 ±0.2 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00123 | None | EC50=1.0nM,pEC50=9.0 ±0.09 | |||
| 20687610 | 2010 | c[E22,K26]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E22-K26 and E30-K34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 6.0 ±1.8 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00124 | None | EC50=1.6nM,pEC50=8.8 ±0.11 | |||
| 20687610 | 2010 | c[K22,E26]-c[K30,E34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between K22-E26 and K30-E34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 7.3 ±0.4 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00125 | None | EC50=2.2nM,pEC50=8.7 ±0.14 | |||
| 20687610 | 2010 | c[E16,K20]-c[E22,K26]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K34) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | >24 | Dipeptidyl peptidase-IV | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00126 | None | EC50=1.8nM,pEC50=8.7 ±0.09 | |||
| 20687610 | 2010 | c[E16,K20]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K35) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 4.6 ±0.7 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human DPP-IV enzyme (0.2 ng/mL) in Tris buffer (25 mM, pH 8.0) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00127 | None | EC50=3.8nM,pEC50=8.4 ±0.06 | |||
| 20687610 | 2010 | c[E18,K22]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K36) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 3.2 ±0.4 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00128 | None | EC50=0.6nM,pEC50=9.2 ±0.11 | |||
| 20687610 | 2010 | c[E22,K26]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K37) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 10 ±3.5 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00129 | None | EC50=2.8nM,pEC50=8.3 ±0.03 | |||
| 20687610 | 2010 | c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K38) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 6.9 ±0.5 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00130 | None | EC50=5.3nM,pEC50=8.6 ±0.13 | |||
| 20687610 | 2010 | c[E16,K20]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K39) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 6.9 ±0.1 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00131 | None | EC50=3.3nM,pEC50=8.5 ±0.04 | |||
| 20687610 | 2010 | c[K16,E20]-c[K30,E34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K40) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 1.7 ±5.0 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00132 | None | EC50=7.0nM,pEC50=8.2 ±0.11 | |||
| 20687610 | 2010 | c[E18,K22]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K41) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | >96 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00133 | None | EC50=1.9nM,pEC50=8.7 ±0.14 | |||
| 20687610 | 2010 | c[K18,E22]-c[K30,E34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K42) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 18 ±2.2 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00134 | None | EC50=1.0nM,pEC50=9.0 ±0.09 | |||
| 20687610 | 2010 | c[E22,K26]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K43) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 3.5 ±0.9 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00135 | None | EC50=1.6nM,pEC50=8.8 ±0.11 | |||
| 20687610 | 2010 | c[K22,E26]-c[K30,E34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K44) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | 1.2 ±0.3 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00136 | None | EC50=2.2nM,pEC50=8.7 ±0.14 | |||
| 20687610 | 2010 | c[E16,K20]-c[E22,K26]-c[E30,K34]GLP-1(7-36)-NH2 | 30 | Free | Amidation | Cyclic (Lactam bridge between E16-K20, E22-K26 and E30-K45) | L | None | Analog of GLP-1 | Diagnosis and treatment of diabetes | 24 hours | 100μM | >96 | Neutral endopeptidase 24.11 | HPLC | GLP-1 analogue (100 μM) was incubated with the recombinant human NEP 24.11 enzyme (1.0 μg/mL) in HEPES buffer (50 mM, pH 7.4, 50 mM NaCl) at 37 °C | in vitro | http://www.drugbank.ca/drugs/DB00137 | None | EC50=1.8nM,pEC50=8.7 ±0.09 | |||
| 21036718 | 2010 | 177Lu-AMBA | 9 | 177Lu,DO3A-CH2CO-G-(4-aminobenzoyl) | Amidation | Linear | L | None | Synthetic Bombesin like peptide | Clinical trials for use as systemic radiotherapy for hormone refractory prostate cancer (HRPC) patients. | Not mentioned | 10μg/mouse | 0.52 ±0.05(t1/2α) | Mice plasma proteases | Radio-HPLC | Intravenous injection in PC-3M-luc-C6 tumour-bearing mice | in vivo | http://www.drugbank.ca/drugs/DB00138 | None | In vitro stability =24.3 ±21.9% after 48 hours | |||
| 21036718 | 2010 | 177Lu-AMBA | 9 | 177Lu,DO3A-CH2CO-G-(4-aminobenzoyl) | Amidation | Linear | L | None | Synthetic Bombesin like peptide | Clinical trials for use as systemic radiotherapy for hormone refractory prostate cancer (HRPC) patients. | Not mentioned | 10μg/mouse | 26.6 ±11.7(t1/2β) | Mice plasma proteases | Radio-HPLC | Intravenous injection in PC-3M-luc-C6 tumour-bearing mice | in vivo | http://www.drugbank.ca/drugs/DB00139 | None | In vitro stability =24.3 ±21.9% after 48 hours | |||
| 17204551 | 2007 | Rat Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin frpm human | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 0 - 60 minutes | 10 μg | 22 ±2 | Protease from rat plasma | Radioimmunoassay | Intravenous injection of peptide into Sprague Dawley rats | in vivo | None | None | Co-administration of obestatin with ghrelin inhibited food intake. | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 19 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 53 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse + P8340 protease inhibitor cocktail | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 39 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse + EDTA | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 20.5 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse + Soybean trypsin inhibitor | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 20.5 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse + APMSF | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 24 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse + 1,10-Phenanthrolin | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 20 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse + Captopril | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 17 | Proteases from Crude brain homogenate of mouse | HPLC | Crude brain homogenate of mouse + Chymostatin | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 27 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 75.5 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate + P8340 protease inhibitor cocktail | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 62 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate + EDTA | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 38.5 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate + Soybean trypsin inhibitor | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 16 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate+ APMSF | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 28 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate + 1,10-Phenanthrolin | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 28 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate + Captopril | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 19422857 | 2009 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 120 minutes | 90 μg | 29.5 | Proteases from Membrane brain Homogenate | HPLC | Membrane brain Homogenate+ Chymostatin | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | No suppressive effects of obestatin on food or water intake were observed | |||
| 18602197 | 2008 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.4 | 90 μg | 42.2 [40.5, 44.0] | Proteases from mouse plasma | HPLC, LC-UV/MS | Mouse plasma | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.5 | 90 μg | 12.6 [11.4, 14.1] | Proteases from Mouse liver homogenate | HPLC, LC-UV/MS | Mouse liver homogenate | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.6 | 90 μg | 30.0 [27.8, 32.6] | Proteases from Mouse stomach homogenate | HPLC, LC-UV/MS | Mouse stomach homogenate | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Mouse Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin from mouse | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.7 | 90 μg | 138.0 [114.8, 172.9] | Proteases from Mouse kidney membrane homogenate | HPLC, LC-UV/MS | Mouse kidney membrane homogenate | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Human Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin frpm human | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.8 | 90 μg | 65.1 [59.6, 71.7] | Proteases from mouse plasma | HPLC, LC-UV/MS | Mouse plasma | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Human Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin frpm human | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.9 | 90 μg | 95.8 [89.4, 103.3] | Proteases from mouse plasma + protease inhibitor cocktai | HPLC, LC-UV/MS | Mouse plasma with protease inhibitor cocktail | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Human Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin frpm human | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.10 | 90 μg | 13.3 [12.7, 14.0] | Proteases from mouse liver homogenate | HPLC, LC-UV/MS | Mouse liver homogenate | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Human Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin frpm human | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.11 | 90 μg | 28.0 [25.8, 30.5] | Proteases from mouse liver homogenate+protease inhibitor cocktai | HPLC, LC-UV/MS | Mouse liver homogenate with protease inhibitor cocktail | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Human Obestatin | 23 | Free | Amidation | Linear | L | None | Proghrelin frpm human | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.12 | 90 μg | 67.7 [61.7, 75.1] | Proteases from mouse membrane homogenate | HPLC, LC-UV/MS | Mouse kidney membrane homogenate | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 18602197 | 2008 | Mono-iodinated human obestatin | 23 | Free | Amidation | Linear | L | Iodination at tyr16 | Proghrelin frpm human | Energy balance, Inhibit Ghrelin-induced Growth Hormone secretion | 37 °C for 0 - 60 minutes, pH 7.12 | 90 μg | 15.1 [9.1, 45.0] | Proteases from Mouse liver homogenate | HPLC, LC-UV/MS | Mouse liver homogenate | in vitro | http://www.sigmaaldrich.com/catalog/product/sigma/ | None | Not reported | |||
| 19115392 | 2009 | Interleukin-1 Receptor Antagonist (IL-1ra) | 152 | Free | Free | Cyclic(66-116) | L | Glycosylation at 84th position | Interleukin-1 Receptor Antagonist | The natural specific receptor antagonist (IL-1ra) binds to IL-1RI but does not initiate signaling as it does not engage the IL1R accessory protein and therefore acts as a receptor antagonist. | Not mentioned | Not mentioned | 6 to 15 | Rats blood proteases | Not mentioned | Rat blood | in vivo | http://www.uniprot.org/uniprot/P25086 | None | Significant depression of LTP in the group of animals that received intracerebroventricular injection of Aβ-peptide (1 €“40) compared with control animals injected with vehicle. |