Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 44. Click on ID to see further detail.
IDOV_3163Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell line22Rv1Concentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration0.01 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3164Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell line22Rv1Concentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3165Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell line22Rv1Concentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3166Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell line22Rv1Concentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration10 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3167Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration0.01 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3168Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3169Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3170Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineVCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCell proliferation kit 1 assayIn-vitro virus concentration10 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3171Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineLNCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCalcein AM assayIn-vitro virus concentration0.01 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3172Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineLNCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCalcein AM assayIn-vitro virus concentration0.1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3173Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineLNCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCalcein AM assayIn-vitro virus concentration1 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3174Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineLNCaPConcentration of cell line40000 cells per wellIn-vitro toxicityNAAssayCalcein AM assayIn-vitro virus concentration10 MOIIn-vitro result100% cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3175Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineLNCaPConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismCAnM.Cg-Foxn1nu/Crl Balb/c nude mice subcutaneous xenograft for LNCaP (5.0E+6)In-vivo virus concentration1.0E+6 pfuIn-vivo toxicityNA In-vivo resultComplete regression in tumor volume after 20 daysMode of deliveryIntraperitonealPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_3176Virus nameSemliki forest virusVirus strainSFV-VA7Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell lineLNCaPConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismCAnM.Cg-Foxn1nu/Crl Balb/c nude mice subcutaneous xenograft for LNCaP (5.0E+6)In-vivo virus concentration1.0E+6 pfuIn-vivo toxicityNA In-vivo resultComplete regression in tumor volume after 20 daysMode of deliveryIntraperitonealPathway inducedNAImmunogenic effectNAClinical trialNAPMID28557974
IDOV_5126Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result100% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5127Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result80% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5128Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result70% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5129Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result42% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5130Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result30% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5131Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result100% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5132Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result82% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5133Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result71% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5134Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result44% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5135Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine neuroblastoma cell lineCell lineNXS2Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result30% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5136Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result100% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5137Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result90% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5138Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result88% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5139Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result70% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5140Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result60% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5141Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result88% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5142Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result80% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5143Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result80% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5144Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result70% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5145Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineGL261Concentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result60% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5146Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5147Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5148Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5149Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5150Virus nameSemliki forest virusVirus strainwild type SFV4Virus genome typeRNAVirus familyAlphaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5151Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.001 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5152Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.01 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5153Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration0.1 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5154Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889
IDOV_5155Virus nameSemliki forest virusVirus strainSFVmiRTVirus genome typeRNAVirus familyAlphaviridaeVirus genome modificationInsertional mutagenesis at 3UTr for miR124, 125 and 134Virus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineMurine glioma cell lineCell lineCT-2AConcentration of cell line20000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 MOIIn-vitro result5% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectInduce production of IFN gammaClinical trialNAPMID27637889