Detailed description page of Selected OV_ID


OV_5142 details
Primary information
OV_IDOV_5142
Virus Name Semliki forest virus
StrainSFVmiRT
Virus typeRNA
Virus familyAlphaviridae
Modification in virus genomeInsertional mutagenesis at 3UTr for miR124, 125 and 134
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineMurine glioma cell line
Cell lineGL261
Concentration of cell line20000
In-vitro toxicityNA
AssayMTS assay
In-vitro virus concentration0.01 MOI
In-vitro result80% cell viability after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectInduce production of IFN gamma
Clinical trialNA
PMID27637889