Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 10. Click on ID to see further detail.
IDOV_2769Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro resultModerate cell death after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2770Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro resultModerate cell death after 36 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2771Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro resultMaximum cell death after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2772Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3 MOIIn-vitro resultModerate cell death after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2773Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3 MOIIn-vitro resultSignificant cell death after 36 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_2774Virus nameRespiratory synctial virusVirus strainwild typeVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman skin cancer cell lineCell lineA431Concentration of cell line15E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration3 MOIIn-vitro resultMaximum cell death after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMID23487261
IDOV_5887Virus nameRespiratory synctial virusVirus strainMutantVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman RWPE-1 cell lineCell lineHuman RWPE-1 cell lineConcentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration2 MOIIn-vitro resultSlight reduction in tumor growthModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMIDUS9241998
IDOV_5888Virus nameRespiratory synctial virusVirus strainMutantVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman prostate cancer cell lineCell linePC-3Concentration of cell lineNAIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration2 MOIIn-vitro result20% cell survived after treatmentModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMIDUS9241998
IDOV_5889Virus nameRespiratory synctial virusVirus strainMutantVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismAthymic nude mice xenograft for PC-3 (3.0E+6), below earIn-vivo virus concentration1.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume reduced to 200mm after 38 days compared to control 1200mmMode of deliveryIntratumoralPathway inducedInduction of apoptosis as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMIDUS9241998
IDOV_5890Virus nameRespiratory synctial virusVirus strainMutantVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismAthymic nude mice xenograft for PC-3 (3.0E+6), below earIn-vivo virus concentration1.0E+6 pfuIn-vivo toxicityNA In-vivo resultTumor volume reduced to 300mm after 35 days compared to control 900mmMode of deliveryIntratumoralPathway inducedInduction of apoptosis as measured by TUNEL assayImmunogenic effectNAClinical trialNAPMIDUS9241998