Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 10. Click on ID to see further detail.
IDOV_2769 | Virus nameRespiratory synctial virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman skin cancer cell line | Cell lineA431 | Concentration of cell line15E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro resultModerate cell death after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23487261 |
IDOV_2770 | Virus nameRespiratory synctial virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman skin cancer cell line | Cell lineA431 | Concentration of cell line15E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro resultModerate cell death after 36 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23487261 |
IDOV_2771 | Virus nameRespiratory synctial virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman skin cancer cell line | Cell lineA431 | Concentration of cell line15E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro resultMaximum cell death after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23487261 |
IDOV_2772 | Virus nameRespiratory synctial virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman skin cancer cell line | Cell lineA431 | Concentration of cell line15E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro resultModerate cell death after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23487261 |
IDOV_2773 | Virus nameRespiratory synctial virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman skin cancer cell line | Cell lineA431 | Concentration of cell line15E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro resultSignificant cell death after 36 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23487261 |
IDOV_2774 | Virus nameRespiratory synctial virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman skin cancer cell line | Cell lineA431 | Concentration of cell line15E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro resultMaximum cell death after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23487261 |
IDOV_5887 | Virus nameRespiratory synctial virus | Virus strainMutant | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman RWPE-1 cell line | Cell lineHuman RWPE-1 cell line | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro resultSlight reduction in tumor growth | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMIDUS9241998 |
IDOV_5888 | Virus nameRespiratory synctial virus | Virus strainMutant | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman prostate cancer cell line | Cell linePC-3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result20% cell survived after treatment | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMIDUS9241998 |
IDOV_5889 | Virus nameRespiratory synctial virus | Virus strainMutant | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismAthymic nude mice xenograft for PC-3 (3.0E+6), below ear | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 200mm after 38 days compared to control 1200mm | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMIDUS9241998 |
IDOV_5890 | Virus nameRespiratory synctial virus | Virus strainMutant | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismAthymic nude mice xenograft for PC-3 (3.0E+6), below ear | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 300mm after 35 days compared to control 900mm | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMIDUS9241998 |