Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 4. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5898Vaccinia virusVVTK-FCU1DNAPoxviridaeDefective in J2R gene, expressing FCU1 gene, defective in I4L geneNoVirus in combination with 5FU (100mg/kg)NoNANANANANANANANASwiss nude mice xenograft for LoVo cell line (5.0E+6)1.0E+7 pfuNA Tumor volume reduced to nearly 1000mm compared to control 2400mmIntravenouslyNANANAUS9687515
OV_5899Vaccinia virusVVTK-FCU1DNAPoxviridaeDefective in J2R gene, expressing FCU1 gene, defective in F4L geneNoVirus in combination with 5FU (100mg/kg)NoNANANANANANANANASwiss nude mice xenograft for LoVo cell line (5.0E+6)1.0E+7 pfuNA Tumor volume reduced to below 1000mm compared to control 2400mmIntravenouslyNANANAUS9687515
OV_5900Vaccinia virusVVTK-FCU1DNAPoxviridaeDefective in J2R gene, expressing FCU1 gene, defective in I4L geneYesNoNoNANANANANANANANASwiss nude mice xenograft for U87MG(5.0E+6)1.0E+7 pfuNA Tumor volume reduced to below 500mm comapred to control 3500mm after 60 daysIntravenouslyNANANAUS9687515
OV_5901Vaccinia virusVVTK-FCU1DNAPoxviridaeDefective in J2R gene, expressing FCU1 gene, defective in I4L geneNoVirus in combination with 5FU (100mg/kg)NoNANANANANANANANASwiss nude mice xenograft for U87MG(5.0E+6)1.0E+7 pfuNA Tumor volume reduced to below 500mm comapred to control 3500mm after 60 daysIntravenouslyNANANAUS9687515