The total number of records retrieved from this search are 4. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_5898	Virus nameVaccinia virus	Virus strainVVTK-FCU1	Virus genome typeDNA	Virus familyPoxviridae	Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in I4L gene	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with 5FU (100mg/kg)	Immune gene insertion in viral genomeNo	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismSwiss nude mice xenograft for LoVo cell line (5.0E+6)	In-vivo virus concentration1.0E+7 pfu	In-vivo toxicityNA	In-vivo resultTumor volume reduced to nearly 1000mm compared to control 2400mm	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS9687515
IDOV_5899	Virus nameVaccinia virus	Virus strainVVTK-FCU1	Virus genome typeDNA	Virus familyPoxviridae	Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in F4L gene	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with 5FU (100mg/kg)	Immune gene insertion in viral genomeNo	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismSwiss nude mice xenograft for LoVo cell line (5.0E+6)	In-vivo virus concentration1.0E+7 pfu	In-vivo toxicityNA	In-vivo resultTumor volume reduced to below 1000mm compared to control 2400mm	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS9687515
IDOV_5900	Virus nameVaccinia virus	Virus strainVVTK-FCU1	Virus genome typeDNA	Virus familyPoxviridae	Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in I4L gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismSwiss nude mice xenograft for U87MG(5.0E+6)	In-vivo virus concentration1.0E+7 pfu	In-vivo toxicityNA	In-vivo resultTumor volume reduced to below 500mm comapred to control 3500mm after 60 days	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS9687515
IDOV_5901	Virus nameVaccinia virus	Virus strainVVTK-FCU1	Virus genome typeDNA	Virus familyPoxviridae	Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in I4L gene	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with 5FU (100mg/kg)	Immune gene insertion in viral genomeNo	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismSwiss nude mice xenograft for U87MG(5.0E+6)	In-vivo virus concentration1.0E+7 pfu	In-vivo toxicityNA	In-vivo resultTumor volume reduced to below 500mm comapred to control 3500mm after 60 days	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS9687515