Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 14. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3105Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineLoVoNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 500mm after 50 daysIntravenousNANANA31011628
OV_3106Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineLoVoNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to 500mm after 50 daysIntravenousNANANA31011628
OV_3107Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoECACCHuman colon cancer cell lineOE19NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628
OV_3108Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoECACCHuman colon cancer cell lineOE19NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to 250 mm after 50 daysIntravenousNANANA31011628
OV_3109Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman bladder cancer cell lineSW780NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3110Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman bladder cancer cell lineSW780NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3111Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman hepatocellular carcinoma cell lineHepG2NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1500 mm after 50 daysIntravenousNANANA31011628
OV_3112Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman hepatocellular carcinoma cell lineHepG2NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628
OV_3113Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman stomach cancer cell lineHs746TNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 3500 mm after 50 daysIntravenousNANANA31011628
OV_3114Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman stomach cancer cell lineHs746TNANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 1000 mm after 50 daysIntravenousNANANA31011628
OV_3115Vaccinia virusDeltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL33NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3116Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoCantren Antoine- lacassagne, FranceHuman head and neck squamous cell carcinoma cell lineCAL33NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628
OV_3117Vaccinia virusVaccinia virus deltaJ2R/FCU1 VACVDNAPoxviridaeDeletion of J2R gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineHCT-116NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 500 mm after 50 daysIntravenousNANANA31011628
OV_3118Vaccinia virusDeltaJ2R-I4L/FCU1 VACV (TG6002)DNAPoxviridaeDeletion of J2R and I4L gene and insertion of gene FCU1NoVirus strain in combination with 5-FC (200mg/kg)NoATCCHuman colon cancer cell lineHCT-116NANANANANABD62 mice xenograft for Lovo cell line1.0E+7 pfuNA Tumor volume decreases to below 100 mm after 50 daysIntravenousNANANA31011628