Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 28. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_943	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_944	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_945	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	70% cancer cell survival after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_946	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_975	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 virus particle/cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_976	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_977	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	50% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_978	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	20% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1055	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1056	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 pfu/cell	80% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1057	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 pfu/cell	75% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1058	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 pfu/cell	30% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1059	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1060	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 pfu/cell	20% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1061	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 pfu/cell	20% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1062	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell killing after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1063	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survival after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1064	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell killing after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1065	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell killing after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1066	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell killing after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1067	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survival after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1068	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1069	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1070	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SKNBE	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_2891	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SKNBE2	5.0E+3 cells per well	NA	MTT assay	0.01 MOI	50% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2892	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SKNBE2	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2893	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SKNBE2	5.0E+3 cells per well	NA	MTT assay	1 MOI	38% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2894	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Neuroblastoma cell line	SKNBE2	5.0E+3 cells per well	NA	MTT assay	10 MOI	20% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608