| Primary information |
|---|
| OV_ID | OV_1065 |
| Virus Name | Herpes simplex virus |
| Strain | HSV-1 |
| Virus type | DNA |
| Virus family | Herpesviridae |
| Modification in virus genome | Mutant NV1066 |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | MediGene Inc. San Diego, CA |
| Origin of cell line | Neuroblastoma cell line |
| Cell line | SKNBE |
| Concentration of cell line | 4 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | 1000 pfu/cell |
| In-vitro result | 100% cell killing after 6 days |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Apoptosis induction and cspase 3 activation |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 15570577 |