Detailed description page of Selected OV_ID


OV_1064 details
Primary information
OV_IDOV_1064
Virus Name Herpes simplex virus
StrainHSV-1
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeMutant NV1066
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineMediGene Inc. San Diego, CA
Origin of cell lineNeuroblastoma cell line
Cell lineSKNBE
Concentration of cell line4
In-vitro toxicityNA
AssayNA
In-vitro virus concentration100 pfu/cell
In-vitro result100% cell killing after 6 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionApoptosis induction and cspase 3 activation
Immunogenic effectNA
Clinical trialNA
PMID15570577