The total number of records retrieved from this search are 14. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2606	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	5% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2607	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	10% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2608	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2609	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	1 MOI	30% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2610	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	40% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2611	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	50% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2612	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	60% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2613	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	10 MOI	70% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2614	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	50% cell growth suppression after day 1	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2615	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	70% cell growth suppression after day 2	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2616	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cell growth suppression after day 3	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2617	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cell growth suppression after day 4	No	No	NA	No response	NA	Induction of apoptosis in cancer	NA	NA	22842823
OV_2630	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SGC7901 (1.0E+6 cells)	1.0E+9 pfu	NA	Complete regression in tumor after 9 weeks and increase in median survival time upto 55 days	Intratumoral	Induction of apoptosis in cancer	NA	NA	22842823
OV_2631	Adenovirus	Ad-hTERT-E1a-Apoptin	DNA	Adenoviridae	Addition of E1a and apoptin before hTERT promoter	Yes	No	No	Type culture collection of chines academy, shanghai	Human gastric cancer cell line	SGC-7901	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SGC7901 (1.0E+6 cells)	1.0E+9 pfu	NA	Significant reduction in tumor volume and increase in median survival time ipto 345 days	Intravenous	Induction of apoptosis in cancer	NA	NA	22842823