Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 11. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2809AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (4 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-81 MOI20% cells viabilityNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2810AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (8 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-82 MOI18% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2811AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (16 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-4682000 cells per wellNACell counting kit-84 MOI10% cells are viableNoNoNA No responseNAMitotic arrest and induction of apoptosisNANA23525624
OV_2812AdenovirusG47-deltaDNAAdenoviridaeNoneNoVirus strain in combination with palcitaxel (16 nm)NoSun-sen university cancer centre, chinaHuman breast cancer cell lineMDA-MB-468NANANANANABALB/c nude mice xenograft for MDA-MB-468 (5.0E+6 cells)2.0E+5 pfuNA Reduction in tumor volume after 35 daysIntratumoralMitotic arrest and induction of apoptosisNANA23525624
OV_4292AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman breast carcinomaMDA-MB-4684000 cells per wellNAMTT assay10 pfu43.7 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_5554ReovirusReovirus serotype 3RNAReoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMDA-MB-46860% confluencyNANA40 MOICell viability drops to 12.7% after 24 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS6994858
OV_5555ReovirusReovirus serotype 3RNAReoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMDA-MB-46860% confluencyNANA40 MOICell viability drops to 8.8% after 48 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS6994858
OV_5556ReovirusReovirus serotype 3RNAReoviridaeNoneYesNoNoATCCHuman breast cancer cell lineMDA-MB-46860% confluencyNANA40 MOICell viability drops to 3.6% after 72 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS6994858
OV_5588ReovirusReovirus strain T3DRNAReoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineMDA-MB-468NANANANANASCID mice xenograft for MDA-MB468 (1.0E+5)1.0E+7 pfuNA Reduction in tumor volume to 38.33gm compared to control 128.54 after 4 weeksIntratumoralNANANAUS7374752
OV_5606Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineMDA-MB-46880% confluencyNAMTT assay44 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5825Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineMDA-MB-46880% confluencyNANA44 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578