Detailed description page of Selected OV_ID


OV_5588 details
Primary information
OV_IDOV_5588
Virus Name Reovirus
StrainReovirus strain T3D
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineHuman breast carcinoma cell line
Cell lineMDA-MB-468
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismSCID mice xenograft for MDA-MB468 (1 ×10⁵)
In-vivo virus concentration1 ×10⁷ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor volume to 38.33gm compared to control 128.54 after 4 weeks
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS7374752