Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 63. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_856AdenovirusCV890DNAAdenoviridaeE1A and E1B gene under control of Adenovirus promoterNoVirus strain in combination with Doxorubicin (10ng/ml)NoATCCHuman hepatoma cell lineHep3BNANAMTT assay0.01pfu/cell90% cancer cell killing after day 9, showing synergism with drugNoNoNA No responseNANANANA11522637
OV_857AdenovirusCV890DNAAdenoviridaeE1A and E1B gene under control of Adenovirus promoterYesNoNoATCCHuman hepatoma cell lineHep3BNANAMTT assay0.01pfu/cell35% cancer cell killing after day 9NoNoNA No responseNANANANA11522637
OV_885Herpes simplex virusMutantDNAHerpesviridaeDeletion mutant for Gamma 34.5YesNoNoATCCHepatocellular carcinoma cell lineHep3B3.0E+4 cells per wellNATrypan blue staining and hematocytometer0.1 pfu/ml75% cncer cell killing after 24 hoursNoNoNA No responseNANANANA12788648
OV_888Herpes simplex virusMutantDNAHerpesviridaeDeletion mutant for Gamma 34.5YesNoNoATCCHepatocellular carcinoma cell lineHep3B3.0E+4 cells per wellNATrypan blue staining and hematocytometer0.1 pfu/ml95% cncer cell killing after 48 hoursNoNoNA No responseNANANANA12788648
OV_891Herpes simplex virusMutantDNAHerpesviridaeDeletion mutant for Gamma 34.5YesNoNoATCCHepatocellular carcinoma cell lineHep3B3.0E+4 cells per wellNATrypan blue staining and hematocytometer0.01 pfu/ml70% cncer cell killing after 24 hoursNoNoNA No responseNANANANA12788648
OV_894Herpes simplex virusMutantDNAHerpesviridaeDeletion mutant for Gamma 34.5YesNoNoATCCHepatocellular carcinoma cell lineHep3B3.0E+4 cells per wellNATrypan blue staining and hematocytometer0.01 pfu/ml99% cncer cell killing after 48 hoursNoNoNA No responseNANANANA12788648
OV_1315AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining0.01 MOIsome cells are viableNoNoNA No responseNANANANA18281783
OV_1316AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining0.1 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1317AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining1 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1318AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining10 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1319AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining100 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1320AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining0.01 MOIsome cells are viableNoNoNA No responseNANANANA18281783
OV_1321AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining0.1 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1322AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining1 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1323AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining10 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1324AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining100 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1325AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining0.01 MOIsome cells are viableNoNoNA No responseNANANANA18281783
OV_1326AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining0.1 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1327AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining1 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1328AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining10 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1329AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANACrystal violet staining100 MOI100% cancer cell killingNoNoNA No responseNANANANA18281783
OV_1360AdenovirusCNHK300DNAAdenoviridaeNoneYesNoNoATCCHepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNAMTT assay0.01 MOI100% cell survivalNoNoNA No responseNANANANA18300357
OV_1361AdenovirusCNHK300DNAAdenoviridaeNoneYesNoNoATCCHepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNAMTT assay0.1 MOI30% cell survivalNoNoNA No responseNANANANA18300357
OV_1362AdenovirusCNHK300DNAAdenoviridaeNoneYesNoNoATCCHepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNAMTT assay1 MOI100% cell killingNoNoNA No responseNANANANA18300357
OV_1363AdenovirusCNHK300DNAAdenoviridaeNoneYesNoNoATCCHepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNAMTT assay10 MOI100% cell killingNoNoNA No responseNANANANA18300357
OV_1364AdenovirusCNHK300DNAAdenoviridaeNoneYesNoNoATCCHepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNAMTT assay100 MOI100% cell killingNoNoNA No responseNANANANA18300357
OV_1365AdenovirusCNHK300DNAAdenoviridaeNoneYesNoNoATCCHepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNAMTT assay1000 MOI100% cell killingNoNoNA No responseNANANANA18300357
OV_1920AdenovirusSG600-IL24DNAAdenoviridaeAddition of gene encoding IL24YesNoVirus expressing IL-24 geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI80% cell viability after 24 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_1921AdenovirusSG600-IL24DNAAdenoviridaeAddition of gene encoding IL24YesNoVirus expressing IL-24 geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI70% cell viability after 48 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_1922AdenovirusSG600-IL24DNAAdenoviridaeAddition of gene encoding IL24YesNoVirus expressing IL-24 geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI30% cell viability after 72 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_1923AdenovirusSG600-IL24DNAAdenoviridaeAddition of gene encoding IL24YesNoVirus expressing IL-24 geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI20% cell viability after 96 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_1932AdenovirusSG600-EGFPDNAAdenoviridaeAddition of gene encoding EGFPYesNoVirus expressing EGFP geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI90% cell viabilty after 24 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_1933AdenovirusSG600-EGFPDNAAdenoviridaeAddition of gene encoding EGFPYesNoVirus expressing EGFP geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI70% cell viability after 48 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_1934AdenovirusSG600-EGFPDNAAdenoviridaeAddition of gene encoding EGFPYesNoVirus expressing EGFP geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI70% cell viability after 72 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_1935AdenovirusSG600-EGFPDNAAdenoviridaeAddition of gene encoding EGFPYesNoVirus expressing EGFP geneInstitute of HCC, Fudan universityHuman liver cancer cell lineHep3B1.0E+3 cells per wellNAMTT assay10 MOI65% cell viability after 96 hoursNoNoNA No responseNAVirus induce the apoptosis in HCC cell lineNANA20872968
OV_2531AdenovirusAD55-ApoptinDNAAdenoviridaeDeletion of E1B gene and insertion of Apoptin geneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay0.1 MOI100% cells are viableNoNoNA No responseNAInduction of apotosis as measured by TUNEL assayNANA22321574
OV_2532AdenovirusAD55-ApoptinDNAAdenoviridaeDeletion of E1B gene and insertion of Apoptin geneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay1 MOI90% cells are viableNoNoNA No responseNAInduction of apotosis as measured by TUNEL assayNANA22321574
OV_2533AdenovirusAD55-ApoptinDNAAdenoviridaeDeletion of E1B gene and insertion of Apoptin geneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay10 MOI60% cellsa are viableNoNoNA No responseNAInduction of apotosis as measured by TUNEL assayNANA22321574
OV_2541AdenovirusAD55-ApoptinDNAAdenoviridaeDeletion of E1B gene and insertion of Apoptin geneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay10 MOI90% cells viable after day 1NoNoNA No responseNAInduction of apotosis as measured by TUNEL assayNANA22321574
OV_2542AdenovirusAD55-ApoptinDNAAdenoviridaeDeletion of E1B gene and insertion of Apoptin geneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay10 MOI80% cells viable after day 2NoNoNA No responseNAInduction of apotosis as measured by TUNEL assayNANA22321574
OV_2543AdenovirusAD55-ApoptinDNAAdenoviridaeDeletion of E1B gene and insertion of Apoptin geneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay10 MOI70% cells viable after day 3NoNoNA No responseNAInduction of apotosis as measured by TUNEL assayNANA22321574
OV_2544AdenovirusAD55-ApoptinDNAAdenoviridaeDeletion of E1B gene and insertion of Apoptin geneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay10 MOI60% cells viable after day 4NoNoNA No responseNAInduction of apotosis as measured by TUNEL assayNANA22321574
OV_2592AdenovirusAd.enAFP-E1A-delta-E1B-IL-24DNAAdenoviridaeDeletion of E1A, E1B and addition of AFP and IL-24YesNoVirus expressing IL-24 geneATCCHuman liver cancer cell lineHep3B5.0E+4 cells per wellNAMTT assay10 MOI10% cells are viable after 4 daysNoNoNA No responseNAInduction of apoptosis in cancerUpregulation of GADD34NA22790965
OV_2593AdenovirusAd.enAFP-E1A-delta-E1B-IL-24DNAAdenoviridaeDeletion of E1A, E1B and addition of AFP and IL-24YesNoVirus expressing IL-24 geneATCCHuman liver cancer cell lineHep3B5.0E+4 cells per wellNACrystal violet staining0.1 MOI100% cells viavilityNoNoNA No responseNAInduction of apoptosis in cancerUpregulation of GADD34NA22790965
OV_2594AdenovirusAd.enAFP-E1A-delta-E1B-IL-24DNAAdenoviridaeDeletion of E1A, E1B and addition of AFP and IL-24YesNoVirus expressing IL-24 geneATCCHuman liver cancer cell lineHep3B5.0E+4 cells per wellNACrystal violet staining1 MOISome cells are viableNoNoNA No responseNAInduction of apoptosis in cancerUpregulation of GADD34NA22790965
OV_2595AdenovirusAd.enAFP-E1A-delta-E1B-IL-24DNAAdenoviridaeDeletion of E1A, E1B and addition of AFP and IL-24YesNoVirus expressing IL-24 geneATCCHuman liver cancer cell lineHep3B5.0E+4 cells per wellNACrystal violet staining10 MOI100% cell deathNoNoNA No responseNAInduction of apoptosis in cancerUpregulation of GADD34NA22790965
OV_2596AdenovirusAd.enAFP-E1A-delta-E1B-IL-24DNAAdenoviridaeDeletion of E1A, E1B and addition of AFP and IL-24YesNoVirus expressing IL-24 geneATCCHuman liver cancer cell lineHep3B5.0E+4 cells per wellNACrystal violet staining100 MOI100% cell deathNoNoNA No responseNAInduction of apoptosis in cancerUpregulation of GADD34NA22790965
OV_2694AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneATCCHuman hepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNASpectrophotometer10 MOI80% cell viability after 24 hoursNoNoNA No responseNANANANA23028626
OV_2695AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneATCCHuman hepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNASpectrophotometer10 MOI60% cell viability after 48 hoursNoNoNA No responseNANANANA23028626
OV_2696AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneATCCHuman hepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNASpectrophotometer10 MOI40% cell viability after 72 hoursNoNoNA No responseNANANANA23028626
OV_2697AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneATCCHuman hepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNASpectrophotometer10 MOI40% cell viability after 96 hoursNoNoNA No responseNANANANA23028626
OV_2705AdenovirusAdCN205-IL12DNAAdenoviridaeNoneNoVirus in combination with CIKVirus expressing IL-12 geneATCCHuman hepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNASpectrophotometer10 MOI90% cell viability after 24 hoursNoNoNA No responseNANANANA23028626
OV_2706AdenovirusAdCN205-IL12DNAAdenoviridaeNoneNoVirus in combination with CIKVirus expressing IL-12 geneATCCHuman hepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNASpectrophotometer10 MOI80% cell viability after 48 hoursNoNoNA No responseNANANANA23028626
OV_2707AdenovirusAdCN205-IL12DNAAdenoviridaeNoneNoVirus in combination with CIKVirus expressing IL-12 geneATCCHuman hepatocellular carcinoma cell lineHep3B1.0E+4 cells per wellNASpectrophotometer10 MOI10% cell viability after 72 hoursNoNoNA No responseNANANANA23028626
OV_4276AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3B4000 cells per wellNAMTT assay10 pfu3.8 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4425Vesicular stomatitis virusRdBRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, no addition of linkerYesNoNoATCCHuman liver cancer cell lineHep3B1.2E+4 cells per wellNAMTT assay21:1 particle to pfu70% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4433Vesicular stomatitis virusRdB-1L-VSVGRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, addition of single linkerYesNoNoATCCHuman liver cancer cell lineHep3B1.2E+4 cells per wellNAMTT assay24:1 particle to pfu30% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4877AdenovirusAd-deltaBDNAAdenoviridaeNoneYesNoNoATCCHuman hepatocellular carcinomaHep3B70% confluence on 24 well plateNAMTT assay5 MOI100% cell viability after 48 hoursNoNoNA No responseNACombination therapy and alone promotes apoptosisActivation of caspase-3 and 8 and upregulation of IFN-gammaNA27154307
OV_4878AdenovirusAd-deltaBDNAAdenoviridaeNoneYesNoNoATCCHuman hepatocellular carcinomaHep3B70% confluence on 24 well plateNAMTT assay10 MOI90% cell viability after 48 hoursNoNoNA No responseNACombination therapy and alone promotes apoptosisActivation of caspase-3 and 8 and upregulation of IFN-gammaNA27154307
OV_4879AdenovirusAd-deltaBDNAAdenoviridaeExpressing TRAIL and IL-12 gene in under CMV promoter in deleted E3 region of virus backboneYesNoVirus expressing IL12 geneATCCHuman hepatocellular carcinomaHep3B70% confluence on 24 well plateNAMTT assay10 MOI50% cell viability after 48 hoursNoNoNA No responseNACombination therapy and alone promotes apoptosisActivation of caspase-3 and 8 and upregulation of IFN-gammaNA27154307
OV_4880AdenovirusAd-deltaBDNAAdenoviridaeExpressing TRAIL and IL-12 gene in under CMV promoter in deleted E3 region of virus backboneYesNoVirus expressing IL12 geneATCCHuman hepatocellular carcinomaHep3B70% confluence on 24 well plateNAMTT assay20 MOI40% cell viability after 48 hoursNoNoNA No responseNACombination therapy and alone promotes apoptosisActivation of caspase-3 and 8 and upregulation of IFN-gammaNA27154307
OV_5669AdenovirusOV802DNAAdenoviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay0.01 MOIComplete cancer cell deathNoNoNA No responseNANAInduction of IFN-Gamma, IL6 and other immunostimulatory cytokines productionNAUS7473418
OV_5670AdenovirusOV802DNAAdenoviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell lineHep3BNANAMTT assay1 MOIComplete cancer cell death after day 5NoNoNA No responseNANAInduction of IFN-Gamma, IL6 and other immunostimulatory cytokines productionNAUS7473418