The total number of records retrieved from this search are 46. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_325	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	2.5E+4 cells per well	NA	Crystal violet staining	1 MOI	98% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_329	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	2.5E+4 cells per well	NA	Crystal violet staining	2.5 MOI	98% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_333	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	2.5E+4 cells per well	NA	Crystal violet staining	5 MOI	98% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_337	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	2.5E+4 cells per well	NA	Crystal violet staining	10 MOI	99% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_341	Adenovirus	Adhz60	DNA	Adenoviridae	E1b-deleted mutant	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	2.5E+4 cells per well	NA	Crystal violet staining	20 MOI	100% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	26561948
OV_2785	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	Crystal violet staining	0.1 MOI	No cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2786	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	Crystal violet staining	0.5 MOI	No cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2787	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	Crystal violet staining	1 MOI	No cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2788	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	Crystal violet staining	5 MOI	Moderate cell death	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2789	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	Crystal violet staining	10 MOI	All cell was dead	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2790	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	MTT assay	0.5 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2791	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	MTT assay	1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2792	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	MTT assay	2 MOI	80% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2793	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	MTT assay	5 MOI	80% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_2794	Adenovirus	Ad.sp-E1A-TSLC1	DNA	Adenoviridae	Deletion of 24bp with in E1A gene and insertion of TSLC1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	NA	NA	MTT assay	10 MOI	60% cells are viable	No	No	NA	No response	NA	Induction of apotosis by virus in cancer cell line as measured by TUNEL assay	NA	NA	23503473
OV_3332	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	10 pfu	100% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3333	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	100 pfu	70% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3334	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	1000 pfu	60% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3335	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	10 pfu	80% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3336	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	100 pfu	30% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3337	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	1000 pfu	20% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3338	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	10 pfu	70% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3339	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	100 pfu	20% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3340	Reovirus	Recombinant reovirus T1L	RNA	Reoviridae	Mutant in L1 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	1000 pfu	100% cell killing after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3341	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	10 pfu	100% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3342	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	100 pfu	90% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3343	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	1000 pfu	80% cell viability after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3344	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	10 pfu	100% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3345	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	100 pfu	80% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3346	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	1000 pfu	70% cell viability after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3347	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	10 pfu	100% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3348	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	100 pfu	90% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3349	Reovirus	Recombinant reovirus T3L	RNA	Reoviridae	Substitution mutant in T3 gene	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	1.0E+4 cells per well	NA	Cell-titer-glo assay	1000 pfu	70% cell viability after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	28587298
OV_3631	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	5000 cells per well	NA	MTT assay	1 MOI	30% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3632	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	5000 cells per well	NA	MTT assay	1 MOI	5% cell viability after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3645	Mumps virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	5000 cells per well	NA	MTT assay	1 MOI	80% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3646	Mumps virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human lung cancer cell line	H-1299	5000 cells per well	NA	MTT assay	1 MOI	20% cell viability after day 6	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3659	Measles and mumps virus	wild type	RNA	Paramyxoviridae	None	No	Measles virus in combination with mumps virus	No	ATCC	Human lung cancer cell line	H-1299	5000 cells per well	NA	MTT assay	1 MOI	70% cell viability after day 3	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_3660	Measles and mumps virus	wild type	RNA	Paramyxoviridae	None	No	Measles virus in combination with mumps virus	No	ATCC	Human lung cancer cell line	H-1299	5000 cells per well	NA	MTT assay	1 MOI	Complete cell death after 6 days	No	No	NA	No response	NA	Virus in combination with induce apiptosis in cancer cell	NA	NA	29485292
OV_4326	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human nonsmall cell lung cancer	H-1299	4000 cells per well	NA	MTT assay	10 pfu	96.3 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_4947	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	10 MOI	20% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4948	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	1 MOI	30% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4949	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	0.1 MOI	50% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4950	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	0.01 MOI	70% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_5596	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human lung carcinoma cell line	H-1299	80% confluency	NA	MTT assay	26 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5832	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human lung adenocarcinoma cell line	H-1299	80% confluency	NA	NA	26 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578