The total number of records retrieved from this search are 8. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3066	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	18% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3067	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	1% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3068	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3096	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	18% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3097	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	2% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3098	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3115	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 100 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_3116	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	Cantren Antoine- lacassagne, France	Human head and neck squamous cell carcinoma cell line	CAL33	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 100 mm after 50 days	Intravenous	NA	NA	NA	31011628