The total number of records retrieved from this search are 20. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_608	Adenovirus	CRAd-CCL21-IL15	DNA	Adenoviridae	Insertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells	Yes	No	IL-15	ATCC	Human bone osteosarcoma epithelial cell line	U2OS (telomerase-negative)	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	96% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	27380620
OV_611	Adenovirus	CRAd-CCL21-IL15	DNA	Adenoviridae	Insertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells	Yes	No	IL-15	ATCC	Human bone osteosarcoma epithelial cell line	U2OS (telomerase-negative)	1.0E+5 cells per well	NA	MTT assay	1 MOI	94% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	27380620
OV_614	Adenovirus	CRAd-CCL21-IL15	DNA	Adenoviridae	Insertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells	Yes	No	IL-15	ATCC	Human bone osteosarcoma epithelial cell line	U2OS (telomerase-negative)	1.0E+5 cells per well	NA	MTT assay	10 MOI	92% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	27380620
OV_617	Adenovirus	CRAd-CCL21-IL15	DNA	Adenoviridae	Insertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells	Yes	No	IL-15	ATCC	Human bone osteosarcoma epithelial cell line	U2OS (telomerase-negative)	1.0E+5 cells per well	NA	MTT assay	50 MOI	90% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	27380620
OV_4112	Adenovirus	Ad-CCL20-CD40L	DNA	Adenoviridae	Addition of CCL20 and CD40L gene near by TERT promoter	Yes	No	virus expressing CCL20 chemokine gene	ATCC	Human osteosarcoma cell line	U2OS	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	95% cell survival after 7 days	No	No	NA	No response	NA	NA	NA	NA	26208317
OV_4116	Adenovirus	Ad-CCL20-CD40L	DNA	Adenoviridae	Addition of CCL20 and CD40L gene near by TERT promoter	Yes	No	virus expressing CCL20 chemokine gene	ATCC	Human osteosarcoma cell line	U2OS	1.0E+5 cells per well	NA	MTT assay	1 MOI	90% cell survival after 7 days	No	No	NA	No response	NA	NA	NA	NA	26208317
OV_4120	Adenovirus	Ad-CCL20-CD40L	DNA	Adenoviridae	Addition of CCL20 and CD40L gene near by TERT promoter	Yes	No	virus expressing CCL20 chemokine gene	ATCC	Human osteosarcoma cell line	U2OS	1.0E+5 cells per well	NA	MTT assay	10 MOI	90% cell survival after 7 days	No	No	NA	No response	NA	NA	NA	NA	26208317
OV_4124	Adenovirus	Ad-CCL20-CD40L	DNA	Adenoviridae	Addition of CCL20 and CD40L gene near by TERT promoter	Yes	No	virus expressing CCL20 chemokine gene	ATCC	Human osteosarcoma cell line	U2OS	1.0E+5 cells per well	NA	MTT assay	100 MOI	95% cell survival after 7 days	No	No	NA	No response	NA	NA	NA	NA	26208317
OV_4933	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	0.1 MOI	100% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4934	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	1 MOI	100% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4935	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	10 MOI	100% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4936	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	50 MOI	100% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4937	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 gene in virus genome	Yes	No	Virus expressing IL-21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	0.1 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4938	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 gene in virus genome	Yes	No	Virus expressing IL-21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	1 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4939	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 gene in virus genome	Yes	No	Virus expressing IL-21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	10 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4940	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 gene in virus genome	Yes	No	Virus expressing IL-21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	50 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4941	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 and CCL21gene in virus genome	Yes	No	Virus expressing IL-21 and CCL21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	0.1 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4942	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 and CCL21gene in virus genome	Yes	No	Virus expressing IL-21 and CCL21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	1 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4943	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 and CCL21gene in virus genome	Yes	No	Virus expressing IL-21 and CCL21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	10 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859
OV_4944	Adenovirus	wild type	DNA	Adenoviridae	Addition of IL21 and CCL21gene in virus genome	Yes	No	Virus expressing IL-21 and CCL21 gene	ATCC	Human osteosarcoma cell line	U2OS	1 million cells per well	NA	MTT assay	50 MOI	90% cell viability after 7 days	No	No	NA	No response	NA	NA	Activate proloferation of B-cell and Naive T-cell	NA	27157859