Detailed description page of Selected OV_ID


OV_614 details
Primary information
OV_IDOV_614
Virus Name Adenovirus
StrainCRAd-CCL21-IL15
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cells
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeIL-15
Source of cell lineATCC
Origin of cell lineHuman bone osteosarcoma epithelial cell line
Cell lineU2OS (telomerase-negative)
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result92% cancer cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27380620