Primary information |
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OV_ID | OV_4124 |
Virus Name | Adenovirus |
Strain | Ad-CCL20-CD40L |
Virus type | DNA |
Virus family | Adenoviridae |
Modification in virus genome | Addition of CCL20 and CD40L gene near by TERT promoter |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | virus expressing CCL20 chemokine gene |
Source of cell line | ATCC |
Origin of cell line | Human osteosarcoma cell line |
Cell line | U2OS |
Concentration of cell line | 1 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 100 MOI |
In-vitro result | 95% cell survival after 7 days |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 26208317 |