The total number of records retrieved from this search are 14. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_2606	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro result5% cell growth suppression after day 1	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2607	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro result10% cell growth suppression after day 2	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2608	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro result20% cell growth suppression after day 3	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2609	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro result30% cell growth suppression after day 4	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2610	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result40% cell growth suppression after day 1	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2611	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result50% cell growth suppression after day 2	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2612	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result60% cell growth suppression after day 3	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2613	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result70% cell growth suppression after day 4	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2614	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration100 MOI	In-vitro result50% cell growth suppression after day 1	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2615	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration100 MOI	In-vitro result70% cell growth suppression after day 2	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2616	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration100 MOI	In-vitro result100% cell growth suppression after day 3	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2617	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration100 MOI	In-vitro result100% cell growth suppression after day 4	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2630	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismBALB/c nude mice xenograft for SGC7901 (1.0E+6 cells)	In-vivo virus concentration1.0E+9 pfu	In-vivo toxicityNA	In-vivo resultComplete regression in tumor after 9 weeks and increase in median survival time upto 55 days	Mode of deliveryIntratumoral	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823
IDOV_2631	Virus nameAdenovirus	Virus strainAd-hTERT-E1a-Apoptin	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of E1a and apoptin before hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineType culture collection of chines academy, shanghai	Origin of cell lineHuman gastric cancer cell line	Cell lineSGC-7901	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismBALB/c nude mice xenograft for SGC7901 (1.0E+6 cells)	In-vivo virus concentration1.0E+9 pfu	In-vivo toxicityNA	In-vivo resultSignificant reduction in tumor volume and increase in median survival time ipto 345 days	Mode of deliveryIntravenous	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectNA	Clinical trialNA	PMID22842823