The total number of records retrieved from this search are 12. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1246	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	Yes	No	VSV in combination with cisplatin (0.1 microgram/ml)	Virus expressing IL-12 gene	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	No cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1247	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	Yes	No	VSV in combination with cisplatin (0.1 microgram/ml)	Virus expressing IL-12 gene	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	80% cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1248	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	Yes	No	VSV in combination with cisplatin (0.1 microgram/ml)	Virus expressing IL-12 gene	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1249	Vesicular stomatitis virus	Fusogenic strain	RNA	Rhabdoviridae	Yes , expressing fusion protein	No	VSV in combination with cisplatin (0.1 microgram/ml)	No	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	10% cancer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1250	Vesicular stomatitis virus	Fusogenic strain	RNA	Rhabdoviridae	Yes , expressing fusion protein	No	VSV in combination with cisplatin (0.1 microgram/ml)	No	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cancer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1251	Vesicular stomatitis virus	Fusogenic strain	RNA	Rhabdoviridae	Yes , expressing fusion protein	No	VSV in combination with cisplatin (0.1 microgram/ml)	No	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_4483	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	10 MOI	70% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4484	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	10 MOI	60% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4485	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	10 MOI	50% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4486	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	100 MOI	50% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4487	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	100 MOI	40% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4488	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	100 MOI	30% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291