Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 36. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_606AdenovirusCRAd-CCL21-IL15DNAAdenoviridaeInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cellsYesNoIL-15Key Laboratory of Zoonosis, Jilin UniversityHuman prostate cancer cell linePC-3M1.0E+5 cells per wellNAMTT assay0.1 MOI70% cancer cell viabilityNoNoNA No responseNANANANA27380620
OV_609AdenovirusCRAd-CCL21-IL15DNAAdenoviridaeInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cellsYesNoIL-15Key Laboratory of Zoonosis, Jilin UniversityHuman prostate cancer cell linePC-3M1.0E+5 cells per wellNAMTT assay1 MOI40% cancer cell viabilityNoNoNA No responseNANANANA27380620
OV_612AdenovirusCRAd-CCL21-IL15DNAAdenoviridaeInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cellsYesNoIL-15Key Laboratory of Zoonosis, Jilin UniversityHuman prostate cancer cell linePC-3M1.0E+5 cells per wellNAMTT assay10 MOI18% cancer cell viabilityNoNoNA No responseNANANANA27380620
OV_615AdenovirusCRAd-CCL21-IL15DNAAdenoviridaeInsertion mutant for CCL21 and IL15 genes with TERTp to target the TERT-positive cancer cellsYesNoIL-15Key Laboratory of Zoonosis, Jilin UniversityHuman prostate cancer cell linePC-3M1.0E+5 cells per wellNAMTT assay50 MOI10% cancer cell viabilityNoNoNA No responseNANANANA27380620
OV_898Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell2% cancer cell killing after 24 hourNoNoNA No responseNANANANA15129429
OV_899Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell20% cancer cell killing after 24 hourNoNoNA No responseNANANANA15129429
OV_900Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell50% cancer cell killing after 24 hourNoNoNA No responseNANANANA15129429
OV_901Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell20% cancer cell killing after 48 hourNoNoNA No responseNANANANA15129429
OV_902Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell40% cancer cell killing after 48 hourNoNoNA No responseNANANANA15129429
OV_903Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell80% cancer cell killing after 48 hourNoNoNA No responseNANANANA15129429
OV_904Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell60% cancer cell killing after 72 hoursNoNoNA No responseNANANANA15129429
OV_905Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell80% cancer cell killing after 72 hoursNoNoNA No responseNANANANA15129429
OV_906Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.01 pfu/cell90% cancer cell killing after 72 hoursNoNoNA No responseNANANANA15129429
OV_907Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell20% cancer cell killing after 24 hourNoNoNA No responseNANANANA15129429
OV_908Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell30% cancer cell killing after 24 hourNoNoNA No responseNANANANA15129429
OV_909Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell50% cancer cell killing after 24 hourNoNoNA No responseNANANANA15129429
OV_910Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell50% cancer cell killing after 48 hourNoNoNA No responseNANANANA15129429
OV_911Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell60% cancer cell killing after 48 hourNoNoNA No responseNANANANA15129429
OV_912Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell100% cancer cell killing after 48 hourNoNoNA No responseNANANANA15129429
OV_913Herpes simplex virusBaco-1DNAHerpesviridaeNon- fusogenic ligated with EGFP proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell60% cancer cell killing after 72 hoursNoNoNA No responseNANANANA15129429
OV_914Herpes simplex virusSynco-2DNAHerpesviridaeFusogenic membrane ligated with GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell80% cancer cell killing after 72 hoursNoNoNA No responseNANANANA15129429
OV_915Herpes simplex virusSynco-2DDNAHerpesviridaeDouble fusogenic expressing EGFP and GALV.fus proteinYesNoNoATCCProstate cancer cell linePC-3M-Pro45.0E+4 cells per wellNATrypan blue staining0.1 pfu/cell100% cancer cell killing after 72 hoursNoNoNA No responseNANANANA15129429
OV_3724Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell linePC-3M-LucNANAAbsorbance measurements0.1 MOI50% cell viableNoNoNA No responseVirus induce apoptosis in cancer cellNANANA29696636
OV_3731Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell linePC-3M-LucNANAAbsorbance measurements10 MOI18% cell viableNoNoNA No responseVirus induce apoptosis in cancer cellNANANA29696636
OV_4909Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay0.1 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4910Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay1 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4911Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay10 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4912Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay50 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4913Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay0.1 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4914Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay1 MOI90% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4915Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay10 MOI30% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4916Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay50 MOI15% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4917Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay0.1 MOI70% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4918Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay1 MOI40% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4919Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay10 MOI15% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4920Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay50 MOI15% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859