Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 28. Click on ID to see further detail.
IDOV_4509Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 VP/cellIn-vitro result100% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4510Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.001mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 VP/cellIn-vitro result75% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4511Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.0025mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 VP/cellIn-vitro result75% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4512Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.005mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 VP/cellIn-vitro result62% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4513Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 VP/cellIn-vitro result90% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4514Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.001mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 VP/cellIn-vitro result70% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4515Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.0025mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 VP/cellIn-vitro result70% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4516Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.005mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 VP/cellIn-vitro result70% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4517Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration100 VP/cellIn-vitro result40% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4518Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.001mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration100 VP/cellIn-vitro result35% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4519Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.0025mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration100 VP/cellIn-vitro result30% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4520Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.005mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration100 VP/cellIn-vitro result35% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4521Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1000 VP/cellIn-vitro result18% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4522Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.001mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1000 VP/cellIn-vitro result15% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4523Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.0025mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1000 VP/cellIn-vitro result15% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4524Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with 4-HP-CP (0.005mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1000 VP/cellIn-vitro result15% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4525Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 VP/cellIn-vitro result100% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4526Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.0075mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 VP/cellIn-vitro result90% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4527Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.05mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1 VP/cellIn-vitro result80% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4528Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 VP/cellIn-vitro result80% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4529Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.0075mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 VP/cellIn-vitro result70% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4530Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.05mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration10 VP/cellIn-vitro result62% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4531Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration100 VP/cellIn-vitro result40% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4532Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.0075mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration100 VP/cellIn-vitro result40% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4533Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.05mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration100 VP/cellIn-vitro result40% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4534Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1000 VP/cellIn-vitro result20% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4535Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.0075mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1000 VP/cellIn-vitro result20% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453
IDOV_4536Virus nameAdenovirusVirus strainAd5/3-D24-GMCSFVirus genome typeDNAVirus familyAdenoviridaeVirus genome modificationAd5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSFVirus aloneNoVirus in combination with drug/radiationVirus in combination with Cyclophosphamide (0.05mg/ml)Immune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer triple negative cell lineCell lineMDA-MB-436Concentration of cell line1000 cells per wellIn-vitro toxicityNAAssayMTS assayIn-vitro virus concentration1000 VP/cellIn-vitro result20% cancer cell survival after 5 daysModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectVirus induced tumor specific T-cell responseClinical trialNAPMID27057453