The total number of records retrieved from this search are 12. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1153	Herpes simplex virus	NV1020	DNA	Herpesviridae	None	Yes	No	No	ATCC	Colon carcinoma cell line	LS174T	5.0E+3 cells per well	NA	WST-1 assay	1 × 10⁶ pfu/ml	70% cell killing	No	No	NA	No response	NA	NA	NA	NA	17117895
OV_3144	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	5 MOI	50% cell viability	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3145	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	10 MOI	30% cell viability	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3146	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	20 MOI	25% cell viability	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3151	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	10 MOI	90% cell viability after day 1	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3152	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	10 MOI	80% cell viability after day 2	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3153	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	10 MOI	70% cell viability after day 3	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3154	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	10 MOI	40% cell viability after day 4	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3156	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	Yes	No	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	NA	NA	NA	NA	NA	Mouse model xenograft for LS174T (1.0E+6)	5.0E+8 pfu	NA	Reduction in tumor volume below 500mm as compared to control 3000mm after 24 days	Intratumoral	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3160	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	No	Virus in combination with rapamycin (5nM)	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	5 MOI	70% cell viability	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3161	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	No	Virus in combination with rapamycin (10nM)	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	10 MOI	50% cell viability	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127
OV_3162	Herpes simplex virus	SPDD-UG	DNA	Adenoviridae	Virus expressing SNORD44 gene and GAS5 gene	No	Virus in combination with rapamycin (20nM)	No	Cell bank of type culture collection of chinese academy of science	Human colon carcinoma cell line	LS174T	2000 cells per well	NA	CCK-8 assay	20 MOI	40% cell viability	No	No	NA	No response	NA	Caspase dependent Induction of apoptosis as measured by TUNEL assay in both tumor model and cell line	NA	NA	28530127