The total number of records retrieved from this search are 18. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_2677	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.01 MOI	In-vitro result100% cell survival after 24 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2678	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.01 MOI	In-vitro result100% cell survival after 48 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2679	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.01 MOI	In-vitro result90% cell survival after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2680	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.01 MOI	In-vitro result80% cell survival after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2681	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.1 MOI	In-vitro result100% cell survival after 24 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2682	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.1 MOI	In-vitro result90% cell survival after 48 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2683	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.1 MOI	In-vitro result90% cell survival after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2684	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration0.1 MOI	In-vitro result70% cell survival after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2685	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration1 MOI	In-vitro result100% cell survival after 24 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2686	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration1 MOI	In-vitro result80% cell survival after 48 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2687	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration1 MOI	In-vitro result70% cell survival after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_2688	Virus nameMeasles virus	Virus strainMV-Edm	Virus genome typeRNA	Virus familyParamyxoviridae	Virus genome modificationInsertion of human CEA gene upstream of MV N gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma cell line	Cell lineHuh-6	Concentration of cell line2.0E+5 cells per well	In-vitro toxicityNA	AssayCell proliferation assay kit	In-vitro virus concentration1 MOI	In-vitro result50% cell survival after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis in cancer	Immunogenic effectIncrease expression of CD46	Clinical trialNA	PMID23009685
IDOV_4302	Virus nameAlphavirus	Virus strainM1	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma	Cell lineHuh-6	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 pfu	In-vitro result59 % cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	Immunogenic effectNA	Clinical trialNA	PMID26373347
IDOV_4338	Virus nameAlphavirus	Virus strainM1	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma	Cell lineHuh-6	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration0.001 MOI	In-vitro result100% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	Immunogenic effectNA	Clinical trialNA	PMID26373347
IDOV_4339	Virus nameAlphavirus	Virus strainM1	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma	Cell lineHuh-6	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration0.01 MOI	In-vitro result98% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	Immunogenic effectNA	Clinical trialNA	PMID26373347
IDOV_4340	Virus nameAlphavirus	Virus strainM1	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma	Cell lineHuh-6	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration0.1 MOI	In-vitro result90% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	Immunogenic effectNA	Clinical trialNA	PMID26373347
IDOV_4341	Virus nameAlphavirus	Virus strainM1	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma	Cell lineHuh-6	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result78% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	Immunogenic effectNA	Clinical trialNA	PMID26373347
IDOV_4342	Virus nameAlphavirus	Virus strainM1	Virus genome typeRNA	Virus familyTogaviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman hepatoblastoma	Cell lineHuh-6	Concentration of cell line4000 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration100 MOI	In-vitro result62% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	Immunogenic effectNA	Clinical trialNA	PMID26373347