Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 34. Click on ID to see further detail.
IDOV_3386 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3387 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3388 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3389 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3390 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result55% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3391 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3392 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3393 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3394 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result40% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3395 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3396 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3397 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3398 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3399 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3400 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3401 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result80% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3402 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3403 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1975 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_4587 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4588 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4589 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4590 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4591 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cancer cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4592 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cancer cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4593 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result100% cancer cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4594 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result90% cancer cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4595 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result80% cancer cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4596 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result80% cancer cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4597 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result80% cancer cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4598 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cancer cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4599 | Virus nameAdenovirus | Virus strainCD55-TRAIL+ CD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIl and MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result80% cancer cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4600 | Virus nameAdenovirus | Virus strainCD55-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing MnSOD gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result80% cancer cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4601 | Virus nameAdenovirus | Virus strainCD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationvirus containing TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result80% cancer cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |
IDOV_4602 | Virus nameAdenovirus | Virus strainCD55-TRAIL-IETD-MnSOD | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung carcinoma cell line | Cell lineNCI-H1975 | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cancer cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27080225 |