Detailed description page of Selected OV_ID


OV_3388 details
Primary information
OV_IDOV_3388
Virus Name Reovirus
StrainRecombinant reovirus T1L
Virus typeRNA
Virus familyReoviridae
Modification in virus genomeMutant in L1 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman lung cancer cell line
Cell lineH1975
Concentration of cell line1
In-vitro toxicityNA
AssayCell-titer-glo assay
In-vitro virus concentration1000 pfu
In-vitro result70% cell viability after 24 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis
Immunogenic effectNA
Clinical trialNA
PMID28587298