Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 46. Click on ID to see further detail.
IDOV_325 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro result98% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_329 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration2.5 MOI | In-vitro result98% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_333 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration5 MOI | In-vitro result98% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_337 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro result99% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_341 | Virus nameAdenovirus | Virus strainAdhz60 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationE1b-deleted mutant | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line2.5E+4 cells per well | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration20 MOI | In-vitro result100% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26561948 |
IDOV_2785 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.1 MOI | In-vitro resultNo cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2786 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.5 MOI | In-vitro resultNo cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2787 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro resultNo cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2788 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration5 MOI | In-vitro resultModerate cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2789 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro resultAll cell was dead | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2790 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result90% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2791 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2792 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result80% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2793 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result80% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_2794 | Virus nameAdenovirus | Virus strainAd.sp-E1A-TSLC1 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDeletion of 24bp with in E1A gene and insertion of TSLC1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cells are viable | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apotosis by virus in cancer cell line as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID23503473 |
IDOV_3332 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result100% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3333 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3334 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result60% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3335 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3336 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result30% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3337 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result20% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3338 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3339 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result20% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3340 | Virus nameReovirus | Virus strainRecombinant reovirus T1L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationMutant in L1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result100% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3341 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result100% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3342 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3343 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result80% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3344 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result100% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3345 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3346 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3347 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration10 pfu | In-vitro result100% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3348 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration100 pfu | In-vitro result90% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3349 | Virus nameReovirus | Virus strainRecombinant reovirus T3L | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationSubstitution mutant in T3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayCell-titer-glo assay | In-vitro virus concentration1000 pfu | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID28587298 |
IDOV_3631 | Virus nameMeasles virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3632 | Virus nameMeasles virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result5% cell viability after day 6 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3645 | Virus nameMumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3646 | Virus nameMumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result20% cell viability after day 6 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3659 | Virus nameMeasles and mumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationMeasles virus in combination with mumps virus | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cell viability after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_3660 | Virus nameMeasles and mumps virus | Virus strainwild type | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationMeasles virus in combination with mumps virus | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro resultComplete cell death after 6 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29485292 |
IDOV_4326 | Virus nameAlphavirus | Virus strainM1 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman nonsmall cell lung cancer | Cell lineH-1299 | Concentration of cell line4000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 pfu | In-vitro result96.3 % cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis | Immunogenic effectNA | Clinical trialNA | PMID26373347 |
IDOV_4947 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4948 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4949 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4950 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_5596 | Virus nameNewcastle disease virus | Virus strainNDV-MK107 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung carcinoma cell line | Cell lineH-1299 | Concentration of cell line80% confluency | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration26 pfu | In-vitro result50% of cancer cell death occurs | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis by virus infection | Immunogenic effectInduction of IFN-Gamma production | Clinical trialNA | PMIDUS7470426 |
IDOV_5832 | Virus nameNewcastle disease virus | Virus strainNDV-PPMK107 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman lung adenocarcinoma cell line | Cell lineH-1299 | Concentration of cell line80% confluency | In-vitro toxicityNA | AssayNA | In-vitro virus concentration26 pfu | In-vitro result50% cancer cell death | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS8105578 |