The total number of records retrieved from this search are 28. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_360	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	CHLA-20	4000 cells per well	NA	MTS cell survival assay	0.0001 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_364	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	CHLA-20	4000 cells per well	NA	MTS cell survival assay	0.01 MOI	100% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_368	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	CHLA-20	4000 cells per well	NA	MTS cell survival assay	0.1 MOI	98% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_372	Herpes simplex virus	Seprehvir (HSV1716)	DNA	Herpesviridae	Δγ134.5 attenuated virus mutant	Yes	No	No	ATCC or from the Pediatric Preclinical Testing Program (PPTP)	Human neuroblastoma cell line	CHLA-20	4000 cells per well	NA	MTS cell survival assay	1 MOI	72% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26583803
OV_939	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 virus particle/cell	90% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_940	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	80% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_941	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_942	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	70% cancer cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_971	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 virus particle/cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_972	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_973	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_974	Adenovirus	wild type	DNA	Adenoviridae	None	Yes	No	No	Alabama-Birmingham	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 virus particle/ cell	70% cancer cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1039	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1040	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1041	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1042	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 pfu/cell	90% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1043	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 pfu/cell	80% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1044	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 pfu/cell	80% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1045	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 pfu/cell	80% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1046	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 pfu/cell	20% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1047	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 pfu/cell	90% cell survival after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1048	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 pfu/cell	60% cell survival after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1049	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 pfu/cell	20% cell survival after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1050	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell killing after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1051	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10 pfu/cell	10% cell survival after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1052	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	100 pfu/cell	10% cell survival after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1053	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	1000 pfu/cell	10% cell survival after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1054	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	CHLA-20	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell killing after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577