| Primary information |
|---|
| OV_ID | OV_360 |
| Virus Name | Herpes simplex virus |
| Strain | Seprehvir (HSV1716) |
| Virus type | DNA |
| Virus family | Herpesviridae |
| Modification in virus genome | Δγ134.5 attenuated virus mutant |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC or from the Pediatric Preclinical Testing Program (PPTP) |
| Origin of cell line | Human neuroblastoma cell line |
| Cell line | CHLA-20 |
| Concentration of cell line | 4000 |
| In-vitro toxicity | NA |
| Assay | MTS cell survival assay |
| In-vitro virus concentration | 0.0001 MOI |
| In-vitro result | 100% cancer cell viability |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 26583803 |