Detailed description page of Selected OV_ID


OV_372 details
Primary information
OV_IDOV_372
Virus Name Herpes simplex virus
StrainSeprehvir (HSV1716)
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeΔγ134.5 attenuated virus mutant
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC or from the Pediatric Preclinical Testing Program (PPTP)
Origin of cell lineHuman neuroblastoma cell line
Cell lineCHLA-20
Concentration of cell line4000
In-vitro toxicityNA
AssayMTS cell survival assay
In-vitro virus concentration1 MOI
In-vitro result72% cancer cell viability
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26583803