Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 36. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3735Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell lineLAPC4NANAAbsorbance measurements10 MOI10% cell viableNoNoNA No responseVirus induce apoptosis in cancer cellNANANA29696636
OV_3736Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell lineTRAMP-C1NANAAbsorbance measurements10 MOI5% cell viableNoNoNA No responseVirus induce apoptosis in cancer cellNANANA29696636
OV_3737Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell lineDu145NANANANANABalb/c-rag and gamma negative xenograft for Du145 (2.0E+6)1.0E+7 pfuNA Complete regression in tumor after day 80IntratumoralNANANA29696636
OV_3738Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell line22RV1NANANANANABalb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)1.0E+7 pfuNA Regression in tumor volume to 0.4 cm after day 80IntratumoralNANANA29696636
OV_3739Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell line22RV1NANANANANABalb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)1.0E+7 pfuNA Complete regression in tumor after day 80IntravenousNANANA29696636
OV_3740Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell lineVCaPNANANANANABalb/c-rag and gamma negative xenograft for VCap (2.0E+6)1.0E+7 pfuNA Regression in tumor volume to 0.3 cm after day 80IntratumoralNANANA29696636
OV_4086Vaccinia virusVVstrain LIVP 6.1.1DNAPoxviridaeMutant for J2R geneYesNoNoUniversity of veterinary medicine, germanyHuman prostate carcinoma cell lineCT1258NANAMTT assay0.1 MOI90% cell survival after 24 hoursNoNoNA No responseNANANANA26205404
OV_4090Vaccinia virusVVstrain LIVP 6.1.1DNAPoxviridaeMutant for J2R geneYesNoNoUniversity of veterinary medicine, germanyHuman prostate carcinoma cell lineCT1258NANAMTT assay0.1 MOI40% cell survival after 48 hoursNoNoNA No responseNANANANA26205404
OV_4094Vaccinia virusVVstrain LIVP 6.1.1DNAPoxviridaeMutant for J2R geneYesNoNoUniversity of veterinary medicine, germanyHuman prostate carcinoma cell lineCT1258NANAMTT assay0.1 MOI10% cell survival after 72 hoursNoNoNA No responseNANANANA26205404
OV_4098Vaccinia virusVVstrain GLV-5b451DNAPoxviridaeDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locusYesNoNoUniversity of veterinary medicine, germanyHuman prostate carcinoma cell lineCT1258NANAMTT assay0.1 MOI95% cell survival after 24 hoursNoNoNA No responseNANANANA26205404
OV_4102Vaccinia virusVVstrain GLV-5b451DNAPoxviridaeDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locusYesNoNoUniversity of veterinary medicine, germanyHuman prostate carcinoma cell lineCT1258NANAMTT assay0.1 MOI50% cell survival after 48 hoursNoNoNA No responseNANANANA26205404
OV_4106Vaccinia virusVVstrain GLV-5b451DNAPoxviridaeDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locusYesNoNoUniversity of veterinary medicine, germanyHuman prostate carcinoma cell lineCT1258NANAMTT assay0.1 MOI10% cell survival after 72 hoursNoNoNA No responseNANANANA26205404
OV_4288AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman prostate carcinoma22Rv14000 cells per wellNAMTT assay10 pfu39.1 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4308AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman prostate adenocarcinomaPC-34000 cells per wellNAMTT assay10 pfu72.7 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4321AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman prostate carcinomaDu1454000 cells per wellNAMTT assay10 pfu91.4 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4909Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay0.1 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4910Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay1 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4911Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay10 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4912Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay50 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4913Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay0.1 MOI100% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4914Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay1 MOI90% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4915Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay10 MOI30% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4916Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay50 MOI15% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4917Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay0.1 MOI70% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4918Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay1 MOI40% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4919Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay10 MOI15% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4920Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneJilin University chinaHuman prostate cancer cell linePC-3M1 million cells per wellNAMTT assay50 MOI15% cell viability after 7 daysNoNoNA No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_5068Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman prostate cancer cell lineDu1451.0E+3 cells per wellNACrystal violet staining10 MOI70% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5622Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostate cancer cell lineDu14580% confluencyNAMTT assay31 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5623Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostate cancer cell linePC-380% confluencyNAMTT assay3×10³ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5634Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostate small cell carcinomaNCI-H66080% confluencyNAMTT assay1.0 ×10⁵ pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5842Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostae carcinoma cell lineDu14580% confluencyNANA31 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5843Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman prostae carcinoma cell linePC-380% confluencyNANA3.1 ×10³ pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5854Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman small cell prostae carcinoma cell lineNCI-H66080% confluencyNANA1.0 ×10⁵ pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5888Respiratory synctial virusMutantRNAParamyxoviridaeNoneYesNoNoATCCHuman prostate cancer cell linePC-3NANAMTT assay2 MOI20% cell survived after treatmentNoNoNA No responseNAInduction of apoptosis as measured by TUNEL assayNANAUS9241998
OV_5893AdenovirusCGTG-602DNAAdenoviridaeVirus E1A promoter is replaced by human E2F1 promoterYesNoNoATCCHuman prostate cancer cell linePC-3-MM2NANAMTT assay1 ×10⁴ pfuAll cell death occurs after 100 daysNoNoNA No responseNANANANAUS9410129