| Compound | Cepharanthine |
| NPACT-Id | NPACT01166 |
| IUPAC | - |
| Synonyms | (+)-Cepharanthine;Cepharantin;O-Methylcepharanoline;Cepharanthine (JAN);6',12'-Dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))oxyacanthan;Oxyacanthan, 6',12'-dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))-; |
| PubChem Id | 10206 |
| Class | Alkaloids |
| In-vitro anticancer activity | 1 cancer cell lines |
| In-Vivo anticancer activity | No |
| Targets | AKT1 | CASP3 | CYCS | MAPK1 | MAPK3 | MAPK8 | PARP1 | All | |
| Properties | Physical Elemental Topological |
| InChi Key | YVPXVXANRNDGTA-WDYNHAJCSA-N |
| InChi | 1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,29+/m1/s1 |
| SMILES | O1c2c3[C@@H](N(CCc3cc3OCOc23)C)Cc2ccc(Oc3cc(C[C@H]4N(CCc5c4cc1c(OC)c5)C)ccc3OC)cc2 |
|
SMART | [H]C1=C([H])C2=C([H])C([H])=C1OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]1([H])[N@](C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC4=C5C(=C([H])C6=C4OC([H])([H])O6)C([H])([H])C([H])([H])[N@](C([H])([H])[H])[C@@]5([H])C2([H])[H])C([H])=C13 |
| CAS No. | 481-49-2 |
|
Structure
Download | 
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| Cross Refrence in other databases |
| Super Natural | 000481492 |
| CTD | C006947 |
| HIT | C0371 |
| NCI-60 GI50 data | - |
| Suppliers | ABI Chem, AKos Consulting & Solutions, Ambinter, ChemMol, FINETECH, Hangzhou APIChem Technology, MolPort, Vitas-M Laboratory, |
| Drug-Likeliness Filters | Lipinski's rule of five | No |
| Ghose filter | No |
| Veber filter | Yes |
| Muegge Filter | No |
| Similarity Search | Human metabolite database | FDA approved drugs |