| Compound | (R)-tylophorine |
| NPACT-Id | NPACT01053 |
| IUPAC | - |
| Synonyms | Dibenzo[f,2-b]isoquinoline, 9,11,12,13,13a,14-hexahydro-2,3,6,7-tetramethoxy-, (S)-;2,3,6,7-Tetramethoxyphenanthro(9,10:6,7')indolizidine;2,6,7-Tetramethoxyphenanthro[9,10:6',7']indolizidine |
| PubChem Id | 92114 |
| Class | Alkaloids |
| In-vitro anticancer activity | 1 cancer cell lines |
| In-Vivo anticancer activity | No |
| Targets | CCNB1 | CDK2 | CYC3B | All | |
| Properties | Physical Elemental Topological |
| InChi Key | SSEUDFYBEOIWGF-AWEZNQCLSA-N |
| InChi | 1S/C24H27NO4/c1-26-21-9-16-15-8-14-6-5-7-25(14)13-20(15)19-12-24(29-4)23(28-3)11-18(19)17(16)10-22(21)27-2/h9-12,14H,5-8,13H2,1-4H3/t14-/m0/s1 |
| SMILES | O(c1cc2c3C[C@H]4N(CCC4)Cc3c3c(c2cc1OC)cc(OC)c(OC)c3)C |
|
SMART | [H]C1=C2C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C3=C(C2=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])[N@@]1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C3([H])[H] |
| CAS No. | 482-20-2 |
|
Structure
Download | 
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| Cross Refrence in other databases |
| Super Natural | 000482202 |
| CTD | C004218 |
| HIT | C0031 |
| NCI-60 GI50 data | 482-20-2 |
| Suppliers | AAA Chemistry, ABI Chem, |
| Drug-Likeliness Filters | Lipinski's rule of five | Yes |
| Ghose filter | Yes |
| Veber filter | Yes |
| Muegge Filter | Yes |
| Similarity Search | Human metabolite database | FDA approved drugs |